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Magnuss Vircavs Vallija Rone Daina Vircava 《Analytical and bioanalytical chemistry》1994,350(10-11):650-651
Oxidation products of 5-bromo and 2-methylthio-quinoline-8-thiol are used for the quantitative coprecipitation of As(III), Cu(II) and Cd(II) from water solutions in a wide range of acidity. The recovery is >95%. 相似文献
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Jennyfer Andrea Aldana Rone Aparecido De Grandis Heloiza Nicolella Ana Paula Prado Guissoni Iara Squarisi Caroline Arruda 《Natural product research》2020,34(17):2528-2532
AbstractCopaifera langsdorffii L. is one of the most known medicinal species in Brazil. Its leaves are rich in phenolic compounds with potential biological activities as an antioxidant and chelating agent. This paper reports the isolation of four compounds from the hydroalcoholic extract of the leaves of C. langsdorffii and the investigation of their possible cytoprotective effects against heavy metal poisoning. Quercitrin (1), afzelin (2), 3,5-di-O-(3-O-methyl galloyl) quinic acid (3) and 4,5-di-O-(3-O-methyl galloyl) quinic acid (4), were associated with toxic doses of methylmercury and lead and evaluated by Alamar blue cell viability assays in HepG2 and PC12. The compounds displayed significant cytoprotective effect for the HepG2 cell line against both metals. Compounds 1–4 did not protect PC12 cells against methylmercury induced-cytotoxicity, but at lower concentrations, they protected against lead induced-cytotoxicity. The evaluated compounds showed a promising cytoprotection effect against exposure to heavy metals and should be further investigated as protective agents. 相似文献
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