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This paper considers a single machine scheduling problem with the learning effect and multiple availability constraints that minimizes the total completion time. To solve this problem, a new binary integer programming model is presented, and a branch-and-bound algorithm is also developed for solving the given problem optimally. Since the problem is strongly NP-hard, to find the near-optimal solution for large-sized problems within a reasonable time, two meta-heuristics; namely, genetic algorithm and simulated annealing are developed. Finally, the computational results are provided to compare the result of the binary integer programming, branch-and-bound algorithm, genetic algorithm and simulated annealing. Then, the efficiency of the proposed algorithms is discussed.  相似文献   
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