排序方式: 共有13条查询结果,搜索用时 15 毫秒
1.
2.
Dr. Michael Andresini Dr. Arianna Tota Prof. Leonardo Degennaro Dr. James A. Bull Prof. Renzo Luisi 《Chemistry (Weinheim an der Bergstrasse, Germany)》2021,27(69):17293-17321
Recent years have seen a marked increase in the occurrence of sulfoximines in the chemical sciences, often presented as valuable motifs for medicinal chemistry. This has been prompted by both pioneering works taking sulfoximine containing compounds into clinical trials and the concurrent development of powerful synthetic methods. This review covers recent developments in the synthesis of sulfoximines concentrating on developments since 2015. This includes extensive developments in both S−N and S−C bond formations. Flow chemistry processes for sulfoximine synthesis are also covered. Finally, subsequent transformations of sulfoximines, particularly in N-functionalization are reviewed, including N−S, N−P, N−C bond forming processes and cyclization reactions. 相似文献
3.
Catalytic chain transfer polymerization of isobutylene: The role of nucleophilic impurities 下载免费PDF全文
Tota Rajasekhar Ujjal Haldar Jack Emert Philip Dimitrov Rich Severt Rudolf Faust 《Journal of polymer science. Part A, Polymer chemistry》2017,55(22):3697-3704
Fast polymerization of isobutylene (IB) initiated by tert‐butyl chloride using ethylaluminum dichloride·bis(2‐chloroethyl) ether complex (T. Rajasekhar, J. Emert, R. Faust, Polym. Chem. 2017, 8, 2852) was drastically slowed down in the presence of impurities, such as propionic acid, acetone, methanol, and acetonitrile. The effect of impurities on the polymerization rate was neutralized by using two different approaches. First, addition of a small amount of iron trichloride (FeCl3) scavenged the impurity and formed an insoluble · impurity complex in hexanes. The polymerization rate and exo‐olefin content were virtually identical to that obtained in the absence of impurities. Heterogeneous phase scavenger (FeCl3) exhibited better performance than homogenous phase scavengers. In the second approach, conducting the polymerization in wet hexanes, the fast polymerization of IB was retained in the presence of impurities with a slight decrease in exo‐olefin content. 1H NMR studies suggest that nucleophilic impurities are protonated in the presence of water, and thereby neutralized. Mechanistic studies suggest that the rate constant of activation (ka), rate constant of propagation (kp), and rate constant of β‐proton elimination (ktr) are not affected by the presence of impurities. To account for the retardation of polymerization in the presence of impurities, delay of proton transfer to monomer in the chain transfer step is proposed. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017 , 55, 3697–3704 相似文献
4.
5.
Raimundo Bastos Nil Mansuroğlu Antonio Tortora Maria Tota 《Archiv der Mathematik》2018,110(4):311-318
We prove that a residually finite group G satisfying an identity \(w\equiv 1\) and generated by a commutator closed set X of bounded left Engel elements is locally nilpotent. We also extend such a result to locally graded groups, provided that X is a normal set. As an immediate consequence, we obtain that a locally graded group satisfying an identity, all of whose elements are bounded left Engel, is locally nilpotent. 相似文献
6.
Edward L. Briggs Arianna Tota Marco Colella Leonardo Degennaro Renzo Luisi James A. Bull 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2019,131(40):14441-14448
Sulfonimidamides are intriguing new motifs for medicinal and agrochemistry, and provide attractive bioisosteres for sulfonamides. However, there remain few operationally simple methods for their preparation. Here, the synthesis of NH‐sulfonimidamides is achieved directly from sulfenamides, themselves readily formed in one step from amines and disulfides. A highly chemoselective and one‐pot NH and O transfer is developed, mediated by PhIO in iPrOH, using ammonium carbamate as the NH source, and in the presence of 1 equivalent of acetic acid. A wide range of functional groups are tolerated under the developed reaction conditions, which also enables the functionalization of the antidepressants desipramine and fluoxetine and the preparation of an aza analogue of the drug probenecid. The reaction is shown to proceed via different and concurrent mechanistic pathways, including the formation of novel S≡N sulfanenitrile species as intermediates. Several alkoxy‐amino‐λ6‐sulfanenitriles are prepared with different alcohols, and shown to be alkylating agents to a range of nucleophiles. 相似文献
7.
We show that the structure of a dense, free-surface boundary layer granular flow is similar to the structure of a laminar liquid flow: There is a strong component of order (stratification parallel to the mean flow) superposed with a mild component of disorder (self-diffusion perpendicular to the mean flow). We also show that the self-diffusion coefficient scales with the mean velocity and propose a model that relates this scaling to the ordered structure of the flow. Last, we show that the structure of the flow imprints an oscillatory signature (similar to that found in confined granular flow) on the mean velocity profile. 相似文献
8.
9.
Michael R. Tota Jeanna M. Allen Jan O. Karolin Chris D. Geddes William W. Ward 《Photochemistry and photobiology》2016,92(5):667-677
We have cloned a novel fluorescent protein from the jellyfish Rhacostoma atlantica. The closest known related fluorescent protein is the Phialidium yellow fluorescent protein, with only a 55% amino acid sequence identity. A somewhat unusual alanine–tyrosine–glycine amino acid sequence forms the presumed chromophore of the novel protein. The protein has an absorption peak at 466 nm and a fluorescence emission peak at 498 nm. The fluorescence quantum yield was measured to be 0.77 and the extinction coefficient is 58 200 M?1 cm?1. Several mutations were identified that shift the absorption peak to about 494 nm and the emission peak to between 512 and 514 nm. 相似文献
10.
Delizia Costantino Shumyatsky Pavel Tortora Antonio Tota Maria 《Archiv der Mathematik》2019,112(1):27-32
Archiv der Mathematik - We prove that a commutator of two non-commutator words is a concise word. 相似文献