ESI outcompetes other ion sources in LC/MS trace analysis

Choosing an appropriate ion source is a crucial step in liquid chromatography mass spectrometry (LC/MS) method development. In this paper, we compare four ion sources for LC/MS analysis of 40 pesticides in tomato and garlic matrices. We compare electrospray ionisation (ESI) source, thermally focused/heated electrospray (HESI), atmospheric pressure photoionisation (APPI) source with and without dopant, and multimode source in ESI mode, atmospheric pressure chemical ionisation (APCI) mode, and combined mode using both ESI and APCI, i.e. altogether seven different ionisation modes. The lowest limits of detection (LoDs) were obtained by ESI and HESI. Widest linear ranges were observed with the conventional ESI source without heated nebuliser gas. In comparison to HESI, ESI source was significantly less affected by matrix effect. APPI ranked second (after ESI) by not being influenced by matrix effect; therefore, it would be a good alternative to ESI if low LoDs are not required.

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Characteristics and safety of nano-sized cellulose fibrils

A finely ground fibrillated cellulose was fractionated into separate size fractions. The characteristics of the smallest size fractions were studied, and the toxicity to humans was tested as part of a safety assessment. Morphological studies performed with state-of-the-art methods, such as scanning electron microscopy and atomic force microscopy, showed that the fraction obtained consisted of long thin fibrils but also larger fibril agglomerates, and spherical particles were present. The finest fraction did not show any sub-lethal effects as assessed by RNA inhibition test in vitro, nor were there any indications of genotoxicity as tested by the Ames test in vitro. Systemic effects tested in vivo with the nematode were also absent. No cytotoxic effects were seen in the highest tolerated dose test in vitro, but some indication of cytotoxicity was observed in the total protein content test in vitro at the highest sample concentration. The significance of this toxicity test result should be addressed in relation to the other toxicity tests, in which no toxicity was observed, with special emphasis on the in vivo test. Given this, the overall toxicity analyses support the conclusion that nano-scale cellulose fibrils can be considered to be safe towards humans. However, the reason for the positive cytotoxicity test result and, in addition, the effect of the biocide used in sample preservation on the toxicity tests need to be clarified before generalizing these results and declaring nanocellulose to be unambiguously safe.     

The effect of a suppressor to environmental noise – A case study

The purpose of the study is to describe the effect of a suppressor to environmental noise with a typical Finnish rifle shooting range that has a shooting shelter and some noise berms. The noise measurements were carried out at Kyronpelto shooting range situated near Mikkeli in Finland. The range is equipped with wooden shooting shelter, the shooting distance is 150 m, and it has berms on sides and at the impact end. The terrain is relatively flat in the area. The best noise area reduction caused by a suppressor could be seen at angles of 315–45° from the shooting direction. The projectile noise dominates at angles 45–70°, and the effect of the suppressor is very small. To the side and back the shooting shelter has already gained significant noise attenuation, and therefore the suppressor cannot reduce the noise area much more. When there was a relatively tight shooting shelter to the side and back, the suppressor did not reduce the environmental noise area significantly any more. It can be calculated that the noise area of 65 dB (L_AImax) is reduced from 95 ha to 50 ha (0.95 km²–0.50 km²) with the help of a suppressor. However, most of the area is situated to the shooting sector and it has to be unoccupied for safety reasons.     

Effect of Armoring Composition on the Yield of Nanodiamonds and Content of Impurities

Efficiency of using detonation nanodiamonds is strongly affected by the amount and elemental composition of impurities. The study considers the possibility of affecting the yield of detonation nanodiamonds and diamond-containing stock and the content and composition of incombustible impurities in the stock and diamonds by varying the composition of the water armor (shell) of the classical TNT–hexogen (50/50) charge. As compounds affecting the above parameters were used hydrazine, urotropin, ammonia, urea, Trilon B (disodium salt of ethylene diamine tetraacetic acid), aminotetrazole, and boric acid. It was found that using urotropin was the optimal as regards a whole set of parameters. In this case, the maximum yield of detonation nanodiamonds (6.9%) and diamond-containing stock (13.4%) was obtained. A close yield of the diamond-containing stock and detonation nanodiamonds was provided by using hydrazine and urea in the armor. Use of boric acid in the armor can substantially diminish the variety of impurity elements in the diamond-containing stock and detonation nanodiamonds at an acceptable yield of the diamond-containing stock (11.1%) and detonation nanodiamonds (6.13%). Use of pure water as the armor is inefficient.     

Improved slow-positron yield using a single crystal tungsten moderator

A well-annealed W(110) single crystal was used as a fast-to-slow positron moderator. The measured moderator efficiency at room temperature using a⁵⁸Co positron source in the backscattering geometry is =(3.2±0.4)×10^–3, roughly a factor of three better than for the best previously reported Cu(111)+S moderator. We find a stable positron moderation efficiency over a period of several weeks when maintained at pressures around 10^–9 Torr and an energy spreadE = 0.7 eV of the emitted slow positrons. An initial attempt was made to fabricate a hybrid Cu on W(110) moderator, which yielded of about 1.2×10^–3 after annealing.     

Analysis of positron diffusion data

In this paper we present and discuss experimental methods to determine the positron diffusion coefficient from slow positron beam measurements. We also evaluate the use of the annihilation line Doppler-broadening technique in positron diffusion measurements, as compared on the more commonly used method of positronium fraction. The effects of incomplete positron thermalization and uncertainties of the positron implantation profile at low-positron incident energies to the measured data are discussed. We apply the presented methods to the model case of A1(110) system in the temperature range from 20 to 500 K. This data shows that Doppler-broadening and positronium fraction measurements give consistent results for the positron diffusion coefficient in A1(110), where D₊(300 K) = 1.7(2) cm²/s with the temperature dependence D₊ T ^–0.62(3).     

Thin films for slow positron generation

We report on calculated slow-positron yields from m thick W(110) and Cu(111) single crystals in a transmission geometry to be used in conjuction with a²²Na ⁺ source. The fast to slow positron moderation efficiencies were found to be comparable ( 10^–3 to the more conventional single-crystal moderators used in the backscattering geometry with a⁵⁸Co source. This allows the construction of more simplified slow-positron beams. We also calculate the brightness enhancement and efficiency of ultrathin single-crystal metal foils used for remoderation of the slow-positron beam. The results are consistent with recent experiments, while they are smaller than previous theoretical estimates.     

Non-Gaussianity from preheating

We consider a two-field model for inflation where the second order metric perturbations can be amplified by a parametric resonance during preheating. We demonstrate that there can arise a considerable enhancement of non-Gaussianity sourced by the local terms generated through the coupled perturbations. We argue that the non-Gaussianity parameter could be as large as f(NL) approximately 50. Our results may provide a useful test of preheating in future cosmic microwave background experiments.     

Correlated vacancy migration below 200 k in neutron-irradiated iron

The increase of positron parameters in neutron-irradiated α-iron around 180 K is shown to be due to correlated vacancy migration within displacement cascades. Therefore the recent attempt to use positron annihilation in neutron-irradiated iron as an evidence for interstitial migration at stage III is internally inconsistent and incompatible with well-established experimental results.     

High velocity dry spinning of nanofibrillated cellulose (CNF) filaments on an adhesion controlled surface with low friction

A new process for preparing thin cellulose nanofibril (CNF) filaments (thickness of 16 µm) was investigated by utilizing the dry spinning approach. In the process, CNF hydrogel was extruded through a fine nozzle onto an adhesion controlled capstan (drum) with low friction (slippery surface) at a speed of up to 11 m/s. The utilized capstan enables excellent line speed control when the slippery surface is applied, and prevents drying shrinkage of the spun filaments. The mechanical properties of prepared filaments can be optimized with the stretch ratio, the ratio of the speed of the drum surface, and the CNF jet flow. The developed method allows for manufacturing thin CNF filaments with an elevated spinning rate in a more controlled manner.