Synthesis and Structure of a New Ruthenium(II) Clathrochelate and the Use of a Highly Porous Ceramic Material with an Immobilized Complex in the Oxidative Conversion of Methane

Kinetics and Catalysis - A new ruthenium(II) cage complex with polar terminal groups in the apical substituents has been synthesized; the molecular design of the complex contributes to the...     

Effect of Irradiation Absorbed Dose and Organic Solvent on the Grafting Rate of PVDF-g-PHEMA through Gamma-ray Irradiation in a Homogenous Solution

High Energy Chemistry - Modification of Polyvinylidene fluoride (PVDF) by radiation grafting is a research hotspot in recent years. In this study, the monomer 2-Hydroxyethyl methacrylate (HEMA) was...     

Nonlinear Optical Properties of Novel Metallophthalocyanines

Journal of Applied Spectroscopy - Detailed measurements of nonlinear optical properties and optical limiting for four phthalocyanine (Pc) derivatives (PcCo, PcCu, PcMn, and PcSi) are reported. The...     

Automatic approximation using asymptotically optimal adaptive interpolation

Numerical Algorithms - We present an asymptotic analysis of adaptive methods for Lp approximation of functions f ∈ Cr([a, b]), where $1\le p\le +\infty $ . The methods rely on piecewise...     

On Almost Interval Preserving Linear Operators

Siberian Mathematical Journal - A lattice homomorphism between quasi-Banach lattices is known to be compact if and only if it is a sum of a series of rank one lattice...     

Versatile Near-Infrared Super-Resolution Imaging of Amyloid Fibrils with the Fluorogenic Probe CRANAD-2

CRANAD-2 is a fluorogenic curcumin derivative used for near-infrared detection and imaging in vivo of amyloid aggregates, which are involved in neurodegenerative diseases. We explore the performance of CRANAD-2 in two super-resolution imaging techniques, namely stimulated emission depletion (STED) and single-molecule localization microscopy (SMLM), with markedly different fluorophore requirements. By conveniently adapting the concentration of CRANAD-2, which transiently binds to amyloid fibrils, we show that it performs well in both techniques, achieving a resolution in the range of 45–55 nm. Correlation of SMLM with atomic force microscopy (AFM) validates the resolution of fine features in the reconstructed super-resolved image. The good performance and versatility of CRANAD-2 provides a powerful tool for near-infrared nanoscopic imaging of amyloids in vitro and in vivo.