Phosphorylation of Conjugated Enamines

Abstract

Introduction of benzylidene group at α-position of enamines derived from cyclic ketones substantially increases strength of C-P bond thus permitting further syntheses without splitting of the C-P bond. A wide set of phosphorylated derivatives of type (I) were prepared and their properties were studied. Combination of an enamine moiety with other nucleophilic centers such as C or N in a molecule allows to carry out cyclisation giving five- and six-membered phosphorus-containing heterocycles of types (II, III).     

Phosphorus-Containing Heterocyclic Compounds Derived from N-Vinylpyrroles

C-phosphorylation of N-vinylpyrroles with phosphorus(III) halides is shown to occur both at position 2 of the pyrrole ring and at the vinyl group. The properties of the resulting phosphorus-containing heterocyclic compounds and bis-phosphorylated N-vinylpyrroles are reported. © 1997 John Wiley & Sons, Inc. Heteroatom Chem 8: 495–499, 1997     

Muon Tomography of Large-Scale Objects

Physics of Atomic Nuclei - Cosmic ray muons arriving from the upper hemisphere to the Earth’s surface, are currently used to develop methods of muonography (analogous to radiography) of the...     

Synthesis and characterization of 4,5‐dihydro‐1H‐pyrazolo[3,4b][1,4]azaphosphinines

1,3,3‐Trimethyl‐2‐(1‐R‐3‐methyl‐5‐pyrazolyliminoethylidene)indolines were shown to undergo phosphorylation with phosphorus(III) halides at the two nucleophilic carbon centers to give fused 1,4‐azaphosphinine ring systems. Chemical properties of the synthesized compounds were characterized. For some representative compounds, detailed NMR spectroscopic investigations were performed, including the determination of ³¹P, ¹H and ³¹P, ¹³C coupling constants. © 1999 John Wiley & Sons, Inc. Heteroatom Chem 10: 391–398, 1999