排序方式: 共有17条查询结果,搜索用时 15 毫秒
1.
Nanotechnology promises to enhance the functionality and sensitivity of miniaturized analytical systems. For example, nanoscale transport systems, which are driven by molecular motors, permit the controlled movement of select cargo along predetermined paths. Such shuttle systems may enhance the detection efficiency of an analytical system or facilitate the controlled assembly of sophisticated nanostructures if transport can be coordinated through complex track networks. This study determines the feasibility of complex track networks using kinesin motor proteins to actively transport microtubule shuttles along micropatterned surfaces. In particular, we describe the performance of three basic structural motifs: (1) crossing junctions, (2) directional sorters, and (3) concentrators. We also designed track networks that successfully sort and collect microtubule shuttles, pointing the way towards lab-on-a-chip devices powered by active transport instead of pressure-driven or electroosmotic flow. 相似文献
2.
George D. Bachand Amy Allen Marlene Bachand Komandoor E. Achyuthan Jean Clare Seagrave Susan M. Brozik 《Journal of nanoparticle research》2012,14(10):1-10
This study explores the viability of rare earth-doped zirconia nanophosphors as probable candidates for white light emission. Undoped ZrO2 and single- and double-doped ZrO2:M (where M?=?Tb3+ and Eu3+) nanophosphors have been synthesized using a simple sonochemical process. The products were characterized using X-ray diffraction, scanning electron microscopy (SEM), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM), energy dispersive X-ray spectroscopy (EDS), and photoluminescence spectrophotometry. The SEM micrographs show that resultant nanoparticles have dendritic shape. TEM and HRTEM studies showed that the size of the majority of the nanoparticles were around 28?±?5?nm. Characteristic blue and green emission from Tb3+ ions and red from Eu3+ dopant ions were observed. The CIE coordinates of the double-doped ZrO2:Tb3+ (1.2?%):Eu3+ (0.8?%) nanophosphor lie in the white light region of the chromaticity diagram and show promise as good phosphor materials for new lighting devices. 相似文献
3.
The effects of coupled vibrations on the piezoelectric properties and electroacoustic transducer performance of radially polarized hollow cylindrical elements as a function of the choice of height-to-diameter ratio have been well documented [J. Acoust. Soc. Am. 120(3), 1374-1380 (2006); J. Acoust. Soc. Am. 122(6), 3419-3427 (2007)]. This letter presents experimental work on the effects of coupled (circumferential, axial, and flexural) vibrations on the resonance frequencies, effective electromechanical coupling coefficient, and acoustical performance of tangentially polarized piezoceramic cylindrical elements. Comparisons are made with analytical predictions of the properties of uniformly circumferentially polarized cylinders. 相似文献
4.
Aronov B Brown DA Bachand CL 《The Journal of the Acoustical Society of America》2007,122(6):3419-3427
An experimental investigation of the effects of coupled vibrations on the acoustical performance of underwater transducers made from radially polarized, thin walled, air-backed, piezoelectric cylinders as a function of their height-to-diameter aspect ratio is presented. Characteristics of the frequency response, directivity patterns, and effectiveness of the transducers are considered in comparison with analogous characteristics for the transducers comprised of mechanically separated rings, otherwise having the same geometry. Recommendations are made on the application of cylindrical piezoelectric elements with different aspect ratios for underwater transducer applications. 相似文献
5.
Laser Machined Plastic Laminates: Towards Portable Diagnostic Devices for Use in Low Resource Environments 下载免费PDF全文
Jason C. Harper Bryan D. Carson George D. Bachand William D. Arndt Melissa R. Finley C. Jeffrey Brinker Thayne L. Edwards 《Electroanalysis》2015,27(11):2503-2512
Despite significant progress in development of bioanalytical devices cost, complexity, access to reagents and lack of infrastructure have prevented use of these technologies in resource‐limited regions. To provide a sustainable tool in the global effort to combat infectious diseases the diagnostic device must be low cost, simple to operate and read, robust, and have sensitivity and specificity comparable to laboratory analysis. In this mini‐review we describe recent work using laser machined plastic laminates to produce diagnostic devices that are capable of a wide variety of bioanalytical measurements and show great promise towards future use in low‐resource environments. 相似文献
6.
H. Hess J. Clemmens C.M. Matzke G.D. Bachand B.C. Bunker V. Vogel 《Applied Physics A: Materials Science & Processing》2002,75(2):309-313
Molecular shuttles based on microtubules propelled by motor proteins can be guided on surfaces by adsorbing motors in chemical
patterns or by using open guiding channels. While chemical patterns can guide microtubules based on a Brownian ratchet mechanism,
the rigidity of the microtubules limits guiding to features with dimensions on the order of their persistence length (5 mm).
To achieve guiding on micron-scale dimensions, physical barriers are required which can exploit the forces exerted by multiple
motors to bend tubules into tight radii of curvature. Microtubule guiding is illustrated for the case of a special ratchet
pattern that is capable of sorting microtubules on the basis of the direction of their motion.
Received: 3 December 2001 / Accepted: 11 February 2002 / Published online: 22 April 2002 相似文献
7.
Cumulant functions are introduced to describe the statistical state of a radiation field. These functions are simply related
to the optical coherence functions but have some interesting features. It is shown that if the cumulant functions of all orders
greater than some numberN
0 vanish then they also vanish for all orders greater than 2. Thermal field is the only field having this property. This property
holds whether the field is described by a classical stochastic process or by a quantum density operator. Further the particular
operator ordering used in defining these cumulant functions for the quantized field affects only the second order cumulant
function. To describe the statistical state of a vector field such as partially polarized or unpolarized radiation, one would
need to introduce cumulant tensors. 相似文献
8.
Spoerke ED Bachand GD Liu J Sasaki D Bunker BC 《Langmuir : the ACS journal of surfaces and colloids》2008,24(14):7039-7043
Microtubules (MTs) are polar protein filaments that participate in critical biological functions ranging from motor protein direction to coordination of chromosome separation during cell division. The effective facilitation of these processes, however, requires careful regulation of the polar orientation and spatial organization of the assembled MTs. We describe here an artificial approach to polar MT assembly that enables us to create three-dimensional polar-oriented synthetic microtubule organizing centers (POSMOCs). Utilizing engineered MT polymerization in concert with functionalized micro- and nanoscale particles, we demonstrate the controllable polar assembly of MTs into asters and the variations in aster structure determined by the interactions between the MTs and the functionalized organizing particles. Inspired by the aster-like form of biological structures such as centrosomes, these POSMOCs represent a key step toward replicating biology's complex materials assembly machinery. 相似文献
9.
MA Freitas CL Hendrickson AG Marshall 《Rapid communications in mass spectrometry : RCM》1999,13(15):1639-1642
We present a novel approach for the determination of activation energy for the unimolecular dissociation of a large (>50 atoms) ion, based on measurement of the unimolecular dissociation rate constant as a function of continuous-wave CO(2) laser intensity. Following a short ( approximately 1 s) induction period, CO(2) laser irradiation produces an essentially blackbody internal energy distribution, whose 'temperature' varies inversely with laser intensity. The only currently available method for measuring such activation energies is blackbody infrared radiative dissociation (BIRD). Compared with BIRD, FRAGMENT: (a) eliminates the need to heat the surrounding ion trap and vacuum chamber to each of several temperatures (each requiring hours for temperature equilibration); (b) offers a three-fold wider range of effective blackbody temperature; and (c) extends the range of applications to include initially cold ions (e.g., gas-phase H/D exchange). Our FRAGMENT-determined activation energy for dissociation of protonated bradykinin, 1.2 +/- 0.1 eV, agrees within experimental error to the value, 1.3 +/- 0.1 eV, previously reported by Williams et al. from BIRD experiments. Copyright 1999 John Wiley & Sons, Ltd. 相似文献
10.
The electromechanical properties of thin tangentially polarized, stripe-electroded piezoceramic elements are considered. Theoretical analysis is made based on a piecewise linear approximation of the actual nonuniform electric field in the volume of the stripe-electroded cylinder design. Analytical expressions are derived for the electromechanical properties (including the effective coupling coefficient) of the tangentially polarized elements as a function of the geometry and electrode configuration (i.e., electrode width and spacing). The properties of stripe-electroded cylinders are calculated and compared with the ideal case of a uniform circumferential electric field, which may be realized in practice with segmented cylinders comprised of 33-polarized bar elements. The reasons for the reduction in the effective coupling coefficient of tangentially polarized stripe-electroded cylinders compared to the ideal coupling coefficient k(33) achievable with the segmented cylinder designs are discussed. The results of calculations of the electromechanical properties are in good agreement with experimentally obtained data on a variety of samples. 相似文献