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本文对超声引导椎旁神经阻滞治疗带状疱疹后遗神经痛(post-herpetic neuralgia,PHN)的疗效及可行性进行了分析。研究对象为2015年12月~2017年12月于我院就诊的94例PHN患者,按就诊顺序随机均分为两组,对照组给予普瑞巴林常规治疗,观察组在此基础上联合超声引导椎旁神经阻滞治疗,连续治疗4周。本文比较了治疗前、治疗1周、2周、4周后的匹兹堡睡眠质量指数(PSQI)评分、疼痛视觉模拟(VAS)评分,并评价了治疗后的综合疗效,记录了治疗期间发生不良反应情况。结果显示,较治疗前,治疗1周、2周、4周后两组VAS评分均逐渐降低,且观察组治疗后各时间点的VAS评分显著低于对照组,差异具有统计学意义(P<0.05);较治疗前,两组治疗1周、2周、4周后PSQI评分均逐渐降低,且观察组治疗后各时间点的PSQI评分显著低于对照组,差异具有统计学意义(P<0.05);观察组治疗总有效率为89.36%,对照组为78.72%,观察组显著高于对照组,差异具有统计学意义(P<0.05);两组治疗期间各项不良反应发生率差异无统计学意义(P>0.05)。本文证实了超声引导椎旁神经阻滞治疗PHN能显著改善患者神经疼痛症状,提升睡眠质量,同时具有安全性保障。 相似文献
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常见客体分子对笼型水合物晶格常数的影响 总被引:1,自引:0,他引:1
Qingguo Meng Changling Liu Chengfeng Li Xiluo Hao Gaowei Hu Jianye Sun Nengyou Wu 《物理化学学报》2020,36(11):1910010-0
Natural gas hydrates are considered as ideal alternative energy resources for the future, and the relevant basic and applied research has become more attractive in recent years. The influence of guest molecules on the hydrate crystal lattice parameters is of great significances to the understanding of hydrate structural characteristics, hydrate formation/decomposition mechanisms, and phase stability behaviors. In this study, we test a series of artificial hydrate samples containing different guest molecules (e.g. methane, ethane, propane, iso-butane, carbon dioxide, tetrahydrofuran, methane + 2, 2-dimethylbutane, and methane + methyl cyclohexane) by a low-temperature powder X-ray diffraction (PXRD). Results show that PXRD effectively elucidates structural characteristics of the natural gas hydrate samples, including crystal lattice parameters and structure types. The relationships between guest molecule sizes and crystal lattice parameters reveal that different guest molecules have different controlling behaviors on the hydrate types and crystal lattice constants. First, a positive correlation between the lattice constants and the van der Waals diameters of homologous hydrocarbon gases was observed in the single-guest-component hydrates. Small hydrocarbon homologous gases, such as methane and ethane, tended to form sI hydrates, whereas relatively larger molecules, such as propane and iso-butane, generated sⅡ hydrates. The hydrate crystal lattice constants increased with increasing guest molecule size. The types of hydrates composed of oxygen-containing guest molecules (such as CO2 and THF) were also controlled by the van der Waals diameters. However, no positive correlation between the lattice constants and the van der Waals diameters of guest molecules in hydrocarbon hydrates was observed for CO2 hydrate and THF hydrate, probably due to the special interactions between the guest oxygen atoms and hydrate "cages". Furthermore, the influences of the macromolecules and auxiliary small molecules on the lengths of the different crystal axes of the sH hydrates showed inverse trends. Compared to the methane + 2, 2-dimethylbutane hydrate sample, the length of the a-axis direction of the methane + methyl cyclohexane hydrate sample was slightly smaller, whereas the length of the c-axis direction was slightly longer. The crystal a-axis length of the sH hydrate sample formed with nitrogen molecules was slightly longer, whereas the c-axis was shorter than that of the methane + 2, 2-dimethylbutane hydrate sample at the same temperature. 相似文献
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The enlargement of the emitting aperture is usually one of the important methods of increasing vertical- cavity surface-emitting laser (VCSEL) optical output power. However, in a VCSEL with a larger aperture, the inhomogeneity in the injected current often causes inhomogeneous or even no emission. To solve this problem and to increase VCSEL output power, as well as to improve its thermal characteristics, we develop a new type of injected VCSEL with a larger aperture and a reticular electrode, where the conventional circular injection electrode of the P side is turned into a reticular one, and the heat sink is on the N side. The tests of the new VCSEL show an improvement in homogeneity in not only the injected current but also the emission intensity. The optical output power is also considerably increased, and the device optoelectronic performance is improved. 相似文献
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Xuan Zhang Yunhua Hui Changling Fang Yuan Wang Feng Han Xiaoyi Lou Essy Kouadio Fodjo Youqiong Cai Cong Kong 《Molecules (Basel, Switzerland)》2021,26(16)
A sensitive and reliable method was developed to determine methylene blue (MB) and its metabolite residues, including azure A (AZA), azure B (AZB), and azure C (AZC) in aquatic products by HPLC–MS/MS. The samples were extracted by acetonitrile and cleaned up by alumina-neutral (ALN) cartridges. The analytes were separated on a Sunfire C18 column (150 mm × 2.1 mm, 5 µm). The method was validated according to the European criteria of Commission Decision 2002/657/CE. Good linearity between 1–500 µg/L was obtained with correlation coefficients (R2) greater than 0.99. The limit of quantification (LOQ) was 1.0 µg/kg. The average recoveries at three levels of each compound (1, 5, and 10 µg/kg) were demonstrated to be in the range of 71.8–97.5%, with relative standard deviations (RSDs) from 1.05% to 8.63%. This method was suitable for the detection of methylene blue and its metabolite residues in aquatic products. 相似文献
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导致单管型白光发光二极管快速光衰的实验研究 总被引:1,自引:1,他引:0
很多国内封装的单管(Lamp)型白光发光二极管(LED)半光衰时间往往较短,这与大功率白光LED有很大不同.为了找出导致单管型白光LED快速光衰的真正原因,在分析国内外研究现状的基础上,对不同老化时期的白光LED样品进行解剖,并对封装内部结构材质的变化进行分析.实验发现两种现象,一是有些封装体内固晶胶产生黄变,二是有些蓝光芯片上表面会形成一层深黄色薄膜.去除黄变的固晶胶,或者清洗掉芯片上表面的薄膜后重新封装,白光LED光通量均会有较大提高.荧光粉胶体和固晶胶与蓝光芯片直接接触,并对其完全包围,这两种胶体材料的变性老化对单管型白光LED的光衰有直接重要的影响. 相似文献