Three-dimensional total synchronous luminescence spectroscopy criteria for discrimination between normal and malignant breast tissues

Specimens of malignant and normal female human breast tissues were analyzed after surgery by means of synchronous luminescence spectroscopy. Measurements were performed in the ranges of excitation wavelengths from 330 to 650 nm and synchronous wavelengths from 30 to 120 nm to obtain ordinary and first derivative three-dimensional total synchronous luminescence spectra (3d-TSLS) of each specimen. Arithmetic mean of these spectra has been calculated for normal and malignant specimens and analyzed to establish criteria for tissue differentiation. Spectral domain volumes (volumes below luminescence intensity surface) and mean spectral slopes have been calculated and also analyzed as tissue discrimination criteria. The obtained results are discussed in view of the possible relevance of synchronous luminescence spectroscopy in discrimination between normal and malignant breast tissue.     

Enhanced Adhesion Properties,Structure and Sintering Mechanism of Hydroxyapatite Coatings Obtained by Plasma Jet Deposition

Plasma Chemistry and Plasma Processing - Hydroxyapatite (HA) coatings were deposited on high purity titanium substrate by atmospheric plasma spraying (APS) with high electric energy input....     

Comparison of Hydroxyapatite/Poly(lactide-co-glycolide) and Hydroxyapatite/Polyethyleneimine Composite Scaffolds in Bone Regeneration of Swine Mandibular Critical Size Defects: In Vivo Study

Reconstruction of jaw bone defects present a significant problem because of specific aesthetic and functional requirements. Although widely used, the transplantation of standard autograft and allograft materials is still associated with significant constraints. Composite scaffolds, combining advantages of biodegradable polymers with bioceramics, have potential to overcome limitations of standard grafts. Polyethyleneimine could be an interesting novel biocompatible polymer for scaffold construction due to its biocompatibility and chemical structure. To date, there have been no in vivo studies assessing biological properties of hydroxyapatite bioceramics scaffold modified with polyethyleneimine. The aim of this study was to evaluate in vivo effects of composite scaffolds of hydroxyapatite ceramics and poly(lactide-co-glycolide) and novel polyethyleneimine on bone repair in swine’s mandibular defects, and to compare them to conventional bone allograft (BioOss). Scaffolds were prepared using the method of polymer foam template in three steps. Pigs, 3 months old, were used and defects were made in the canine, premolar, and molar area of their mandibles. Four months following the surgical procedure, the bone was analyzed using radiological, histological, and gene expression techniques. Hydroxyapatite ceramics/polyethyleneimine composite scaffold demonstrated improved biological behavior compared to conventional allograft in treatment of swine’s mandibular defects, in terms of bone density and bone tissue histological characteristics.     

Magnetic properties of Co2.4Al0.6O4/SiO2 nanocomposite obtained via sol-gel method

Nanocomposite made of 10 wt% of Co_2.4Al_0.6O₄ particles dispersed in an amorphous SiO₂ matrix has been synthesized by a sol-gel method. X-ray diffraction, transmission electron microscopy and magnetic measurements have been used to characterize the properties of nanocomposite. Most of the particles are well crystallized and have an average diameter below 100 nm. Smaller particles with size below 10 nm have also been observed. A large value of the effective magnetic moment per Co²⁺ ion of 5.08 μ_B and negative and the low Curie-Weiss paramagnetic temperature Θ∼−6 K, obtained from the high-temperature susceptibility data, indicate a possible mixing of Co²⁺ and Co³⁺ ions between tetrahedral and octahedral sites of the spinel crystal lattice. The measurements of static and dynamic magnetic susceptibilities have shown that Co_2.4Al_0.6O₄ particles in SiO₂ matrix display a spin glass behavior at low temperatures.