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Angelo Ranise Francesco LucchesiniMatteo Caviglia Silvana AlfeiAndrea Spallarossa Chiara Caneva 《Tetrahedron》2013
A simple one-pot procedure for the stereoselective synthesis of Knoevenagel-type indoles is described. The method is based on the in situ reaction of indole iminium salts (four of them are fully characterized) with acyclic symmetrical and unsymmetrical active methylene reagents in the presence of triethylamine. In general, the overall yields are moderate to good. Some of relevant reaction parameters and steric effects affecting stereoselectivity are discussed. 相似文献
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Gareth AD Hardy Nesrina Imami Mark R Nelson Ann K Sullivan Ron Moss Marlén MI Aasa-Chapman Brian Gazzard Frances M Gotch 《Journal of immune based therapies and vaccines》2007,5(1):6-12
Background
Fully functional HIV-1-specific CD8 and CD4 effector T-cell responses are vital to the containment of viral activity and disease progression. These responses are lacking in HIV-1-infected patients with progressive disease. We attempted to augment fully functional HIV-1-specific CD8 and CD4 effector T-cell responses in patients with advanced chronic HIV-1 infection. 相似文献3.
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The representations of the Riemann and the Weyl tensors of a four-dimensional Riemannian manifold through covariant derivatives of third-order potentials are examined in detail. The Weyl tensor always admits a completely general representation whereas the Riemann tensor does not. Nevertheless there exists a class of Riemannian manifolds whose Riemann tensors may be calculated in terms of potentials; in this connection, specific examples are exhibited explicitly. The possibility of introducing gauges on the potentials is reexamined in connection with the previous result. New properties of the representations are also discussed. 相似文献
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Starting from Helmholtz's equation in inhomogeneous media, the associated radial second‐order equation is investigated through a Volterra integral equation. First the integral equation is considered in a sphere. Boundedness, uniqueness and existence of the (regular) solution are established and the series form of the solution is provided. An estimate is determined for the error arising when the series is truncated. Next the analogous problem is considered for a spherical layer. Again, boundedness, uniqueness and existence of two base solutions are established and error estimates are determined. The procedure proves more effective in the sphere. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
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