BIOLOGICAL EFFECT OF THE RABBIT LIVER IRRADIATED WITH FOCOUSED ULTRASOUND IN VIVO——HISTOCHEMICAL CHANGES

Rabbits'livers were irradiated by focused ultrasond with intensity of 30 W/cm~2,at the frequency of 1.06MHz,for 3 mins directly.The treated animals were sacrificed in 1 day,3 days,7 days,1 month and 2 monthsafer irradiation.Then the irradiated area of the liver was cut off and studied with routine histological H.E.method and some histochemical techniques,including the demonstration of adnosine triphospbatase(ATPase),thiamin pyrophosphatase(TPPase),nonspecific esterase(NSEase),succinate dehydrogenase(SDHase)and glycogen.The histological and histochemical changes in this experiment are as follows:(1)TheCavitational vesicles produced in the cytoplasm of light lesion hepatic cell squeeze the nucleus to the margin ofthe cell and extend the contour of hepatic cell to a ball-shape.All the ball-shape cells in the hepatic corddecrease their contact surface and are apt to be separated from one another.(2)The activities of ATPase,TTPase,NSEase and SDHase in the heavy lesion cells decrease vigorously,or even no acti