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排序方式: 共有242条查询结果,搜索用时 343 毫秒
1.
2.
L Dalla Libera M Fasolo P Cavallini E Ratti G Gaviraghi 《Journal of chromatography. A》1991,566(2):427-434
Avian myosin light-chain kinase from smooth muscle of the gizzard and its catalytic domain, derived from the intact enzyme by trypsin digestion, was purified within 30-40 min by both analytical and preparative anion-exchange high-performance liquid chromatography. The proteins obtained were more than 95% pure and retained their biological activity. The high-performance anion-exchange chromatography protocols represent a significant decrease in purification time when compared with conventional ion-exchange chromatography. 相似文献
3.
Zusammenfassung Es wurde die Möglichkeit untersucht, die Probemenge bei der Schwefelmikrobestimmung nachSchöniger, ohne das gewöhnliche Verfahren wesentlich zu modifizieren, durch Anwendung eines geänderten Kolbens zu vermindern.Innerhalb der üblichen Toleranzgrenzen liegende Ergebnisse (Standardabweichung ± 0,13%) wurden mit Einwaagen von 1,5 bis 2 mg erhalten.
Summary The possibility was investigated of reducing the weight of sample in the micro determination of sulfur by theSchöniger procedure, but without essentially modifying the usual method, namely by using a modified flask. Samples weighing 1.5 to 2 mg gave results within the usual tolerance limits (standard deviation ± 0.13%).
Résumé On a étudié la possibilité de diminuer la prise d'essai dans le mierodosage du soufre suivantSchöniger, sans altérer d'une manière importante le procédé habituel, en utilisant un ballon modifié. Les résultats qui se situent dans les limites de tolérance habituelles (écart-type=± 0,13%) correspondent à des prises, d'essai de 1,5 à 2 mg.相似文献
4.
Cametti M Nissinen M Dalla Cort A Mandolini L Rissanen K 《Chemical communications (Cambridge, England)》2003,(19):2420-2421
Uranyl-salophen complexes endowed with aromatic side arms behave as very efficient ditopic receptors towards tetralkylammonium halides as a result of a combination of Lewis acid-base and cation-pi interactions. 相似文献
5.
Dalla Cort A Mandolini L Palmieri G Pasquini C Schiaffino L 《Chemical communications (Cambridge, England)》2003,(17):2178-2179
In complexes with the uranyl dication salophen ligands are highly puckered. This implies that non-symmetrically substituted uranyl-salophen derivatives exist in principle as a pair of enantiomers. However, due to easy disrotations about the bonds connecting the phenoxide units to the imine carbons, the rate of interconversion between enantiomeric forms of simple, sterically unhindered compounds is extremely fast. Bulky substituents in appropriate positions decrease the interconversion rate and make this novel type of inherent chirality detectable by 1H and 13C NMR. 相似文献
6.
Roberto Consonni Piero Dalla Croce Raffaella Ferraccioli 《Journal of heterocyclic chemistry》1990,27(2):427-431
The 2-methyl-2H-1,2-benzothiazin-4-(3H)-one 1,1 dioxide ( 2 ), obtained according to a new, one-pot method, is transformed into the pyrrolidino enamine 3 . Reaction of p-toluenesulphonyl azide with 3 gives, via an unstable triazoline adduct which loses nitrogen, the two isomeric tosylamino derivatives 4 and 5 . The structures have been assigned by exhaustive nmr analysis and some aspects on their formation and chemical behaviour are discussed. 相似文献
7.
Giampaolo Primofiore Anna Maria Marini Federico Da Settimo Silvia Salerno Daniele Bertini Lisa Dalla Via Sebastiano Marciani Magno 《Journal of heterocyclic chemistry》2003,40(5):783-788
The synthesis of new planar derivatives characterized by the presence of a pyridothiopyranopyrazole or pyridothiopyranopyrimidine nucleus, carrying a substituted aryl group, is reported. The novel 1,4‐dihydropyrido[3′,2′:5,6]thiopyrano[4,3‐c]pyrazole derivatives were obtained by condensation of 2,3‐dihydro‐3‐hydroxymethylenethiopyrano[2,3‐b]pyridin‐4(4H)‐ones with appropriate hydrazines. The preparation of 2‐substituted pyrido[3′,2′:5,6]thiopyrano[4,3‐d]pyrimidines was accomplished from the intermediate 2,3‐dihy‐dro‐3‐dimethylaminomethylenethiopyrano[2,3‐b]pyridin‐4(4H)‐ones by reaction with the appropriate binucleophile amidines. The antiproliferative activity of some new products was tested by an in vitro assay on human tumour cell lines (HL‐60 and HeLa), but none of them showed any significant effects in the tests performed. Accordingly, linear flow dichroism measurements indicated their inability to form a molecular complex with DNA. 相似文献
8.
Piero Dalla Croce Paola Del Buttero Stefano Mayorana Raffaele Vistocco 《Journal of heterocyclic chemistry》1978,15(3):515-517
Thiete 1,1-dioxide reacts with 2 moles of α-chlorobenzalphenylhydrazine and methyl phenylhydrazonochloroacetate in the presence of triethylamine leading to the pyrazole derivatives 6 and 7 whose structure and mechanism of formation are discussed. 相似文献
9.
Dalla Serra M Coraiola M Viero G Comai M Potrich C Ferreras M Baba-Moussa L Colin DA Menestrina G Bhakdi S Prévost G 《Journal of chemical information and modeling》2005,45(6):1539-1545
Staphylococcal gamma-hemolysins are bicomponent toxins forming a protein family with leucocidins and alpha-toxin. Two active toxins (AB and CB) can be formed combining one of the class-S components, HlgA or HlgC, with the class-F component HlgB. These two gamma-hemolysins form pores with marked similarities to alpha-toxin in terms of conductance, nonlinearity of the current-voltage curve, and channel stability in the open state. AB and CB pores, however, are cation-selective, whereas alpha-toxin is anion-selective. gamma-Hemolysins' pores are hetero-oligomers formed by three or four copies of each component (indicated as 3A3B and 3C3B or 4A4B and 4C4B). Point mutants located on a beta-strand of the class-S component that forms part of the protomer-protomer contact region can prevent oligomer assembly. Interestingly, these mutants inhibit growth of pores formed not only by their natural components but also by nonstandard components. This lead to the hypothesis that mixed ABC pores could also be formed. By studying the conductance of pores, assembled in the presence of all three components (in different ratios), it was observed that the magnitudes expected for mixed pores were, indeed, present. We conclude that the gamma-hemolysin/leucocidin bicomponent toxin family may form a larger than expected number of active toxins by cross-combining various S and F components. 相似文献
10.
Lavoro eseguito con il finanziamento del M.P.I. 相似文献