Reactions of Sulfenyl,Sulfinyl, and Sulfonyl Halides with Conjugated Dienes and Enynes. Synthesis of Unsaturated Sulfides,Sulfoxides, and Sulfones

The reactivities of sulfenyl, sulfinyl, sulfonyl halides in additions to conjugated dienes'enynes, and their derivatives are compared. Despite the fact that all these reactions involve cleavage offormally similar S-Cl bonds, the addition direction and rate depend on the structure of the reactants (dienes and enynes; organosulfur acid chlorides).     

Synthesis of 2-Propargylaminoethanols from α,β-acetylenic aldimines

A method of synthesis of 2-propargylaminoethanols, perspective synthons for a one-pot synthetic technology excluding isolation of unstable prop-2-ynylideneaminoethanols is developed. A number of 2-propargylaminoethanol hydrochloride derivatives are synthesized, and their ¹H and ¹³C NMR spectra were discussed.     

Reaction of aliphatic imines of trimethylsilylpropinal with 8-mercaptoadenine

N9-Alkyl-7-(trimethylsilyl)-9H-[1,3]-thiazino[3,2-e]purine-4,9-diamines were synthesized by reaction of 3-trimethylsilyl-2-propinal alkylimines with 8-mercaptoadenine in anhydrous DMF. DFT quantum-chemical calculations of isomeric forms of one of the reaction products were performed.     

1-aza-1,3-enynes in synthesis of substituted 4H-[1,3]thiazino[3,2-a]benzimidazol-4-ols

Reaction of N-tert-butyl-1-aza-1,3-enynes with symmetrically substituted 2-mercaptobenzimidazoles in water-alcohol solutions afford 4H-[1,3]thiazino[3,2-a]benzimidazol-4-ols. The structure of compounds obtained was proved by the ¹H and ¹³C NMR spectroscopy and X-ray diffraction data.     

Chemiluminescence Determination of Monopersulfuric Acid

A procedure for the chemiluminescence determination of trace amounts of monopersulfuric acid was developed. The procedure is based on the oxidation of luminol with monopersulfuric acid in alkaline solutions. The detection limit is 6 ng/mL.     

Synthesis of 3-pyridin-4-yl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazepines

A method for the synthesis of the previously inaccessible 3-pyridin-4-yl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazepines was developed. The X-Ray diffraction data for 8-tert-butyl-3-pyridin-4-yl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazepine are presented.