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V. A. Zolottsev V. A. Kostin R. A. Novikov Ya. V. Tkachev M. G. Zavialova M. O. Taratynova A. S. Latysheva O. V. Zazulina V. P. Timofeev A. Yu. Misharin 《Russian Chemical Bulletin》2018,67(4):667-681
A general scheme for the synthesis of oxazoline and benzoxazole derivatives of [17(20)E]-21-norpregnene differing in the structure of the steroid moiety as well as amides of 17β-hydroxy-3-oxopregn-4-en-21-oic and 17α-hydroxy-3-oxopregn-4-en-21-oic acids was developed. The scheme involved synthesis of the steroid building blocks (appropriately protected derivatives of pregn-17(20)-en-21-oic, 17β-hydroxypregnan-21-oic, and 17α-hydroxypregnan-21-oic acids) and subsequent transformation of these building blocks into the target compounds. Following the developed scheme, synthesis of new nitrogen-containing steroid derivatives exhibiting antiandrogenic activity was enabled. 相似文献
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Solov’eva A. B. Kur’yanova A. S. Savko M. A. Aksenova N. A. Afanas’evskaya E. V. Zolottsev V. A. Taratynova M. O. Ponomarev G. V. Timashev P. S. 《Russian Journal of Physical Chemistry A, Focus on Chemistry》2018,92(9):1830-1836
Russian Journal of Physical Chemistry A - Solubilization with pluronic F-127 gave water-soluble forms of hydrophobic photosensitizers—steroid derivatives of pyropheophorbide a. Solubilization... 相似文献
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