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1.
Turky Abdallah Bayoumi Ashraf H. Sherbiny Farag F. El-Adl Khaled Abulkhair Hamada S. 《Molecular diversity》2021,25(1):403-420
Molecular Diversity - The discovery of potent STAT3 inhibitors has gained noteworthy impetus in the last decade. In line with this trend, considering the proven biological importance of... 相似文献
2.
Hassan MO Albarwani S Al Yahyaee S Al Haddabi S Rizwi S Jaffer A Al-Lawati J Cai G Comuzzie AG Bayoumi RA 《Community genetics》2005,8(1):56-60
OBJECTIVE: To establish a suitable human model for the study of the genetics of complex diseases. METHODS: We have selected an Omani Arab population to provide the statistical power required to study the genetics of complex diseases with confidence. This model consists of five multigenerational highly inbred pedigrees, descending from a small number of founders just a few generations ago with environmental homogeneity, restricted geographical distribution, detailed records and well-ascertained and -validated pedigrees. Stringent criteria were adopted for defining the phenotypes of hypertension, diabetes mellitus, dyslipidemias and obesity. The SOLAR genetic software package was used to draw the pedigree structure. RESULTS: Outstanding statistical power to detect susceptibility loci was obtained. CONCLUSIONS: This model represents a large homogeneous human family-based population for the study of genetic and environmental factors contributing to complex diseases. 相似文献
3.
Ezzat Hany G. Bayoumi Ashraf H. Sherbiny Farag F. El-Morsy Ahmed M. Ghiaty Adel Alswah Mohamed Abulkhair Hamada S. 《Molecular diversity》2021,25(1):291-306
Molecular Diversity - Many shreds of evidence have recently correlated A2B receptor antagonism with anticancer activity. Hence, the search for an efficient A2B antagonist may help in the... 相似文献
4.
A. E. Abdel Ghany A. M. A. Hashem H. A. M. Abuzeid A. E. Eid H. A. Bayoumi C. M. Julien 《Ionics》2009,15(1):49-59
Single phase LiCo1 − y
Ni
y
O2 (y = 0.4 and 0.5) with fine particles and high homogeneity was synthesized by “chimie douce” assisted by citric acid as the
polymeric agent and investigated as positive electrodes in rechargeable lithium batteries. The long-range and short-range
structural properties are investigated with experiments including X-ray diffraction (XRD), Fourier transform infrared spectroscopy
(FTIR), and superconducting quantum interference device magnetometry. The physicochemical properties of the powders (crystallinity,
lattice constants, grain size) have been investigated in this composition. The powders adopted the α-NaFeO2 structure as it appeared from XRD and FTIR results. Magnetic measurements shows signal at low temperature attributed to the
magnetic domains in the nanostructure sample from which we estimated that the cation mixing are 3.35 and 4.74% for y = 0.4 and 0.5 in LiCo1 − y
Ni
y
O2, respectively. LiCo0.5Ni0.5O2 cathode yields capacity (135 mAh g−1) compared to LiCo0.6Ni0.4O2 cathode (147 mAh g−1) when discharged to a cutoff voltage of 2.9 V vs. Li/Li+. Lower capacity loss and higher discharge efficiency percentage are observed for the cell of LiCo0.6Ni0.4O2 cathode. 相似文献
5.
Yahia Didane Rocio Ponce Ortiz Jian Zhang Keijyu Aosawa Toshinori Tanisawa Hecham Aboubakr Frédéric Fages Jörg Ackermann Noriyuki Yoshimoto Hugues Brisset Christine Videlot-Ackermann 《Tetrahedron》2012,68(24):4664-4671
Solution and solid-state properties of two new perfluoroalkyl end-substituted analogues of distyryl-bithiophene (CF3-DS2T and diCF3-DS2T) are presented. Vacuum deposited thin films were investigated by atomic force microscopy, X-ray diffraction, and implemented as active layers into organic thin film transistors. While physicochemical measurements in solution suggest a preferential hole injection and transport inside CF3-DS2T and diCF3-DS2T films, electrical measurements performed under high vacuum show that CF3-DS2T behaves as n-type semiconductor while no charge transport was measured in diCF3-DS2T. The results highlighted the importance of substituents on conjugated backbone and on the resulting fine ordering in solid state to control the charge transport. 相似文献
6.
In this paper, we study the relation between the fuzzy separation axioms, which had been introduced by the authors in 2001, and the fuzzy proximity defined by Katsaras in 1980. We study also the relation between our fuzzy separation axioms and the G-compactness defined by Gähler in 1995. Moreover, we show here the relation between these fuzzy separation axioms and the fuzzy uniform structures introduced and studied by Gähler and the first author in 1998. 相似文献
7.
LetN(n) andN
*
(n) denote, respectively, the number of unlabeled and labeledN-free posets withn elements. It is proved thatN(n)=2
n logn+o(n logn) andN
*(n)=22n logn+o(n logn). This is obtained by considering the class ofN-free interval posets which can be easily counted. 相似文献
8.
Abu-Hamdeh Nidal H. Abusorrah Abdullah M. Bayoumi Mohannad M. Oztop Hakan F. Sun Chuan 《Journal of Thermal Analysis and Calorimetry》2021,144(6):2627-2639
Journal of Thermal Analysis and Calorimetry - The natural convection of the oil-NE-PCM/Al2O3 inside the parabolic trough collector is studied. To simulate nanoencapsulate-phase change material... 相似文献
9.
10.
Adel M. Ahmad Hamdoon A. Mohammed Tarek M. Faris Abeer S. Hassan Hebatallah B. Mohamed Mahmoud I. El Dosoky Esam M. Aboubakr 《Molecules (Basel, Switzerland)》2021,26(24)
The study aimed to develop a new glutathione (GSH) oral formulation to enhance the delivery of GSH and counter the nephrotoxicity of the anticancer drug, cyclophosphamide (CP). A nanostructured lipid carrier glutathione formulation (GSH-NLCs) composed of glutathione (500 mg), stearic and oleic acid (300 mg, each), and Tween® 80 (2%, w/v) was prepared through the emulsification-solvent-evaporation technique, which exhibited a 452.4 ± 33.19 nm spheroidal-sized particulate material with narrow particle size distributions, −38.5 ± 1.4 mV zeta potential, and an entrapment efficiency of 79.8 ± 1.9%. The GSH formulation was orally delivered, and biologically tested to ameliorate the CP-induced renal toxicity in a rat model. Detailed renal morphology, before and after the GSH-NLCs administration, including the histopathological examinations, confirmed the ameliorating effects of the prepared glutathione formulation together with its safe oral delivery. CP-induced oxidative stress, superoxide dismutase depletion, elevation of malondialdehyde levels, depletion of Bcl-2 concentration levels, and upregulated NF-KB levels were observed and were controlled within the recommended and near normal/control levels. Additionally, the inflammatory mediator marker, IL-1β, serum levels were marginally normalized by delivery of the GHS-NLCs formulation. Oral administration of the pure glutathione did not exhibit any ameliorating effects on the renal tissues, which suggested that the pure glutathione is reactive and is chemically transformed during the oral delivery, which affected its pharmacological action at the renal site. The protective effects of the GSH-NLCs formulation through its antioxidant and anti-inflammatory effects suggested its prominent role in containing CP-induced renal toxicity and renal tissue damage, together with the possibility of administrating higher doses of the anticancer drug, cyclophosphamide, to achieve higher and effective anticancer action in combination with the GSH-NLCs formulation. 相似文献