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1.
de Santana Felipe Silva Gracioso Louise Hase Karolski Bruno dos Passos Galluzzi Baltazar Marcela Mendes Maria Anita do Nascimento Claudio Augusto Oller Perpetuo Elen Aquino 《Applied biochemistry and biotechnology》2019,189(1):103-115
Applied Biochemistry and Biotechnology - The human exposure to bisphenol A (BPA) occurs frequently. Once, this compound was one of the highest volume chemicals produced worldwide and used as a... 相似文献
2.
Tereza C. R. dos Santos Ricardo Q. Aucélio Reinaldo C. Campos 《Mikrochimica acta》2003,142(1-2):63-66
A simple and direct spectrofluorimetric method has been developed for the determination of aluminum using alizarin red PS
(1,2,4-trihydroxy 9,10-anthraquinone-3-sulfonic acid). The method is based on the strong fluorescence (480/564 nm) of Al3+ and alizarin red. Experimental parameters such as pH, concentration of the ligand, ionic strength of the solution, reaction
time and temperature were optimized in order to maximize the analytical signal. Interferences of several ions (anions and
cations) were studied and evaluated. The linear range of the method extends from 3 to 100 μg L−1. Limit of detection (3sb) was 0.9 μg L−1. The method was tested with a silicate certified reference material. Interferences were eliminated by a liquid extraction
with cupferron.
Author for correspondence. E-mail: aucelior@rdc.puc-rio.br
Received September 10, 2002; accepted January 15, 2003
Published online May 5, 2003 相似文献
3.
U. Täuber C.E.M. Carvalho R.F. dos Santos C.G. Carvalhaes C.E. Fellows 《Applied physics. B, Lasers and optics》2007,87(3):475-481
A six level rate equation system was used to investigate the impact of photodepletion to amplified spontaneous emission (ASE)
of intramolecular proton-transfer (IPT) dyes incorporated into polymeric hosts. The model includes the most important transitions
for the normal and tautomer form of the molecule as well as intersystem crossing and triplet–triplet transitions. The experimentally
observed pulse shape as well as photodepletion phenomena, i.e. a first order exponential decay of the ASE intensity and a
shortening in ASE pulse width, have been simulated successfully. Additionally, the model was used to propose an explanation
of the unexpected high photodepletion of proton-transfer dyes in solids. The results show that the emission cross section
and reabsorption cross section of the tautomer form of the molecule are the most important parameter not only for efficiency
but also for photodepletion. The model was tested by comparison with experimental results of 2-(2’-hydroxyphenyl)benzimidazole
in polymethylmethacrylate (PMMA), polystyrene (PS) and a 1:1 alternating copolymer matrix PS-co-PMMA.
PACS 78.45.th; 42.55.Mv; 42.70.Jk 相似文献
4.
A. Kh. Passos Morgado Ya. Pivnik Yu. N. Podil'chuk 《International Applied Mechanics》1995,31(11):865-872
Universidade de Beira Interior, Portugal: and S. P. Timoshenko Institute of Mechanics, National Academy of Sciences of the Ukraine, Kiev. Translated from Prikladnaya Mekhanika, Vol. 31. No. 11, pp. 3–10, November, 1995. 相似文献
5.
L.A. Carvalho dos Santos J. Hounie 《Journal of Mathematical Analysis and Applications》2004,299(2):465-493
We study Hardy spaces on the boundary of a smooth open subset or Rn and prove that they can be defined either through the intrinsic maximal function or through Poisson integrals, yielding identical spaces. This extends to any smooth open subset of Rn results already known for the unit ball. As an application, a characterization of the weak boundary values of functions that belong to holomorphic Hardy spaces is given, which implies an F. and M. Riesz type theorem. 相似文献
6.
Sannomiya M Rodrigues CM Coelho RG dos Santos LC Hiruma-Lima CA Souza Brito AR Vilegas W 《Journal of chromatography. A》2004,1035(1):47-51
The methanolic extract of the leaves of the medicinal plant Byrsonima crassa (Malpighiaceae) contain flavonoids with antioxidant activity. They were separated in a preparative scale using high-speed counter-current chromatography. The optimum solvent system used was composed of a mixture of ethyl acetate-n-propanol-water (140:8:80 (v/v/v)) and led to a successful separation between monoglucosilated flavonoids (quercetin-3-O-alpha-L-arabinoside, quercetin-3-O-beta-D-galactoside) and the biflavonoid amentoflavone in only 3.5 h. The purities of quercetin-3-O-alpha-L-arabinoside (95 mg), quercetin-3-O-beta-D-galactoside (16 mg) and the biflavonoid amentoflavone (114 mg) were all isolated at purity over 95%. Identification was performed by 1H NMR, 13C NMR and UV analyses. 相似文献
7.
Elaine C. Petronilho Murilo M. Pedrote Mayra A. Marques Yulli M. Passos Michelle F. Mota Benjamin Jakobus Gileno dos Santos de Sousa Filipe Pereira da Costa Adriani L. Felix Giulia D. S. Ferretti Fernando P. Almeida Yraima Cordeiro Tuane C. R. G. Vieira Guilherme A. P. de Oliveira Jerson L. Silva 《Chemical science》2021,12(21):7334
Mutant p53 tends to form aggregates with amyloid properties, especially amyloid oligomers inside the nucleus, which are believed to cause oncogenic gain-of-function (GoF). The mechanism of the formation of the aggregates in the nucleus remains uncertain. The present study demonstrated that the DNA-binding domain of p53 (p53C) underwent phase separation (PS) on the pathway to aggregation under various conditions. p53C phase separated in the presence of the crowding agent polyethylene glycol (PEG). Similarly, mutant p53C (M237I and R249S) underwent PS; however, the process evolved to a solid-like phase transition faster than that in the case of wild-type p53C. The data obtained by microscopy of live cells indicated that transfection of mutant full-length p53 into the cells tended to result in PS and phase transition (PT) in the nuclear compartments, which are likely the cause of the GoF effects. Fluorescence recovery after photobleaching (FRAP) experiments revealed liquid characteristics of the condensates in the nucleus. Mutant p53 tended to undergo gel- and solid-like phase transitions in the nucleus and in nuclear bodies demonstrated by slow and incomplete recovery of fluorescence after photobleaching. Polyanions, such as heparin and RNA, were able to modulate PS and PT in vitro. Heparin apparently stabilized the condensates in a gel-like state, and RNA apparently induced a solid-like state of the protein even in the absence of PEG. Conditions that destabilize p53C into a molten globule conformation also produced liquid droplets in the absence of crowding. The disordered transactivation domain (TAD) modulated both phase separation and amyloid aggregation. In summary, our data provide mechanistic insight into the formation of p53 condensates and conditions that may result in the formation of aggregated structures, such as mutant amyloid oligomers, in cancer. The pathway of mutant p53 from liquid droplets to gel-like and solid-like (amyloid) species may be a suitable target for anticancer therapy.Mutant p53 tends to form aggregates with amyloid properties, especially amyloid oligomers inside the nucleus, which are believed to cause oncogenic gain-of-function (GoF). 相似文献
8.
P. R. N. De Souza D. A. G. Aranda J. W. De M. Carneiro C. Da S. B. De Oliveira O. A. C. Antunes F. B. Passos 《International journal of quantum chemistry》2003,92(4):400-411
B3 LYP hybrid functional with LACVP* pseudopotential was applied for the optimization of geometries of complexes resulting from interaction of benzene, pyridine, naphthalene, and quinoline with Ptn (n = 4, 7) clusters. For benzene‐containing complexes, the most stable form corresponds to a bridge adsorption, with benzene undergoing considerable geometric distortions, assuming a boat‐like conformation. C? H bonds are bended upward from the plane of the cluster. C? C bonds stretch, especially when they form π‐complexes with low coordinated Pt atoms. Some arrangements for pyridine complexes involving the N atom of the organic moiety undergo further distortions, apparently preserving a formal C? N π bond. Except for that distortion, the behavior of any heteroaromatic complex is similar to that of benzene in the same arrangement. The quinoline–Pt7 complex can suitably be used for simulation of the cinchonidine (CD) anchorage over Pt. © 2003 Wiley Periodicals, Inc. Int J Quantum Chem, 2003 相似文献
9.
10.
P. Baltazar V. H. Lara G. Córdoba R. Arroyo 《Journal of Sol-Gel Science and Technology》2006,37(2):129-133
Samples of TiO2 doped with 2 and 5 mol% of Cu2+ were prepared by the sol-gel process. Titanium(IV) isopropoxide and copper(II) nitrate were used as precursors. The samples
were prepared as monolithic shapes, dried at 80°C for 72 h and heat treated at various temperatures in the range 200–900°C
for 2 h. The structural transformation and texture of the samples were investigated by X-ray powder diffraction (XRD) and
nitrogen adsorption. Significant changes were observed during the crystallization process; on the one hand, the crystallization
profiles show that crystallization occurs uniformly and is practically insensitive to the dopant concentration, but when the
transformation at a given temperature is followed as a function of time, the rate of the amorphous-anatase transformation
is larger for the sample containing 2 mol% Cu2+. Electron spin resonance (ESR) results show that in this sample there is no segregation of Cu2+ ions. The sample containing 2 mol% of Cu2+ was selected for the kinetic studies and the temperatures selected were 300, 325, 350, 375 and 400°C, which were taken from
the amorphous to anatase crystallization profile. An activation energy of 137 ± 4 kJ/mol for the crystallization process was
estimated from the kinetic data. These results showed that the effect of the open structure present in the TiO2 amorphous phase provides the atomic mobility required for the crystallization. On the other hand, the differences in the
crystallization rate due to the amount of Cu2+ were explained by the segregation of copper ions to the surface of the samples. 相似文献