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1.
The crystallization of poly(ethylene terephthalate) under uniaxial tensile strain at different extension rates was investigated with optical polarimetry in a temperature range between the glass-transition temperature and the quiescent crystallization temperature. The evolution of the optical properties of the polymer, including the turbidity, birefringence, and dichroism, were monitored simultaneously with the mechanical parameters. To complete the semicrystalline microstructure characterization of the polymer under strain, an online wide-angle X-ray diffraction (WAXD) technique was used in separate experiments, which were performed under the same thermomechanical conditions. For real-time measurements, a high-energy synchrotron radiation source was used. The optical properties provided information about both the crystalline and amorphous phases, whereas the WAXD patterns essentially gave information about the crystalline phase. The two experimental techniques were then used in a complementary way to characterize the semicrystalline microstructure. Significant deviations from the stress-optical rule were found. This was attributed to both transient effects and the appearance of crystallites, which consisted of highly oriented molecular segments that could contribute to the optical anisotropy but not necessarily to the stress. The behavior of the optical dichroism was found to be qualitatively different from that of the birefringence. The latter monotonically increased with the strain, whereas the former first increased with the strain, passed through a maximum, and then decreased to a steady-state value. © 2004 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 42: 1915–1927, 2004 相似文献
2.
Sarra Akermi Slim Smaoui Khaoula Elhadef Mariam Fourati Nacim Louhichi Moufida Chaari Ahlem Chakchouk Mtibaa Aissette Baanannou Saber Masmoudi Lotfi Mellouli 《Molecules (Basel, Switzerland)》2022,27(9)
Nowadays, increasing interest has recently been given to the exploration of new food preservatives to avoid foodborne outbreaks or food spoilage. Likewise, new compounds that substitute the commonly used synthetic food preservatives are required to restrain the rising problem of microbial resistance. Accordingly, the present study was conducted to examine the chemical composition and the mechanism(s) of action of the Cupressus sempervirens essential oil (CSEO) against Salmonella enterica Typhimuriumand Staphyloccocus aureus. The gas chromatography analysis revealed α-pinene (38.47%) and δ-3-carene (25.14%) are the major components of the CSEO. By using computational methods, such as quantitative structure–activity relationship (QSAR), we revealed that many CSEO components had no toxic effects. Moreover, findings indicated that α-pinene, δ-3-carene and borneol, a minor compound of CSEO, could inhibit the AcrB-TolC and MepR efflux pump activity of S. enterica Typhimurium and S. aureus, respectively. In addition, our molecular docking predictions indicated the high affinity of these three compounds with active sites of bacterial DNA and RNA polymerases, pointing to plausible impairments of the pathogenic bacteria cell replication processes. As well, the safety profile was developed through the zebrafish model. The in vivo toxicological evaluation of (CSEO) exhibited a concentration-dependent manner, with a lethal concentration (LC50) equal to 6.6 µg/mL. 相似文献
3.
scar M. Bautista‐Aguilera Lhassane Ismaili Isabel Iriepa Daniel Diez‐Iriepa Fakher Chabchoub Jos Marco‐Contelles Marta Prez 《Chemical record (New York, N.Y.)》2021,21(1):162-174
Herein we have reviewed our recent developments for the identification of new tacrine analogues for Alzheimer's disease (AD) therapy. Tacrine, the first cholinesterase inhibitor approved for AD treatment, did not stop the progression of AD, producing only some cognitive improvements, but exhibited secondary effects mainly due to its hepatotoxicity. Thus, the drug was withdrawn from the clinics administration. Since then, many publications have described non‐hepatotoxic tacrines, and in addition, important efforts have been made to design multitarget tacrines by combining their cholinesterase inhibition profile with the modulation of other biological targets involved in AD. 相似文献
4.
Najahi E Sudor J Chabchoub F Nepveu F Zribi F Duval R 《Molecules (Basel, Switzerland)》2010,15(12):8841-8855
In this paper we present the room temperature synthesis of a novel serie of 1,4-disubstituted-1,2,3-triazoles 4a-l by employing the (3+2) cycloaddition reaction of pyrimidinones containing alkyne functions with different model azides in the presence of copper sulphate and sodium ascorbate. To obtain the final triazoles, we also synthesized the major precursors 6-amino-5-cyano-1,4-disubstituted-2(1H)-pyrimidinones 3a-r from ethyl 2,2-dicyanovinylcarbamate derivatives 2a-c and various primary aromatic amines containing an alkyne group. The triazoles were prepared in good to very good yields. 相似文献
5.
We reinvestigate the sign problem in the two-dimensional Hubbard model using the projector ground state Quantum Monte Carlo scheme with Langevin dynamics. Our interest is mainly motivated by the question: what is the parameter space in which simulations may be performed with reliable results and how does the average sign scales with inverse temperature? In the parameter space in which one may omit the sign problem we have studied the ground state properties: momentum distribution and spin structure. We find an exponential decay of the average sign. At half filling, we find evidence for an antiferromagnetic insulating ground state. At off half band fillings, the antiferromagnetic state is destroyed leaving place to an incommensurate spin density state. 相似文献
6.
Synthesis,Crystal Structure,and Antibacterial Activity of 1,2,4‐Triazoles and 1,2,4‐Triazol‐3‐one
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Bochra Ben Salah Najla Chaari Awatef Rekik Anis Ben Hsouna Mohamed Trigui Mohamed Kossentini 《Journal of heterocyclic chemistry》2015,52(6):1769-1775
A straightforward method has been developed for the synthesis of 1,2,4‐triazol‐3‐one 3 and 1,2,4‐triazoles 6a , 6b , 6c , 6d starting from N1‐substituted‐N1‐tosylhydrazonates 2 and hydrazine monohydrate. This methodology affords a number of 1,2,4‐triazol‐3‐one 3 and 1,2,4‐triazoles 6a , 6b , 6c , 6d in reasonable yields. The structures of all new compounds were elucidated using infrared, 1H and 13C NMR, high‐resolution mass spectrometry, elemental analysis, and the X‐ray crystallography (for compounds 3 and 6a ). Some of the newly synthesized compounds were screened for their antibacterial activity. 相似文献
7.
Kamoun F Fguira IB Hassen NB Mejdoub H Lereclus D Jaoua S 《Applied biochemistry and biotechnology》2011,165(1):300-314
This study reports on the identification, characterization and purification of a new bacteriocin, named Bacthuricin F103,
from a Bacillus thuringiensis strain BUPM103. Bacthuricin F103 production began in the early exponential phase and reached a maximum in the middle of the
same phase. Two chromatographic methods based on high performance liquid chromatography and fast protein liquid chromatography
systems were used to purify Bacthuricin F103. Sodium dodecyl sulphate-polyacrylamide gel electrophoresis revealed that this
bacteriocin had a molecular weight of approximately 11 kDa. It also showed a wide range of thermostability of up to 80 °C
for 60 min and a broad spectrum of antimicrobial activity over a pH range of 3.0–10.0. This bacteriocin was noted, and for
the first time, to exhibit potent antimicrobial activity against Agrobacterium subsp. strains, the major causal agents of crown gall disease in tomato and vineyard crops, and against several challenging
organisms in food, such as Listeria monocytogenes and Bacillus cereus. Complete killing with immediate impact on cells was observed within a short period of time. The sequence obtained for Bacthuricin
F103 by direct N-terminal sequencing shared considerable homology with hemolysin. Bacthuricin F103 was noted to act through
the depletion of intracellular ions, which suggest that the cell membrane was a possible target to Bacthuricin F103. 相似文献
8.
A numerical study of the three-dimensional fluid flow has been carried out to determine the effects of the transverse aspect ratio, Ay, on the flow structure in two-sided non-facing lid-driven cavities. The flow is complex, unstable and can undergo bifurcation. The numerical method is based on the finite volume method and multigrid acceleration. Computations have been investigated for several Reynolds numbers and various aspect ratio values. At a fixed Reynolds number, Re=500, the three-dimensional flow characteristics are analyzed considering four transverse aspect ratios, Ay=1,0.75,0.5 and 0.25. It is observed that the transition to the unsteady regime follows the classical scheme of a Hopf bifurcation. An analysis of the flow evolution shows that, at Ay=0.75, the flow bifurcates to a periodic regime at (Re=600) with a frequency f=0.093 less than the predicted value in the cubical cavity. A correlation is established when Ay=0.5 and gives the critical Reynolds number value. At Ay=0.25, the periodic regime occurs at high Re value beyond 3500, after which the flow becomes chaotic. It is shown that, when increasing Ay over the unit, the flow in the cavity exhibits a complex behavior. The kinetic energy transmission from the driven walls to the cavity center is reduced at low Ay values. 相似文献
9.
A selection of steroids, glycerides, clerodane diterpenoids, and a beta-hydroxy fatty acid methyl ester, all previously isolated from Ajuga pseudoiva leaves, were tested for their antibacterial activity toward three Gram- rods and one Gram+ coccus using the dilution method; MIC values were determined. The results suggested some importance for a free beta-hydroxy group in the fatty acid ester and also in the glycerides and clerodane derivatives; the absolute configurations of the latter, notably at C2, had little influence on activity. 相似文献
10.
Oussama Graja Bacem Zghal Kajetan Dziedziech Fakher Chaari Adam Jablonski Tomasz Barszcz Mohamed Haddar 《Comptes Rendus Mecanique》2019,347(1):49-61
Planetary gearboxes are widely used in industrial machines. They usually work in harsh environments giving rise to damages and high maintenance costs. Condition monitoring is a key action allowing one to detect the presence of such damage ensuring healthy running conditions. The knowledge of the dynamic behavior of such a gearbox can be achieved using modeling tools as a primary step before conditioning the monitoring subject. In addition, modeling a gear set can help in the stage of design in order to optimize physical and geometric parameters of the system. Therefore, in this work, a two-dimensional lumped parameter model is adopted to build all vibration sources. The time-varying mesh stiffness is approximated as a square wave form. A novel mathematical formulation is proposed to model the amplitude modulation phenomenon due to the rotational motion of the planets around the center of the gearbox. Finally, the overall vibration signal is concluded as a summation of all vibration components influenced by the modulation function. 相似文献