Crystal structure of methylbis(chloromethyl)phosphine oxide

In the crystal structure of (CH₂C1)₂P(O)CH₃ and the isomorphous crystal structures of (CH₂Br)₂P(O)CH₃ and (CH₂I)₂P(O)CH₃, the molecules of the methylbis(halomethyl)phosphine oxide have an identical trans, gauche conformation.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1526–1528, July, 1991.     

Physiologically active bis(dialkylamides) of phosphoryl-substituted α,ω-dicarboxylic acids

Bis(dialkylamides) of phosphoryl-substituted α,ω-dicarboxylic acids were synthesized and their biological activity was studied.     

Synthesis and biological activity of dialkylamino-substituted phosphine oxides

A series of dialkylamino-substituted phosphine oxides was synthesized and their physiological activity was studied.     

Design of phosphonate analogs of short peptides by “click” chemistry

Methods were developed for the first time for the modification of the natural neuropeptides Ile–Gly–Leu and Leu–Gly–Leu simultaneously with the phosphonate moiety and the triazole ring or solely with the triazole ring by means of click chemistry. All of the peptidomimetics synthesized were isolated as a mixture of diastereomers and were characterized by spectroscopic methods.

     

Catalytic reduction of acetylene in systems based on iron and sulfides

Conclusions The systems [Fe₄S₄ (n-BuS)₄]^2–-Na/Hg and Fe²⁺-S^2–-Na/Hg in methanol catalytically reduce acetylene under mild conditions.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No, 10, pp. 2394–2396, October, 1982.     

Cesium carbonate as a base in the phase transfer alkylation of PH- and CH-acids

The direct halodefluorination of perfluoroacyl fluorides holds considerable interest in both synthetic and theoretical studies. However, the great strength of the C-F bond at the carbonyl carbon atom in comparison with the analogous C-Cl and C-Br hinders such transformations [1, 2]. In the case of iododefluorination, such reactions have not even been reported.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 8, p. 1932, August, 1991.     

Synthesis and Extractive Properties of Dialkylaminomethyl-substituted Dialkylamides of Diphenylphosphinoylacetic Acid

Dialkylamides of diphenylphosphinoylacetic acids, dialkylaminomethyl-substituted by the methylene group, were prepared by means of the Mannich reaction from diphenyl(dialkylcarbamoylmethyl)-phosphine oxides or by reaction of the latter compounds with tetraethylmethylenediamine. Extractive ability of the obtained compounds toward U(VI) and Pd(II) in nitrate media was studied.__________Translated from Zhurnal Obshchei Khimii, Vol. 75, No. 7, 2005, pp. 1111–1117.Original Russian Text Copyright © 2005 by Yarkevich, Turanov, Kharitonov.     

Cesium carbonate as a base in the phase transfer alkylation of PH- and CH-acids

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 8, p. 1933, August, 1991.     

Synthesis of methyl- and dimethyl-substituted ethylene diphosphine dioxides and their complex-forming properties

Alkylation of diphenylphosphonous acid by allyl bromide leads (depending on the reaction conditions) to the formation of both diphenylallylphosphine oxide and diphenylpropenylphosphine oxide. Addition of phosphonous acids to diphenylpro-penylphosphine and diphenyl(2-methyl)propenylphosphine oxides resulted in the formation of a series of methyl- and dimethyl-substituted ethylenediphosphine dioxides. The complex forming ability of diphosphine dioxides with respect to alkali metal cations was studied. It was shown that 1-diphenylphosphinyl-2-methyl-2-dioctylphosphinylpropane (X) has the highest Li/Na selectivity ((Li)/ (Na)=50).Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 8, pp. 1860–1865, August, 1991.     

Synthesis of dimeric 1,3,2λ5-benzoxazaphospholes from phosphinic acid derivatives by silylation/desiloxylation

The reaction of N,N,O-tris(trimethylsilyl)-o-aminophenol with two equivalents of phosphinic chloride yielded dimeric 2,2-disubstituted 1,3,2λ⁵-benzoxazaphospholes and trimethylsilyl phosphinate. The chlorides having the bulk substituents (o-chlorophenyl or tert-butyl) at phosphorus or containing P N and P O bonds (instead of a P C bond) either didn't react at all or reacted to retain the phosphoryl group. Being stable in solution at 20°C, the individual diastereoisomers of dimeric 1,3,2-benzoxazaphospholes were converted upon warming to an equilibrium mixture of isomers. When reacted with another dimer each gave a mixed dimeric compound having two different phosphorus atoms in the molecule.