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1.
A facile and convenient protocol was developed for the synthesis of diindolylmethanes in short reaction time and high yields using newly synthesized complex as an efficient recyclable heterogeneous catalyst. All synthesized compounds were characterized by IR, NMR spectra and elemental analysis. 相似文献
2.
Russian Journal of Organic Chemistry - Tannic acid‐functionalized silica‐coated Fe3O4 nanoparticles (Fe3O4@SiO2@tannic acid) were synthesized and characterized by transmission electron... 相似文献
3.
Sajedi Mohammad Mansoori Yagoub Nuri Ayat Fekri Somayeh Esquivel Dolores Navarro M Angeles 《Catalysis Surveys from Asia》2022,26(3):193-210
Catalysis Surveys from Asia - 2-(2-Pyridyl)benzimidazole (PyBzIm) was supported onto magnetic mesoporous silica, Fe3O4@SiO2@SBA-15 via the click chemistry. The supported ligand was treated with... 相似文献
4.
The paper studies nonlinear dynamics and control of a class of space station based mobile flexible two-link manipulators, normally referred to as the Mobile Servicing System (MSS).The governing nonlinear, nonautonomous and coupled equations of motion are described first followed by the modal discretizations procedure. A parametric response study suggests situations with unacceptable levels of deflections and accelerations for certain proposed missions, as well as station libration and payload positioning errors.An inverse control technique is proposed to achieve high tracking accuracy of the MSS in presence of maneuver induced disturbances. The control strategy is so designed as to regulate the libration of the Space Station as well as to insure joints tracking of prescribed trajectories, while limiting the effect of the structural vibration during large slewing maneuvres of the MSS. Two different control schemes, both based on the feedback linearization technique, are developed and their relative merit assessed.This investigation was supported by the Centers of Excellence Program, Grant No. IRIS/C-8, 5-55380, and Natural Sciences and Engineering Research Council of Canada, Grant No. A-2181. 相似文献
5.
Russian Journal of General Chemistry - Bis(indoyl)methanes have been synthesized via electrophilic reaction of indole and aldehydes in excellent yields under mild reaction conditions in the... 相似文献
6.
Microwave‐Assisted Catalyst Free Three Component Synthesis of Mono and Bis Spiro Pyrazolopyridines in Solvent Free Reaction 下载免费PDF全文
Mohammad Nikpassand Leila Zare Fekri Neda Jamshidi 《Journal of heterocyclic chemistry》2015,52(5):1580-1583
Multicomponent synthesis of mono and bis‐spiro pyrazolopyridines from isatin derivatives, indanedione, and 3‐methyl‐5‐aminopyrazole under microwave irradiation in the absence of any catalyst or solvent with high yield and short reaction time is reported. 相似文献
7.
Secretory group V phospholipase A2 (PLA2-V) is known to be involved in inflammatory processes in cellular studies, nevertheless, the biochemical and the enzymatic characteristics of this important enzyme have been unclear yet. We reported, as a first step towards understanding the biochemical properties, catalytic characteristics, antimicrobial and cytotoxic effects of this PLA2, the production of PLA2-V from dromedary. The obtained DrPLA2-V has an absolute requirement for Ca2+ and NaTDC for enzymatic activity with an optimum pH of 9 and temperature of 45 °C with phosphatidylethanolamine as a substrate. Kinetic parameters showed that Kcat/Kmapp is 2.6 ± 0.02 mM−1 s−1. The enzyme was found to display potent Gram-positive bactericidal activity (with IC50 values of about 5 µg/mL) and antifungal activity (with IC50 values of about 25 µg/mL)in vitro. However, the purified enzyme did not display a cytotoxic effect against cancer cells. 相似文献
8.
Nikpassand Mohammad Fekri Leila Zare Rahro Parissa Naddaf 《Research on Chemical Intermediates》2019,45(4):1707-1719
Research on Chemical Intermediates - A novel, efficient, one-pot, catalyst-free grinding procedure for synthesis of 6-amino-3-methyl-4-aryl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile is reported.... 相似文献
9.
Sara Nourizadeh Adeleh Divsalar Mina Fekri Behafarid Ghalandari Mahbubeh Eslami-Moghadam Ali Akbar Saboury Saba Abbasi 《Journal of fluorescence》2018,28(2):551-559
In the present study, the biological activities of a new synthesized Pt(II)-complex, 2,2′ bipyridinphenyl isopentylglycin Pt(II) nitrate was investigated via its interaction with the most important blood carrier protein of human serum albumin (HSA), using fluorescence and Far-UV circular dichroism (CD) spectroscopic techniques and also molecular docking. Moreover, cytotoxicity activity of the complex was studied against breast cancer cell line of MDA MB231 using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The Pt(II)-complex has a strong ability to quench the intrinsic fluorescence of HSA through a static quenching mechanism. According fluorescence quenching data, the binding parameters of the interaction were calculated and showed that hydrophobic interaction has an important role. The molecular docking results in coherent with fluorescence measurements illustrated that Pt(II) complex can bind to HSA at one position that located in the hydrophobic cavity of groove between drug site I and II. Also, experimental data on driving force in binding site was confirmed whereas theoretical results demonstrated Pt(II) complexinteract to HSA by hydrophobic interaction. Far-UV-CD results showed that Pt(II)-complex induced an increasing in the content of α-helical structure of the protein and stabilized it. Also, MTT assay represented growth inhibitory effect of the complex toward the breast cancer cell line. 相似文献
10.
Spectroscopic studies,structural characterization and electrochemical studies of two cobalt (III) complexes with tridentate hydrazone Schiff base ligands: Evaluation of antibacterial activities,DNA‐binding,BSA interaction and molecular docking 下载免费PDF全文
Co(III) complexes of tridentate Schiff base ligands derived from N‐(2‐hydroxybenzylideneamino)benzamide (H 2 L 1 ) and 2‐(2‐hydroxybenzylidene)hydrazine‐1‐carboxamide ( H 2 L 2 ) were synthesized and characterized using IR, Raman, 1H–NMR and UV–Vis spectroscopies. X‐ray single crystal structures of complexes 1 and 2 have also been determined, and it was indicated that these Co(III) complexes are in a distorted octahedral geometry. The cyclic voltammetry (CV) of the complexes indicates an irreversible redox behavior for both complexes 1 and 2 . The antibacterial effects of the synthesized compounds have been tested by minimum inhibitory concentration and minimum bactericidal concentration methods, which suggested that the metal complexes exhibit better antibacterial effects than the ligands against Gram‐positive bacteria. The effects of the drug (drug = ligands and complexes) on bovine serum albumin (BSA) were examined using circular dichroism (CD) spectropolarimetry, and it was revealed that the BSA (BSA, as a carrier protein) secondary structure changed in the presence of the drug. Interaction of the drug with calf‐thymus DNA (CT‐DNA) was investigated by UV–Vis absorption, fluorescence emission, CV and CD spectroscopy. Binding constants were determined using UV–Vis absorption. The results indicated that the studied Schiff bases bind to DNA, with the hyperchromic effect and non‐intercalative mode in which the metal complexes are more effective than ligands. Furthermore, molecular docking simulation was used to obtain the energetic and binding sites for the interaction of the complexes with Mycobacterium tuberculosis enoyl‐acyl carrier protein reductase (InhA), and results showed that complex 1 has more binding energy. 相似文献