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Opeyemi N. Avoseh Kayode Aremu Benedicta N. Nkeh-Chungag Sandile P. Songca Samuel O. Oluwafemi 《Natural product research》2015,29(12):1184-1188
The volatile oils of the leaves and the stem bark of Acacia mearnsii de Wild obtained by hydro-distillation were analysed by gas chromatography–mass spectrometry. A total of 20, 38, 29 and 38 components accounted for 93.8%, 92.1%, 78.5% and 90.9% of the total oils of the fresh, dry leaves and fresh, dry stem bark, respectively. The major components of the oil were octadecyl alcohol (25.5%) and phytol (10.5%); cis-verbenol (29.5%); phytol (10.1%) and phytol (23.4%) for the fresh leaves, dried leaves, fresh stem, dry stem bark, respectively. Oral administration of essential oils at a dose of 2% showed significant (p < 0.05) anti-inflammatory properties in the albumin-induced test model in rats. Oils from the fresh leaves and dry stems inhibited inflammation beyond 4 h post treatment. The potent anti-inflammatory activity of essential oils of A. mearnsii hereby confirmed its traditional use in treating various inflammatory diseases. 相似文献
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Oluwole S. Aremu Parvesh Singh Moganavelli Singh Chunderika Mocktar Neil A. Koorbanally 《Journal of heterocyclic chemistry》2019,56(11):3008-3016
Chloro, fluoro, and nitro derivatives of 7‐amino‐5‐aryl‐6‐cyano‐5H‐pyrano pyrimidin‐2,4‐diones were produced by reacting malononitrile, barbituric acid, and aromatic aldehydes together with a DABCO catalyst in an aqueous one‐pot reaction. This is the first report of these compounds being synthesized with DABCO as a catalyst, which produced the compounds in yields in excess of 90%. The 2,4‐difluoro derivative ( 11 ) was novel. The structures of the synthesized compounds were elucidated by means of 1H, 13C, and 2D NMR spectroscopy. Compound 2 (2‐Cl derivative) had MBC values of <200μM against both Staphylococcus aureus and MRSA, and the 2‐nitro derivative 5 had an MBC of 191μM against the Gram–ve Escherichia coli. The synthesized compounds were also tested for their anticancer activity against a HeLa cell line, where all the compounds showed better activity (IC50 values between 129μM and 340μM) than 5‐fluorouracil, a commonly known anticancer drug. 相似文献
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Chapatwala Kirit D. Babu G. R. V. Dudley Charles Williams Rita Aremu Kazeem 《Applied biochemistry and biotechnology》1993,(1):655-666
Pseudomonas putida, capable of utilizing acetonitrile as a sole source of carbon and nitrogen, was isolated from contaminated soil and water
samples collected from industrial sites. TheP. putida cells were immobilized in calcium alginate beads. The degradation of acetonitrile by the immobilized cells ofP. putida was investigated. The immobilized cells degraded different concentrations of acetonitrile into ammonia and carbon dioxide.
The effect of aeration on the degradation rate was also studied. Oxygen limitation was suggested in the alginate-immobilized
system. The rate of degradation of acetonitrile increased with increase in the rate of aeration. 相似文献
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Ricerche di Matematica - In this paper, we use the gate condition on two multivalued k-demicontractive mappings to approximate a common solution of a finite family of monotone inclusion problem and... 相似文献
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