Reaction of 2-diethylamino-3-diethylaminomethyl-1,3,2-benzoxazaphospholine with hydroxyl-containing compounds

The reaction of 2-diethylamino-3-diethylaminomethyl-1,3,2-benzoxazaphospholine with functionally substituted alcohols and phenols occurs with the cleavage of exocyclic P-N bond followed by N→P migration of the diethylaminomethyl group and formation of imidophosphonate dimers. A similar reaction with polyhydroxy compounds (diethylene glycol, glycerol) results in symmetrical and asymmetrical spirophosphoranes. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 1781–1784, October, 1993.     

Indole derivatives. I.β-(3-indolyl) ketones

A number of -skatyl--substituted acetoacetic esters (ethyl, tert. -butyl, and benzyl) are prepared by treating gramine with sodium derivatives of -substituted acetoacetic esters. When ethyl -alkyl--skatylacetoacetates are heated with dilute alkali, they are split into indole and a substituted acetoacetic ester, while saponification with concentrated alcoholic alkali gives -substituted-(3-indolyl)propionic acids. 3-Skatyl-heptan-2-one can be obtained by pyrolysis of 3-skatyl-3-carbo-tert. -butoxyheptan-2-one, or by hydrogenolysis of 3-skatyl-3-carbobenzoxyheptan-2-one over a palladium catalyst. Alkylation of cycloheptanone and cyclohexanone enamines by gramine gives cyclic-(3-indolyl)ketones, viz., 2-skatylcyclopentanone and 2-skatylcyclohexanone.     

Supersonic flow over a cone with heat release in the neighborhood of the apex

Supersonic flow over a cone mounted in the wake of a spherical source of heat release is investigated. The free-stream nonuniformity generated by the source leads to effective drag reduction.Translated from Izvestiya Rossiiskoi Akademii Nauk, Mekhanika Zhidkosti i Gaza, No.2, pp. 110–114, March–April, 1993.     

Brevicarine from brevicolline

Conclusions The brevicarine obtained by the cleavage of the pyrrolidine ring of brevicolline is identical with the natural alkaloid, which is an additional proof of its structure.Khimiya Prirodnykh Soedinenii, Vol. 5, No. 5, pp. 404–406, 1969     

Some reactions in alkaloids of carex brevicollis

Nitro derivatives of brevicolline, brevicarpine, and methyl- and acetylbrevicarpines have been reduced to the amino compounds with stannous chloride in hydrochloric acid. 6-Aminobrevicolline, which has been isolated and characterized in the form of the benzoyl derivative, has been converted by the Sandmeyer reaction into 6-bromobrevicolline.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 952–953, July, 1973.