Extension of a combined analytical/numerical initial value problem solver for unsteady periodic flow

Here we describe analytical and numerical modifications that extend the Differential Reduced Ejector/ mixer Analysis (DREA), a combined analytical/numerical, multiple species ejector/mixing code developed for preliminary design applications, to apply to periodic unsteady flow. An unsteady periodic flow modelling capability opens a range of pertinent simulation problems including pulse detonation engines (PDE), internal combustion engine ICE applications, mixing enhancement and more fundamental fluid dynamic unsteadiness, e.g. fan instability/vortex shedding problems. Although mapping between steady and periodic forms for a scalar equation is a classical problem in applied mathematics, we will show that extension to systems of equations and, moreover, problems with complex initial conditions are more challenging. Additionally, the inherent large gradient initial condition singularities that are characteristic of mixing flows and that have greatly influenced the DREA code formulation, place considerable limitations on the use of numerical solution methods. Fortunately, using the combined analytical–numerical form of the DREA formulation, a successful formulation is developed and described. Comparison of this method with experimental measurements for jet flows with excitation shows reasonable agreement with the simulation. Other flow fields are presented to demonstrate the capabilities of the model. As such, we demonstrate that unsteady periodic effects can be included within the simple, efficient, coarse grid DREA implementation that has been the original intent of the DREA development effort, namely, to provide a viable tool where more complex and expensive models are inappropriate. Copyright © 2002 John Wiley & Sons, Ltd.     

Study of the (p,pn) reaction in light nuclei

The (p, pn) reaction on ²H, ⁶Li, ⁷Li, ⁹Be has been studied at 47 MeV bombarding energy. Excitation energy spectra and energy sharing spectra are presented. Fragmentary information on ¹⁰B, ¹¹B and ¹²C was also obtained. Sequential decay contributions to the ⁶Li(p, pn)⁵Li¹ reaction suggest an admixture of parentage $\text{(α)π(}\text{p}{}_{\mathrm{<mtext>1</mtext><mtext>2</mtext>}}\text{)π(}\text{d}{}_{\mathrm{<mtext>5</mtext><mtext>2</mtext>}}\text{)}$ for the (3^?), 23 MeV excited state of ⁶Be. A possible 15.5 MeV excited state in ⁶Be is reported. An extensive study of the ⁹Be (p, pn)⁸Be reaction for 45 MeV protons was made. Results for θ_p = θ_n = 25°, 30°, 35°, 40°, 45°, 55°, 65°; θ_n = 40°, θ_p = 25°, 30°, 35°, 40°, 45°, 55°, 65°; θ_p/θ_n = 40°/45°, 38.5° are reported and compared to DWIA calculations. Agreement is good when the lower momentum components of the wave function are sampled, and deteriorates as higher momenta are required. Results are in agreement with the Cohen and Kurath spectroscopic factors for ⁹Be.     

Comparison of the noncoplanar 6Li(p,pd)4He reactions at 120 and 200 MeV

The ⁶Li(p, pd)⁴He reaction was studied at 200.2 MeV, at the quasi-free angle pair (θ_p, θ_d) = (54°, ?48.9°), for noncoplanarity angles φ from 0° to 28°. ⁶Li αd spectroscopic factors of 0.84 and 0.76 are deduced from our coplanar data at this energy and 120 MeV, respectively, for ground-state 2S Woods-Saxon wave functions. A recent microscopic three-body calculation predicts spectroscopic factors from 0.70 to 0.75; using the ground-state wave functions from this study, we deduce a factor of 0.76 from the 200 MeV data. DWIA calculations fit the measured integrated cross sections versus φ for spectator momenta P_α ? 100 MeV/c at both bombarding energies, but underpredict them for larger P_α. Momentum form factors were better reproduced with 1S αd cluster wave functions for a soft-core bound-state potential than with the 2S Woods-Saxon wave functions, but the former wave functions generate unphysically large (～1.25) spectroscopic factors.     

新开花粉蛋白的盐酸胍去折叠过程

本文利用荧光光谱和园二色光谱了新开花粉蛋白的盐酸胍去折叠过程。结果显示：新开花粉蛋白的盐酸胍去折叠是一个只包含天然蛋白和变性终态的二态过程,与已经报道的天花粉蛋白的盐酸胍去折叠的过程不同。     

Review of nanofluids for heat transfer applications

Research on nanofluids has progressed rapidly since its enhanced thermal conductivity was first repotted about a decade ago,though much controversy and inconsistency have been reported,and insufficient understanding of the formulation and mechanism of nanofluids further limits their applications.This work presents a critical review of research on heat transfer applications of nanofluids with the aim of identifying the limiting factors so as to push forward their further development.     

A combined analytical singularity subtraction method and compact implicit differencing scheme for aerodynamic mixing

In spite of the rapid advances in both scalar and parallel computational tools, the large number and breadth of variables involved in both design and inverse problems make the use of sophisticated fluid flow models impractical. With this restriction, it may be concluded that an important family of methods for mathematical/computational development are reduced or approximate models. In this study, a combined perturbation/numerical modeling methodology is developed. The numerical portion of the model uses a compact finite difference scheme, while analytical solutions are used to resolve singular behavior that is inherent to this flow. Solutions are presented to illustrate the efficiency of this methodology.     

CD40mAb adjuvant induces a rapid antibody response that may be beneficial in post-exposure prophylaxis

Active vaccination can be effective as a post-exposure prophylaxis, but the rapidity of the immune response induced, relative to the incubation time of the pathogen, is critical. We show here that CD40mAb conjugated to antigen induces a more rapid specific antibody response than currently used immunological adjuvants, alum and monophosphoryl lipid A™.