新型手性方酸衍生物的合成及催化前手性芳酮的不对称 还原反应

方酸经酯化后与手性氨基醇反应,继而与脂肪胺、硫醇等作用,首次合成了11个新型手性方酰氨基醇配体。研究了它们经原位制成手性恶唑硼烷催化前手性芳酮的不对称还原的性能,得到手性仲醇的化学产率和e.e值分别为88%～98%和42%～81%。新化合物的结构经IR,1^HNMR,MS及元素分析证实,4b的绝对构型经X射线衍射确认。     

新丰中子同位素:186Hf

在兰州重离子加速器(FDUL)上,用60MeV/μ ¹⁸O离子轰击厚天然钨靶,通过多核子转移反应产生¹⁸⁶Hf. 使用放射化学分离技术从钨和反应产物混和物中分离出铪,并由HPGe探测器测量铪样品的活性.观测到了¹⁸⁶Hf的子体¹⁸⁶Ta的737,5keVY射线的增长、衰变行为,结果表明,本实验首次合成并鉴别了新丰中子同位素¹⁸⁶Hf,测得它的半衰期为(2.6±1.2)min.     

Transition dynamics and adaptive synchronization of time-delay interconnected corticothalamic systems via nonlinear control

Nonlinear Dynamics - A modified corticothalamic (MCT) system with multiple delays for epileptic absence seizures is taken as a study object. Synchronization transition dynamics of two time-delay...     

Improving control effects of absence seizures using single-pulse alternately resetting stimulation(SARS) of corticothalamic circuit

Presently, we develop a simplified corticothalamic(SCT) model and propose a single-pulse alternately resetting stimulation(SARS) with sequentially applying anodic(A, "+") or cathodic(C, "-") phase pulses to the thalamic reticular(RE) nuclei,thalamus-cortex(TC) relay nuclei, and cortical excitatory(EX) neurons, respectively.Abatement effects of ACC-SARS of RE, TC, and EX for the 2 Hz–4 Hz spike and wave discharges(SWD) of absence seizures are then concerned. The m∶n on-off ACC-SARS protocol is shown to effectively reduce the SWD with the least current consumption. In particular, when its frequency is out of the 2 Hz–4 Hz SWD dominant rhythm, the desired seizure abatements can be obtained, which can be further improved by our proposed directional steering(DS) stimulation. The dynamical explanations for the SARS induced seizure abatements are lastly given by calculating the averaged mean firing rate(AMFR)of neurons and triggering averaged mean firing rates(TAMFRs) of 2 Hz–4 Hz SWD.     

Regulating absence seizures by tri-phase delay stimulation applied to globus pallidus internal

Applied Mathematics and Mechanics - In this paper, a reduced globus pallidus internal (GPI)-corticothalamic (GCT) model is developed, and a tri-phase delay stimulation (TPDS) with sequentially...     

铪的新同位素:186Hf

利用兰州重离子加速器提供的60MeV/u的¹⁸O离子束轰击天然钨靶,通过奇异的多核子转移反应生成¹⁸⁶Hf.采用快速放射化学分离技术从钨及反应产物的混合物中分离出铪,由高纯锗(HPGe)探测器测量样品的γ活性,观测到了¹⁸⁶Hf的子体¹⁸⁶Taγ活性的生长、衰变行为.由此表明:本实验首次合成并鉴别了重丰中子新核素¹⁸⁶Hf,并测定它的半衰期为(2.6±1.2)min.