Multifunctional Lipoamino Acid Derivatives with Potential Biological Activity

This work aims to develop a number of multifunctional derivatives of lipoamino acids, which potentially have different biological activities. To achieve this aim, the hydrophilic-lipophilic balance for a number of cationic amphiphile structures based on L-glutamic acid and short diamines is theoretically calculated. The developed schemes and performed synthesis allowed us to produce preparative sample quantities for further physicochemical and biological tests. The performed calculations, measurements, and experiments on the liposomal dispersions of the synthesized compounds demonstrate the possibility of designing the same type of structures of an amphiphilic nature based on aliphatic amino acid derivatives and diamines, which can be used both in antibacterial therapy and as the delivery vehicles for genetic material.     

A Sensor for the Recognition and Determination of Tryptophan Enantiomers Based on Carbon-Paste Electrode Modified by Enantiomorphic Crystals of Bromotriphenylmethane

Journal of Analytical Chemistry - We developed an enantioselective voltammetric sensor based on a carbon-paste electrode modified by enantiomorphic crystals of bromotriphenylmethane for the...     

Observation of “Dark” Axisymmetric Plasma Modes in a Single Disk of Two-Dimensional Electrons

Ni–Cr–C materials with a high hardness determined by the presence of regions consisting of Cr₃C₂ microrods with a record microhardness reaching 3200 kg/mm² have been obtained. Their self-organization in a powder consisting of Ni, Cr, and carbon microparticles with a high weight percentage occurs in the process of its sintering at a temperature of 1300°C and the subsequent sharp cooling of the resulting alloy. A model has been proposed for the process of formation of such crystal microrods whose characteristics have been determined by hardness measurement, electron microscopy, and microchemical and X-ray diffraction analyses.