New synthesis of 2,4-dialkyl(or diaryl)pyrazolo[1,5-a]-1,3,5-triazines

Reactions of monothiodiacylamines or N-aroylthioimidates with 3-aminopyrazoles gave pyrazolo[1,5-a]-1,3,5-triazines in good yields.     

Synthesis and reactions of 2,3-diamino-4(3H)-pyrimidinones and 3-amino-2-hydrazino-4(3H)-pyrimidinones. I

A series of new 2,3-diamino-4-pyrimidinones and 3-amino-2-hydrazino-4-pyrimidinones were synthesized by the reactions of β-ketoesters with amino or diaminoguanidines.     

Reactions of 2,3-diamino-4(3H)-pyrimidinones. II

The reaction of 2,3-diamino-4(3H)-pyrimidinones with α,β-diketones and orthoesters is described.     

Tunable infrared generation in KTA and applications

Noncollinear difference frequency mixing of dye laser and Nd:YAG second harmonic (fundamental) radiation from a commercial laser system is employed for the generation of 2.7–5.3 μm (1.6–1.7 μm) radiations in a flux-grown KTiOAsO₁ crystal. The generated radiation is used to scan the methane absorption in the fundamental (v ₃) and its first overtone (2v ₃) band at pressure 90 torr in a laboratory made single pass gas cell of length 33 cm.     

Suppression of Ethyl Migration in the Synthesis of 2,5-Anhydro-1-Amino-1,4-Dideoxy-3-Thio-D-Threo-Pentitol Hydrochloride,A Key Intermediate for Oral the 1β-Methylcarbapenems

A reproducible synthesis of 2,5-anhydro-1-amino-1,4-dideoxy-3-thio-D-threo-pentitol hydrochloride (2b) via the Staudinger reaction with triethyl phosphite was developed. An unexpected ethyl migration from an oxygen to the nitrogen of iminophosphorane 7 was observed.     

Working group report: Heavy-ion physics and quark-gluon plasma

This is the report of Heavy Ion Physics and Quark-Gluon Plasma at WHEPP-09 which was part of Working Group-4. Discussion and work on some aspects of quark-gluon plasma believed to have created in heavy-ion collisions and in early Universe are reported.     

Cyanovirin-N binding to Manalpha1-2Man functionalized dendrimers

Manalpha1-2Man functionalized G(3) and G(4)-PAMAM dendrimers have been synthesized and characterized by MALDI-TOF MS and NMR spectroscopy. Precipitation assays to assess the binding of the dimannose-functionalized dendrimers to Cyanovirin-N, a HIV-inactivating protein that blocks virus-to-cell fusion through high mannose mediated interactions, are presented.