排序方式: 共有31条查询结果,搜索用时 15 毫秒
1.
Trends in atomic properties are well-established tools for guiding the analysis and discovery of materials. Here, we show how compression can reveal a long sought-after connection between two central chemical concepts – van-der-Waals (vdW) radii and electronegativity – and how these relate to the driving forces behind chemical and physical transformations.Compression is used to derive a long sought-after connection between two central chemical concepts – van-der-Waals (vdW) radii and electronegativity – and how these relate to the driving forces behind chemical and physical transformations. 相似文献
2.
Chongqing Wang Christopher Lambert Maurice Hauser Adrian Deuschmann Dr. Carsten Zeilinger Prof. Dr. Klemens Rottner Prof. Dr. Theresia E. B. Stradal Prof. Dr. Marc Stadler Dr. Elizabeth J. Skellam Prof. Dr. Russell J. Cox 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(60):13578-13583
Mutasynthesis of pyrichalasin H from Magnaporthe grisea NI980 yielded a series of unprecedented 4′-substituted cytochalasin analogues in titres as high as the wild-type system (≈60 mg L−1). Halogenated, O-alkyl, O-allyl and O-propargyl examples were formed, as well as a 4′-azido analogue. 4′-O-Propargyl and 4′-azido analogues reacted smoothly in Huisgen cycloaddition reactions, whereas p-Br and p-I compounds reacted in Pd-catalysed cross-coupling reactions. A series of examples of biotin-linked, dye-linked and dimeric cytochalasins was rapidly created. In vitro and in vivo bioassays of these compounds showed that the 4′-halogenated and azido derivatives retained their cytotoxicity and antifungal activities; but a unique 4′-amino analogue was inactive. Attachment of larger substituents attenuated the bioactivities. In vivo actin-binding studies with adherent mammalian cells showed that actin remains the likely intracellular target. Dye-linked compounds revealed visualisation of intracellular actin structures even in the absence of phalloidin, thus constituting a potential new class of actin-visualisation tools with filament-barbed end-binding specificity. 相似文献
3.
Shyjumon Ibrahimkutty Daniel Issenmann Stefan Schleef Anke‐Susanne Müller Yves‐Laurent Mathis Biliana Gasharova Erhart Huttel Ralph Steininger Jörg Göttlicher Tilo Baumbach Albrecht Bartels Christof Janke Anton Plech 《Journal of synchrotron radiation》2011,18(4):539-545
A high‐repetition‐rate pump–probe experiment is presented, based on the asynchronous sampling approach. The low‐α mode at the synchrotron ANKA can be used for a time resolution down to the picosecond limit for the time‐domain sampling of the coherent THz emission as well as for hard X‐ray pump–probe experiments, which probe structural dynamics in the condensed phase. It is shown that a synchronization of better than 1 ps is achieved, and examples of phonon dynamics of semiconductors are presented. 相似文献
4.
5.
6.
V. A. Ivanshin R. Schauwecker M. Warden P. Erhart H. Keller H. -J. Guentherodt H. P. Lang V. Thommen-Geiser 《Physica C: Superconductivity and its Applications》1996,260(3-4):167-172
Methods of electron-spin resonance (ESR) and direct, non-linear field-modulated microwave absorption (FMMA) were applied for the measurements in low- and high-purity samples of rubidium-doped fullerene, Rb3C60. The coexistence of the normal strong ESR signals and regular series of weak absorption lines similar to those seen in systems of Josephson junctions was observed in the high-purity sample. The possible influence of the vortex lattice on the ESR signals was also studied. We determined from FMMA investigations using the Portis model the critical field μ0H* = 40 μT, the depinning current density Jc*(μ0H0 = 1 mT) 4 × 108 A/m2 in low magnetic field and Jc*(μ0H0 > 100 mT) 1.6 × 108 A/m2 in higher fields. These values were generally one order of magnitude higher than the highest corresponding values previously observed in high-temperature superconductors (HTS's). 相似文献
7.
8.
Martin Müller Theresia Rieser Paul L. Dubin Klaus Lunkwitz 《Macromolecular rapid communications》2001,22(6):390-395
Protein adsorption was studied by in-situ ATR-FT-IR spectroscopy of consecutively deposited polyelectrolyte multilayer systems terminated either with poly(ethyleneimine) (PEI) or polyanions, such as poly-(acrylic acid) (PAC), poly(maleic acid-co-propylene) (PMA-P) or poly(vinyl sulfate) (PVS). The influence of the polyanion type, pH and ionic strength was investigated. Negatively charged human serum albumin (HSA) was strongly repelled by multilayers terminated with weak polyanions (PAC, PMA-P), whereas moderate attraction was observed for those terminated with the strong polyanion PVS. Changing the pH from 7.4 to 5 resulted in enhanced HSA adsorption onto PAC-terminated multilayers. An increase in ionic strength diminished the attractive HSA adsorption onto PEI-terminated multilayers. For the PEI/PAC system, the biomedically relevant adsorption of human fibrinogen (FGN) is determined via its isoelectric point in accordance with three other proteins. 相似文献
9.
10.
Martin Müller Theresia Rieser Klaus Lunkwitz Jochen Meier-Haack 《Macromolecular rapid communications》1999,20(12):607-611
In-situ attenuated total reflection (ATR)-FTIR spectroscopy enabled studies on the interaction between the differently charged model proteins human serum albumin, lysozyme, immunoglobulin G and multilayer assemblies, which were deposited by alternating adsorption of poly(ethyleneimine) and poly(acrylic acid) onto Si crystals. Low adsorbed protein amounts were observed if the top polyelectrolyte layer and the protein were equally charged, whereas enhanced protein adsorption occurred for electrostatic attraction between protein and top polyelectrolyte layer. 相似文献