Restoration of pseudo-spin symmetry in N = 32 and N = 34 isotones described by relativistic Hartree-Fock theory

The restoration of pseudo-spin symmetry(PSS) along the N = 32 and N = 34 isotonic chains and the physics behind are studied by applying the relativistic Hartree-Fock theory with the effective Lagrangian PKA1. Taking the proton pseudo-spin partners(π2s_(1/2), π1d_(3/2)) as candidates, the systematic restoration of PSS along both isotonic chains is found from sulphur(S) to nickel(Ni), while an obvious PSS violation from silicon(Si) to sulphur is discovered near the drip lines. The effects of the tensor force components are investigated, introduced naturally by the Fock terms, which can only partially interpret the systematics from calcium to nickel, whereas they fail for the overall trends. Further analysis following the Schr?dinger-like equation of the lower component of Dirac spinor shows that contributions from the Hartree terms dominate the overall systematics of the PSS restoration. Such effects can be self-consistently interpreted by the evolution of the proton central density profiles along both isotonic chains. In particular, the PSS violation is found to tightly relate to the dramatic changes from the bubble-like density profiles in silicon to the central-bumped ones in sulphur.     

温敏性乙二醇壳聚糖水凝胶的制备及药物缓释性能

以乙二醇壳聚糖为原料, 乙酸酐为酰化剂, 通过N-乙酰化反应, 制得了新型温敏性高分子乙酰化乙二醇壳聚糖. 通过核磁共振氢谱(¹H NMR)、 傅里叶变换红外光谱(FTIR)及试管倒置法对乙酰化乙二醇壳聚糖的结构及温敏性进行了表征, 通过扫描电子显微镜(SEM)和紫外-可见分光光度计(UV-Vis)对水凝胶的微观形貌和体外药物释放性能进行了研究. 结果表明, 随着反应时间和乙酸酐与乙二醇壳聚糖氨基摩尔比的增加, 产物的乙酰度逐渐增加; 乙酰化乙二醇壳聚糖溶液具有热可逆温敏性溶胶-凝胶转变行为, 可以通过控制乙酰化乙二醇壳聚糖的乙酰度和溶液浓度, 使溶胶-凝胶转变温度处于室温至体温(25~37 ℃)之间; 乙酰化乙二醇壳聚糖水凝胶具有“高度孔隙化且孔隙之间相互连通”的结构特点, 通过控制乙酰度和溶液浓度, 可使其孔径大小处于1~40 μm范围内; 乙酰化乙二醇壳聚糖水凝胶的乙酰度为89.90%时, 质量分数为5%~7%的水凝胶对抗癌药物吉西他滨具有缓释作用, 载药凝胶的释药时间可达3~5 d. 乙酰化乙二醇壳聚糖有望在药物释放及组织工程等领域得到广泛应用.