全文获取类型
收费全文 | 96篇 |
免费 | 3篇 |
专业分类
化学 | 62篇 |
晶体学 | 1篇 |
力学 | 3篇 |
数学 | 2篇 |
物理学 | 31篇 |
出版年
2023年 | 4篇 |
2022年 | 12篇 |
2021年 | 7篇 |
2020年 | 4篇 |
2019年 | 3篇 |
2018年 | 5篇 |
2017年 | 4篇 |
2016年 | 11篇 |
2015年 | 2篇 |
2014年 | 1篇 |
2013年 | 8篇 |
2012年 | 3篇 |
2011年 | 3篇 |
2010年 | 6篇 |
2009年 | 4篇 |
2008年 | 3篇 |
2007年 | 2篇 |
2006年 | 1篇 |
2003年 | 2篇 |
2002年 | 2篇 |
2001年 | 2篇 |
1999年 | 1篇 |
1996年 | 2篇 |
1995年 | 2篇 |
1989年 | 1篇 |
1987年 | 1篇 |
1983年 | 2篇 |
1978年 | 1篇 |
排序方式: 共有99条查询结果,搜索用时 62 毫秒
1.
Inas A. Abdallah Sherin F. Hammad Alaa Bedair Mohamed A. Abdelaziz Neil D. Danielson Ahmed H. Elshafeey Fotouh R. Mansour 《Biomedical chromatography : BMC》2022,36(6):e5365
Favipiravir is a potential antiviral medication that has been recently licensed for Covid-19 treatment. In this work, a gadolinium-based magnetic ionic liquid was prepared and used as an extractant in dispersive liquid–liquid microextraction (DLLME) of favipiravir in human plasma. The high enriching ability of DLLME allowed the determination of favipiravir in real samples using HPLC/UV with sufficient sensitivity. The effects of several variables on extraction efficiency were investigated, including type of extractant, amount of extractant, type of disperser and disperser volume. The maximum enrichment was attained using 50 mg of the Gd-magnetic ionic liquid (MIL) and 150 μl of tetrahydrofuran. The Gd-based MIL could form a supramolecular assembly in the presence of tetrahydrofuran, which enhanced the extraction efficiency of favipiravir. The developed method was validated according to US Food and Drug Administration bioanalytical method validation guidelines. The coefficient of determination was 0.9999, for a linear concentration range of 25 to 1.0 × 105 ng/ml. The percentage recovery (accuracy) varied from 99.83 to 104.2%, with RSD values (precision) ranging from 4.07 to 11.84%. The total extraction time was about 12 min and the HPLC analysis time was 5 min. The method was simple, selective and sensitive for the determination of favipiravir in real human plasma. 相似文献
2.
The radical anion of 2,5-dicyano-1,5-hexadiene is shown to undergo Cope cyclization in a flowing afterglow-triple quadrupole apparatus. The cyclic structure of the 2,5-dicyano-1,5-hexadiene radical anion was established by using chemical reactivity. The ion reacts with CO2 and CS2 by addition, whereas the radical anions of closed-shell molecules such as fumaronitrile do not react with these reagents. The ion exhibits reactivity characteristic of a distonic ion in that it sequentially adds CO2 and NO or NO2. It reacts with NO by forming a product at m/z 135 corresponding to addition followed by loss of HCN. The reactivity and CID spectrum of the product ion at m/z 135 agrees with that of oximate ion, which requires a cyclic precursor ion. Attempts to generate radical anions of acrylonitrile and 2,6-dicyano-1,6-heptadiene were unsuccessful, providing additional evidence against a linear structure as a stable structure for 2,5-dicyano-1,5-hexadiene radical anion. The cyclization of the radical anion of the 2,5-dicyano-1,5-hexadiene is the first example of an electron-catalyzed Cope cyclization. 相似文献
3.
4.
Moamen S. Refat Gehad G. Mohamed Mohamed Y. S. Ibrahim Hamada M. A. Killa Hammad Fetooh 《Russian Journal of General Chemistry》2013,83(12):2479-2487
Solid complexes have been prepared and characterized by IR, UV-Vis, elemental analysis, and 1H NMR. Indomethacin forms complexes with Cd(II), Ce(III), and Th(IV) ions in molar ratios (ligand: metal) (2: 1), (3: 1), and (4: 1), respectively. The IR spectra of the complexes suggest that the Indomethacin behaves as a monobasic monodentate ligand coordinated to the metal ions via the deprotonated carboxylate group. Prepared complexes exhibit higher antimicrobial activity against several microorganisms, compared to free ligand. 相似文献
5.
Mohammad Nasser H. EL-Sherbiny Gamal M. Hammad Ali A. Askar Ahmed A. El- Nour Salwa A. Abou 《Cellulose (London, England)》2022,29(3):1791-1805
Cellulose - Antibacterial coatings based on bacterial cellulose (BC) have been widely used in many fields including food packaging and wound dressing. In this study, we aimed to synthesis of... 相似文献
6.
Wurood kh. Al-lehaibi Khulood A. Al-makhzomi Hani Sh. Mohammed Hamid Hammad Enezei Mohammad Khursheed Alam 《Molecules (Basel, Switzerland)》2021,26(7)
Background: The study examined the oral microbiota, physiological and immunological changes in patients using thermoplastic retainers during three months of use. Methods: The study included several steps. Firstly, 10 swabs were collected from the buccal and palatal surfaces of the teeth of the patients, approximately 2 mL of saliva was collected from the same patients and 2 mL of saliva was collected from 10 healthy people to measure the pH and secretory IgA level. This was followed by the isolation and identfication of the bacterial isolates in the patient samples. Then, isolate susceptibility toward chlorhexidine (CHX) and their adhesion ability to thermoplastic retainer surfaces was measured. In addition to that the study estimated the numbers of Lactobacillus and Streptooccus mutans colonies during three months and finally, a comparsion of pH acidity and IgA level between the patients and healthy people was performed. The results showed the predominant bacteria during the three months were Lactobacillus spp. and Streptococcus spp. followed by different rates of other bacteria. Raoultella ornithinolytica showed more resistance to CHX while Lactobacillus spp. showed more sensitivity. Streptococcus mutans colony levels were higher than Lactobacillus spp. colonies during the three months, also S. mutans had the highest value in adherence to retainer thermoplastic. Finally, pH acidity showed a highly significant difference (p ≤ 0.05) in the third month, like IgA levels (p ≤ 0.05). Conclusions: According to the results obtained from the current study, the researchers noted that the thermoplastic retainers helped change the oral cavity environment. 相似文献
7.
Hammad Ullah Alessandro Di Minno Cristina Santarcangelo Haroon Khan Jianbo Xiao Carla Renata Arciola Maria Daglia 《Molecules (Basel, Switzerland)》2021,26(8)
Helicobacter pylori (H. pylori) infections affect almost half of the world’s population, with gradually increasing incidence in developed countries. Eradication of H. pylori may provide significant benefits to the affected individual by healing a number of gastrointestinal and extra-digestive disorders. But due to increased microbial resistance and lack of patient adherence to the therapy, the eradication rate of H. pylori is below 80% with current pharmacological therapies. The usage of botanicals for their therapeutic purposes and medicinal properties have been increased in last decades. They can be use as alternative H. pylori treatments, especially against drug-resistant strains. Epidemiological studies have revealed that people with lower vegetable and micronutrient intake may be at increased risk of H. pylori infection. We have undertaken a review of clinical trials to evaluate the efficacy of vegetable extracts and micronutrients in patients with H. pylori. Various databases, such as Google Scholar, PubMed, Scopus, Web of Science, and the Cochrane Library, were searched for the articles published in English. A total of 24 clinical studies (15 for vegetable extracts and 9 for micronutrients) were selected to be reviewed and summarized in this article. Vegetable extracts (Broccoli sprouts, curcumin, Burdock complex, and Nigella sativa) and micronutrients (vitamin C and E) were not found to be as effective as single agents in H. pylori eradication, rather their efficacy synergized with conventional pharmacological therapies. Conversely, GutGard was found to be significantly effective as a single agent when compared to placebo control. 相似文献
8.
Hammad Ullah Yaseen Hussain Cristina Santarcangelo Alessandra Baldi Alessandro Di Minno Haroon Khan Jianbo Xiao Maria Daglia 《Molecules (Basel, Switzerland)》2022,27(6)
Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, salting, or fermentation. Water activity, temperature, redox potential, preservatives, and competitive microorganisms are the most important approaches used in the preservation of food products. Preservative agents are generally classified into antimicrobial, antioxidant, and anti-browning agents. On the other hand, artificial preservatives (sorbate, sulfite, or nitrite) may cause serious health hazards such as hypersensitivity, asthma, neurological damage, hyperactivity, and cancer. Thus, consumers prefer natural food preservatives to synthetic ones, as they are considered safer. Polyphenols have potential uses as biopreservatives in the food industry, because their antimicrobial and antioxidant activities can increase the storage life of food products. The antioxidant capacity of polyphenols is mainly due to the inhibition of free radical formation. Moreover, the antimicrobial activity of plants and herbs is mainly attributed to the presence of phenolic compounds. Thus, incorporation of botanical extracts rich in polyphenols in perishable foods can be considered since no pure polyphenolic compounds are authorized as food preservatives. However, individual polyphenols can be screened in this regard. In conclusion, this review highlights the use of phenolic compounds or botanical extracts rich in polyphenols as preservative agents with special reference to meat and dairy products. 相似文献
9.
The acoustic protection afforded by a balcony open to the street but enclosed on all other sides was investigated by means of one-tenth scale models. The results indicate that the protection is slight and the frequency invariant when the receiver is exposed to a direct path. The protection increases with increased sound incident angle and balcony depth and becomes frequency dependent when the direct path between source and receiver is screened.In general, the protection measured by the author, using scale models, compared well with the full-scale measurements of other workers. The measured protection of a balcony is considerably improved when perforated screens of unusual geometry are installed.A maximum protection due to these screens is obtained at first and second floor levels and at balcony depths of 2 m and less. 相似文献
10.
The energy spectra of three types of two-dimensional potentials(we will call them‘Davidson-like potentials’(DLPs)),characterized by four minima separated by barriers,are investigated.The predictions for spectra and wave functions are obtained by using the nine-point finite-difference method.For these potentials,with the existence of a single configuration,a transition of spectra,as a function of barrier height,is covered from tunneling splitting modes to fluctuations phenomena,with equal peaks wave functions,crossing to the spectra of purely anharmonic oscillator potentials(AOPs).A different type of phase transition occurs when two(or more)configurations coexist.With the change of the parameters,a transition of spectra is covered from coexistence phenomena of two distinct quantum tunneling modes to fluctuations phenomena,with unequal peaks wave functions,crossing to the spectra of purely AOPs.Using DLPs,a particular application of the coherent quadropole-octupole model to describe energy bands with alternating parity of the nuclei100Mo,146,148Nd,148,150Sm,220Ra,220,222Rn,and220,222Th is presented.The global parametrization of the model for the selected nuclei is achieved. 相似文献