芳基吡啶酮腙类化合物的设计、合成及杀菌活性研究

以吡啶二芳酮为分子插件,以嘧菌腙为母体化合物设计并合成了一系列新型芳基吡啶酮腙类化合物.产物结构经~1HNMR、~(13)CNMR及HRMS确认,并采用生长速率法对所有化合物进行了离体抑菌活性测试.结果表明:在浓度为70μmol/L时,大部分化合物对所选8种病菌具有一定的抑制活性,其中2'-甲基乙酰基苯-4,6-二甲氧基嘧啶-2-腙(Ⅲ-3)和2-(2'-((4'-溴-苯基)(3'-氯-吡啶-4'-基)-亚甲基)-肼基)-4,6-二甲氧基嘧啶(Ⅲ-18)对病原菌抑制效果明显高于对照药嘧菌腙.Ⅲ-3对番茄灰霉病菌EC50为22.18μmol/L(嘧菌腙为31.38μmol/L), Ⅲ-18对水稻纹枯病菌EC50小于0.35μmol/L,比对照药嘧菌腙提高了260倍以上.     

Adaptive interaction driven by the learning effect in the spatial prisoner's dilemma

We propose a computing model in which individuals can automatically adjust their interaction intensity with their mentor according to the learning effect. This model is designed to investigate the cooperative dynamics of the spatial prisoner’s dilemma. More specifically, when the cumulative payoff of a learner is more than his reference earning, he will strengthen his interaction with his mentor; otherwise, he will reduce it. The experimental results indicate that this mechanism can improve the ...     

新型Pyrabactin类似物的设计、合成及种子萌发抑制活性

为了开发结构更为稳定的脱落酸脱落酸(ABA)类似物,以Pyrabactin和2',3'-benzo-iso-ABA(iso-Ph ABA)为先导,利用类同合成的策略设计了一类新型的磺酰胺类化合物.以1-四氢萘酮为原料,经过羰基α位的甲基化、苄位氧化、羰基腙化和磺酰胺化四步,合成了13个结构新颖的磺酰胺类化合物,并对磺酰胺化的反应条件进行了探索优化.抑制种子萌发的生测结果表明,在浓度为50μmol·L-1时,目标化合物具有不同程度的抑制活性,其中有5个化合物对拟南芥和莴苣种子萌发的抑制率分别大于50%和40%.该结果对于新型脱落酸类合成植物激素的创制具有一定的借鉴意义.     

Full-transparent zone plates for THz focusing

A full-transparent zone plate(FTZP), which can reuse the wave blocked in the focusing of the Fresnel zone plate(FZP), is proposed to improve the efficiency of terahertz(THz) focusing without aberration. We find that the substrate thickness of the FTZP has a great influence on the focusing intensity, which results from the Fabry–Perot effect. The focusing efficiency of FTZPs could be about twice as high as that of FZPs, but the widths of both focus spots are comparable with the wavelength. The experimental results are in good agreement with the simulation.     

煤矿巷道采空区煤自燃导致的温度变化在线监测研究

采空区煤自燃在矿井火灾中约占70%,50%以上国有煤矿矿井存在煤层自燃发火危险,因此对采空区温度进行在线监测十分重要。一种把煤矿巷道温度变化转变成光纤Bragg光栅波长移位的温度传感器被应用于煤矿巷道的温度检测。根据朱仙庄煤矿巷道煤层分布及煤粉扩散的特点,在煤矿巷道顶部沿巷道方向每隔2m进行分布式安装本安型光纤Bragg光栅温度传感器,实现了对采空区温度实时监测。     

酸度控制的不同MnO2的水热制备及电化学性能

以KMnO4为锰源、CO(NH2)2为还原剂,通过水热反应制备MnO2,考察了体系酸度对产物结构和形貌的影响,应用X-射线衍射、扫描电镜和N2吸-脱附技术对产物进行表征.结果表明,在0～1 mol/L H2 SO4溶液中,制备了颗粒状、球形、纤维状和海胆状MnO2,前两种MnO2为层状结构,后两种MnO2具有隧道结构.海胆状MnO2的比表面积高达95 m2/g.电化学测试结果显示,在0.1 A/g的电流密度下,海胆状MnO2首次放电比容量达到1318.8 mAh/g.恒流充放电140次后,容量保持率为74;.