Isotopic Traceability (13C and 18O) of Greek Olive Oil

In recent years, isotopic analysis has been proven a valuable tool for the determination of the origin of various materials. In this article, we studied the ¹⁸O and ¹³C isotopic values of 210 olive oil samples that were originated from different regions in Greece in order to verify how these values are affected by the climate regime. We observed that the δ¹⁸O isotopic values range from 19.2 ‰ to 25.2 ‰ and the δ¹³C values range from −32.7 ‰ to −28.3 ‰. These differences between the olive oils’ isotopic values depended on the regional temperature, the meteoric water, and the distance from the sea. Furthermore, we studied the ¹³C isotopic values of biophenolic extracts, and we observed that they have same capability to differentiate the geographic origin. Finally, we compared the isotopic values of Greek olive oils with samples from Italy, and we concluded that there is a great dependence of oxygen isotopes on the climatic characteristics of the different geographical areas.     

Stereoselective Synthesis of Enantiomerically Pure Nupharamine Alkaloids from Castoreum

An animalic note : The first total synthesis of the all‐cis nupharamine 2 , an alkaloid from beaver castoreum, is based on the stereoselective domino Mannich–Michael reaction of N‐galactosylfurylaldimine to give 1 (Piv=pivaloyl), subsequent conjugate cuprate addition, and stereoselective protonation of the enolate. These reactions are all controlled by the carbohydrate. Protonation of the enolate after cleavage of the auxiliary leads to epimer 3 .

     

"Common synthetic scaffolds" in the synthesis of structurally diverse natural products

Selected natural products have long been considered as desirable targets for total synthesis due to their unique biological properties and their challenging structural complexity. Laboratory synthesis of natural compounds usually relies on target-oriented synthesis, involving the production, isolation and purification of successive intermediates, requiring multiple steps to arrive to the final product. A far more economical approach using common synthetic scaffolds that can be readily transformed through biomimetic-like pathways to a range of structurally diverse natural products has been evolved in the last decade, leading synthesis to new directions. This tutorial review critically presents the hallmarks in this field.     

FDTD analysis of photonic crystal defect layers filled with liquid crystals

Dielectric and metallic photonic crystals comprising nematic liquid crystal materials as defect layers or elements are investigated by the Finite Difference Time Domain (FDTD) method. Appropriate formulations of the FDTD algorithm, for the simulation of anisotropic and dispersive media as well as periodic geometries, are utilised and combined with the proper absorbing and periodic boundary conditions. The spectral properties of the presented structures are tuned by means of applying static electric fields across the defect layers, thus affecting the molecular orientation of the liquid crystal material. Numerical results show that sufficient tuning ranges are achieved, requiring low operating voltages. Moreover, high and sharp resonance peaks are observed.     

An Optimized HPLC-DAD Methodology for the Determination of Anthocyanins in Grape Skins of Red Greek Winegrape Cultivars (Vitis vinifera L.)

A rapid and simple HPLC-DAD analytical method was developed and optimized for the determination of anthocynanins in three red Greek winegrape varieties (Kotsifali, Limnio, and Vradiano). The critical parameters, such as the acidifying solvent and the extraction temperature, which affect the extraction of anthocyanins from the grapes, were studied to find the optimum values. The developed methodology was validated in terms of selectivity, linearity, accuracy, and precision and presented satisfactory results. The limits of quantification (LOQs) ranged between 0.20 mg/kg to 0.60 mg/kg, and the limits of detection (LODs) ranged between 0.06 mg/kg and 0.12 mg/kg. The RSD% of the within-day and between-day assays were lower than 6.2% and 8.5%, respectively, showing adequate precision. The accuracy ranged between 91.6 and 119% for within-day assay and between 89.9 and 123% for between-day assay. Sixteen samples from the main regions of each variety as well as from the official ampelographic collections of Greece were collected during the 2020 growing season and were further analyzed by HPLC-DAD. Notable differences in the anthocyanin content were detected among the cultivars using hierarchical cluster analysis (HCA).     

Boundary crossing through in-service online mathematics teacher education: the case of scenarios and half-baked microworlds

We address online mathematics teacher education as a means of immersing teachers into new kinds of collectives where professional development may be enhanced by crossing the boundaries of their habitual communities and the norms within these. We analyse the ways in which newly trained teacher educators interacted around their designs and productions for in-service courses they were giving to colleagues. We focus on their uses of scenarios and half-baked microworlds as two kinds of artefacts we had designed to play the role of improvable boundary objects. We consider these interactions as a forum for challenge and for professional development through frequent and relevant boundary crossing.