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1.
Optical Review - This paper demonstrates a method to estimate the depth of a fluorescence object in turbid media using dual-wavelength excited photodynamic diagnosis, to aid in the invasion depth... 相似文献
2.
Hirokazu Nishimura 《International Journal of Theoretical Physics》1995,34(2):211-228
The notion of a manual, introduced and investigated in detail by Foulis, Randall, and their followers, has turned out to be further reaching than its originators had envisaged. Its omnipresence is comparable with the notion of a sheaf, whose significance is well recognized by every pure and applied mathematician. The principal concern of this paper is to give an appropriate vehicle, as general as possible, by which the theory of manuals can be developed. The vehicle is called an orthogonal category, which is akin to the notion of a category with coproducts. Orthogonal categories provide also a new perspective on the notion of a sheaf over a complete Boolean algebra, deepening our comprehension of Boolean mathematics and paving the way to quantum mathematics. 相似文献
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S. Homma-Takeda Y. Nishimura Y. Watanabe H. Imaseki M. Yukawa 《Journal of Radioanalytical and Nuclear Chemistry》2004,259(3):521-525
Stage-specific and age-dependent profiles of zinc, copper, manganese, and selenium in testis were examined in Wistar rats
by both inductively coupled argon plasma-mass spectrometry (ICP-MS) with a microdissection technique and in situ elemental
imaging of micro-PIXE analysis. The young adult animals (10 weeks old) contained higher levels of zinc and manganese in the
seminiferous tubules at stages VII-VIII than stages XI through VI and IX-X and the levels were higher than those of the immature
and old animals. Copper and selenium levels at stages VII-VIII of the young adult animals were also higher than those of the
immature and old animals. In stages VII and VIII, zinc was higher in the central area of the seminiferous epithelium, where
spermatozoa were localized, demonstrating a cell-specific property.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
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Katsunori Nishimura Rie Hidaka Fumitoshi Hirayama Hidetoshi Arima Kaneto Uekama 《Journal of inclusion phenomena and macrocyclic chemistry》2006,54(1-2):85-88
Geometries, electronic properties and NMR-shielding of cucurbit[5]uril, decamethylcucurbit[5]uril, cucurbit[6]uril, cucurbit[7]uril,
and cucurbit[8]uril are investigated with DFT calculations. All molecules are highly symmetrical with a distinct geometric
flexibility. In addition with a characteristic partial charge distribution these findings account for their chemical complex
building ability. 相似文献
7.
I Kitagawa A Matsuda T Nishimura S Hirai I Yoshioka 《Chemical & pharmaceutical bulletin》1967,15(9):1435-1437
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Hanioka N Jinno H Nishimura T Ando M Ozawa S Sawada J 《Biomedical chromatography : BMC》2001,15(5):328-333
A simple and sensitive assay for glucuronidation activity of 7-ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan (CPT-11), in human liver microsomes by high-performance liquid chromatography (HPLC) with fluorescence detection is reported. The method was validated for the determination of SN-38 glucuronide (SN-38G) with respect to specificity, linearity, recovery, stability, precision, accuracy, and limits of detection and quantitation. There was no interference from matrix and non-enzymatic reactions. The calibration curve for SN-38G was linear from 5 to 500 nM. Average recoveries ranged from 98 to 100% in spiked human liver microsome samples, and the SN-38G was stable at 4 degrees C for at least 72 h. The newly developed method was found to be more sensitive and selective than previous methods using thin layer chromatography and HPLC. The limit of quantitation for SN-38G was 5 nM (2.5 pmol/assay). The intra- and inter-day precision and accuracy were less than 7 and 4%, respectively. The intra- and inter-day precision of enzyme assay for UDP-glucuronosyltransferase (UGT) activity toward SN-38 in human liver microsomes was less than 4%. With this improved sensitivity, the kinetics of SN-38 glucuronidation in human liver microsomes could be determined more precisely. Therefore, this method is applicable to in vitro study on the side effects and drug interactions of CPT-11 using small amounts of biological sample. 相似文献