Synthesis and biological properties of novel structural analogs of isothiobarbamine

Russian Chemical Bulletin - Novel structural analogs of isothiobarbamine, which differ from the prototype scaffold by the substituent at position 2 of the pyrimidine heterocycle, were for the first...     

Synthesis and Structure of 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides

1-Alkoxycarbonylmethyl-4-heteryl-2-pyrrolidones were synthesized by alkylation of 4-heteryl-2-pyrrolidones. 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides were prepared through the reaction of N-esters with ammonia. The resulting acetamides of 2-pyrrolidones exhibit nootropic properties, antiarrhythmic and antiischemic activity.     

Single Centers and Dimers of Impurity Holmium Ions in Synthetic Forsterite Crystals: High-Resolution Spectroscopy

Optics and Spectroscopy - High-resolution low-temperature absorption spectra in the region of the 5I8 → 5I7, 6, 5, 4, 5F5 transitions in impurity Ho3+ ions in...     

Synthesis and structure of (het)arylglutamic acids and pyroglutamic acid hydrazides

Hydrochlorides of (2R*,3R*)-3-(het)arylglutamic acid diesters were synthesized by esterification of the corresponding glutamic acids (Glu). Diesters reacted with hydrazine hydrate to give (4R*,5R*)-2-pyrrolidone-5-carboxylic acid hydrazides. Hydrochlorides of glutamic acids diesters were found to exhibit cardioprotective properties against acute and chronic stress myocardial damage.     

Spectroscopic Study of the Hyperfine Structure of Levels of Impurity Ho3+ Ions in Synthetic Forsterite

JETP Letters - A well-resolved hyperfine structure in optical spectra of holmium-doped synthetic forsterite Mg2SiO4 has been detected for the first time. Crystal-field calculations have been...     

3-(Het)arylglutamic acid hydrochlorides: synthesis and structure

Acid hydrolysis of 4-(het)aryl-3,5,5-tris(alkoxycarbonyl)-2-pyrrolidones obtained by the condensation of 1,1-bis(alkoxycarbonyl)ethenes with diethyl acetylaminomalonate leads to (2R*,3R*)-3-(het)arylglutamic acid hydrochlorides.