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1.
A. V. Kurkin V. V. Nesterov A. V. Karchava M. A. Yurovskaya 《Chemistry of Heterocyclic Compounds》2003,39(11):1466-1477
A new approach has been proposed to the synthesis of indole derivatives containing a chiral substituent at the nitrogen atom, comprizing Fischer indolization of phenylhydrazines with a chiral substituent at the -nitrogen atom. The initial hydrazines were obtained by the alkylation (Mitsunobu reaction applying optically active esters of lactic acid) of anilines containing an electron-accepting substituent at the amino group. Subsequent removal of the activating acceptor grouping was realized by nitrosation of the chiral secondary aniline followed by reduction of the corresponding N-nitroso compound. 相似文献
2.
N. E. Golantsov A. V. Karchava M. A. Yurovskaya 《Chemistry of Heterocyclic Compounds》2006,42(8):1021-1024
Methods of obtaining ketones and enamino esters have been developed on the basis of reactions of 1-(1-phenylethyl)indole-2-carbonitrile
with organomagnesium and organozinc compounds. Removal of a benzyl group from the indole nitrogen atom by the Grignard reagent
has been discovered.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1179–1183, August, 2006. 相似文献
3.
Dmitry I. Bugaenko Alexey A. Volkov Dr. Mikhail V. Livantsov Prof. Dr. Marina A. Yurovskaya Dr. Alexander V. Karchava 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(54):12502-12506
The visible-light-induced arylation of tertiary phosphines with aryl(mesityl)iodonium triflates to produce the quaternary phosphonium salts occurs under mild, metal, and catalyst-free conditions. Photo-excited EDA complexes between diaryliodonium salts and phosphines supposedly enable this transformation, which is difficult to achieve through the traditional ground-state reactions. Demonstrating high functional group tolerance, broad scope, and complete selectivity of the aryl group transfer, the method is particularly compatible with sterically congested phosphines, which are challenging under metal-based catalytic methods. 相似文献
4.
M. A. Yurovskaya A. V. Karchava Yu. G. Bundel' 《Chemistry of Heterocyclic Compounds》1992,28(9):1000-1003
A study has been made of the influence of solvents on the process of indolization of the methiodide of sym-3-nitrocollidine by the action of the N-methylimine of methyl ethyl ketone. An inversely proportional relationship has been found between the content of the 3,7-unsubstituted indole in the indole fractions and the donor strength of the solvent.For Communication 9, See [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, 1187–1190, September 1992. 相似文献
5.
A. V. Kurkin N. E. Golantsov A. V. Karchava M. A. Yurovskaya 《Chemistry of Heterocyclic Compounds》2003,39(1):74-82
We have developed a method for synthesis of N-substituted derivatives of indole from N-phenylalanine, including Fischer cyclization of the corresponding arylalkylhydrazones. The starting hydrazines were obtained by reduction of the corresponding nitrosamines. We have established that the optimum reduction method is to use metallic zinc in a methanol-hydrochloric acid system at low temperatures. 相似文献
6.
On the Absolute Convergence of Fourier Series 总被引:1,自引:0,他引:1
The necessary and sufficient conditions of the absolute convergence of a trigonometric Fourier series are established for continuous 2-periodic functions which in [0, 2] have a finite number of intervals of convexity, and whose nth Fourier coefficients are O((l/n; f)/n), where ( f) is the continuity modulus of the function f. 相似文献
7.
V. A. Chertkov S. V. Zubkov A. A. Ovcharenko A. V. Karchava M. A. Yurovskaya 《Chemistry of Heterocyclic Compounds》1999,35(11):1308-1312
On the basis of the overall signal line shape in the1H NMR spectra of [6,6]-closed and [5,6]-open fullerene-C60 cycloadducts with 1-(4-nitrophenyl)-3-phenylnitrile ylide we determined the values of the long range spin-spin coupling for the aliphatic proton of the heterocyclic fragment with the aromatic protons.M. V. Lomonosov State University, Moscow 119899, Russia. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1500–1505, November, 1999. 相似文献
8.
I. V. Trushkov A. V. Karchava M. A. Yarovskaya 《Chemistry of Heterocyclic Compounds》1996,32(9):1027-1034
The reduction of 2-alkylindoles containing a chiral substituent at the nitrogen atom by sodium cyanoborohydride in an acidic medium at -80°C is accompanied by the formation of indolines with S-configuration of the new chiral site at C(2). An AMI quantum chemical calculation showed that the major diastereomer has greater thermodynamic stability. However, the high diastereoselectivity of this reduction may be attributed only to the relative stability of the different conformations of the intermediate indoleninium cations leading to different diastereomers.M. V. Lomonosov Moscow State University, 119899 Moscow Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1199–1208, September, 1996. Original article submitted August 30, 1996. 相似文献
9.
A. V. Karchava I. S. Shuleva A. A. Ovcharenko M. A. Yurovskaya 《Chemistry of Heterocyclic Compounds》2010,46(3):291-301
The N-alkylation of 2- and 3-phenylsulfonylindoles under various conditions and the subsequent removal of the activating phenylsulfonyl
group by reductive desulfonylation using Raney nickel leads to N-alkylindoles in high yield. 2-Phenylsulfonylindole readily
undergoes the Mitsunobu reaction, while isomeric 3-phenylsulfonylindole is relatively inert under these conditions. 相似文献
10.