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为揭示胶束水溶液突扩流的减阻特性,实验研究了质量分数为1×10~(-4),2×10~(-4)的十六烷基三甲基溴化铵水溶液通过管径比为1:1.52的突扩的流动阻力行为.实验结果表明,在直管段最大减阻率都可达到70%的两给定质量分数的胶束水溶液,其突扩局部阻力系数,在较低雷诺数区域,较牛顿流体仅有10%~20%程度的降低,呈现局部低减阻特性;在较高雷诺数区域远大于牛顿流体,尤其当突扩进口流快失去减阻能力时,甚至接近牛顿流体的1.5倍,呈现明显的局部增阻行为.胶束水溶液减阻流,在突扩下游再次形成充分发展流所需的下游长度,远大于牛顿流体的7.8倍下游管径(45倍突扩台阶高度),流入突扩前完全失去减阻能力的质量分数为2×10~(-4)的胶束水溶液流,所需的突扩下游长度达到最大,约合158倍下游管径(920倍突扩台阶高度).通过胶束水溶液流变特性的实验分析认为,减阻水溶液突扩流的阻力行为与它的胶束网联结构的形成及松弛的时间特性密切相关. 相似文献
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研究和开发了基于自适应遗传算法的质子调强放疗扫描路径优化方法,并在此基础上对质子调强放疗扫描时间进行初步临床评估。利用自适应遗传算法具有的较强容错性和全空间最优搜索能力开发点扫描质子调强路径优化模块,并将其集成到自主研发的放疗计划系统,选取AAPM TG-119头颈部肿瘤和前列腺肿瘤模拟例题及两例临床病例进行测试,对比扫描路径优化前后质子放疗计划扫描路径长度。对于AAPMTG-119头颈部肿瘤和前列腺肿瘤模拟例题,总扫描路径长度分别降低了27.17%和18.72%,临床头颈部肿瘤和前列腺肿瘤病例总扫描路径长度分别降低了25.36%和32.95%,优化前后路径长度降低比率与零权重扫描点及肿瘤解剖结构有关。基于自适应遗传算法的扫描路径优化方法可减少质子调强放疗计划扫描时间,从而缩短病人治疗时间,可广泛应用于质子重扫描临床技术。The objective of this research is to study and develop a proton spot scanning path optimization method using an improved genetic algorithm for proton therapy and to evaluate the scanning time under clinical conditions. An Improved Adaptive Genetic Algorithm (IAGA) based scanning path optimization module was developed and integrated into the home-grown treatment planning system. Four cases, including two AAPM TG-119 standard cases and two clinical cases, were selected to compare their scanning path length before and after scanning path optimization. For the two AAPM TG-119 cases, the optimized scanning path length dropped by 27.17% and 18.72%, and for the corresponding clinical cases, the optimized scanning path length dropped by 25.36% and 32.95% respectively. The performance of scanning path optimization was affected by the number of zero-weight spots and connected regions in the scanning map. IAGA based scanning path optimization can reduce the total scanning path length in intensity modulated proton therapy and, therefore, can be used in spot rescanning to accommodate organ motion. 相似文献
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为揭示胶束水溶液突扩流的减阻特性,实验研究了质量分数为1×10-4, 2 ×10-4的十六烷基三甲基溴化铵水溶液通过管径比为1:1.52的突扩的流动阻力行为. 实验结果表明,在直管段最大减阻率都可达到70%的两给定质量分数的胶束水溶液,其突扩局部阻力系数,在较低雷诺数区域,较牛顿流体仅有10%~20%程度的降低,呈现局部低减阻特性;在较高雷诺数区域远大于牛顿流体,尤其当突扩进口流快失去减阻能力时,甚至接近牛顿流体的1.5倍,呈现明显的局部增阻行为. 胶束水溶液减阻流,在突扩下游再次形成充分发展流所需的下游长度,远大于牛顿流体的7.8倍下游管径(45倍突扩台阶高度),流入突扩前完全失去减阻能力的质量分数为2×10-4的胶束水溶液流,所需的突扩下游长度达到最大,约合158倍下游管径(920倍突扩台阶高度). 通过胶束水溶液流变特性的实验分析认为,减阻水溶液突扩流的阻力行为与它的胶束网联结构的形成及松弛的时间特性密切相关. 相似文献
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基于混合Batho修正的RBM剂量计算方法在仿真头模实验中的剂量学验证 总被引:3,自引:0,他引:3
基于混合Batho修正的规则束模型剂量计算方法可以根据放射治疗过程中加速器相关物理参数和从病人的医学影像数据中获取的人体组织非均匀信息计算出人体内的剂量场数据。在简要介绍该方法的基础上,通过将其计算结果与仿真头模的实测结果进行对比,初步证明了该方法可以作为一种较为可靠的快速剂量计算方法供临床治疗计划系统使用。The dose distribution can be calculated by the Regular Beam Model (RBM) dose engine based on the accelerator parameters and the inhomogeneity data of the patient for the radiotherapy planning. In this paper, the newly-developed mixed Batho correction based RBM is introduced, and then the calculation results are compared with the measured ones using the head phantom. The results demonstrate that the RBM dose engine can be used as a kind of reliable fast dose calculation tool in the clinical treatment planning system. 相似文献
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