A Fast and Simple Screening Method for m-Nisoldipine and Its Related Substances by MEKC

A rapid and simple method has been developed and validated for the determination of m-nisoldipine and its five related substances using micellar electrokinetic capillary chromatography (MEKC). The key factors, including pH, buffer concentration and buffer additive, sodium dodecyl sulfate (SDS) concentration, applied voltage and temperature were systematically investigated in an uncoated fused silica capillary. The total analysis time was less than 9 min. The forced degradation products of m-nisoldipine, which were induced by hydrogen peroxide, acidic and basic conditions, heat and light, were also tested.

     

Spin Squeezing of Superposition

We investigate the mean spin direction, length of mean spin and spin squeezing in a general superposition of a GHZ state and a W state. It is shown that the mean spin direction and spin squeezing parameter are determined by the coefficients of superposition and the relative phase between the GHZ state and the W state; while the length of mean spin is only determined by coefficients of superposition.     

复合酶酶解法提取褐藻糖胶及其结构分析和抗氧化性研究

用正交试验设计法研究了复合酶酶解法提取褐藻糖胶,使用sevage法脱蛋白,经DEAE-Sepharose FF离子交换层析后得到2个组分F1和F2,并分析了2个褐藻糖胶组分的结构,探讨了褐藻糖胶的抗氧化活性.优化提取工艺中褐藻糖胶的多糖质量分数是30.24%,硫酸根质量分数是21.25%.     

机械臂运动路径设计问题

主要运用最优化的思想对机械臂运动路径的设计问题进行了讨论.首先利用空间几何知识,得出了机械臂末端的空间位置与各关节角度间的关系,然后就不同问题进行具体分析后分别建立了最优化模型并设计了相应算法,根据模型和算法并采用逐步缩小搜索范围等方法对各个问题进行了求解.最后,从提高机械臂灵活性和扩大其适用范围方面提出了改进建议.     

Adsorption behaviors of CO<Subscript>2</Subscript> and CH<Subscript>4</Subscript> on zeolites JSR and Na<Subscript>n</Subscript>JSR using the GCMC simulations

The adsorption behaviors of CO₂ and CH₄ on new siliceous zeolites JSR and Na_nJSR (n = 2, 8, 16) were simulated using the Grand Canonical Monte Carlo method. The adsorption isotherms of CO₂ became higher with an increase in the Na⁺ number at a low pressure range (<150 kPa), whereas the isotherms showed a crossover with increasing pressure and the adsorption amount became smaller at a high pressure range (>850 kPa). With an increase in Na⁺ number, the pore volume decreased as the pore space was occupied by increasing Na⁺ ions. Additionally, two energy peaks on the interaction energy curves implied that CO₂ was adsorbed on two active sites. On the other hand, the adsorption amount of CH₄ decreased with an increase in the Na⁺ number and only one energy peak was observed. Adsorption isotherms were well fitted with the Langmuir and Freundlich equations up to 1000 kPa and the adsorption affinity of CO₂ on Na₁₆JSR zeolite was highest. The adsorption capacities of CO₂ in the studied zeolites were up to 38 times higher than those of CH₄. Diffusion constants of CO₂ and CH₄ decreased with an increase in the adsorbed amount and Na⁺ number. Considering the adsorbed amount, adsorption selectivity and affinity, zeolites JSR with a low Na⁺ number (JSR and Na₂JSR) is a good candidate for a pressure swing adsorption in the separation of CO₂/CH₄ mixture whereas JSR zeolites with high Na⁺ ratios (Na₁₆JSR and Na₈JSR) may be a better selection for a vacuum swing adsorption.     

正丙醇/正己烷/水三组分体系萃取小球藻中的脂质

尝试了用正丙醇/正己烷二组分体系和正丙醇/正己烷/水三组分体系来萃取小球藻中的脂质,结果表明:按正丙醇/正己烷/水的添加顺序,三者体积比为7/2/1时,藻油的产率最高6.44%(藻油质量/干藻质量)。该方法和文献中报道的方法相比具有较高的萃取率,而且使用的正己烷及正丙醇具有较低毒性,可以用于实验室中藻油的提取。     

用于同时多层MRI的选择性射频脉冲的优化设计

近年来,为提高磁共振成像（MRI）信号信噪比（SNR）、缩短成像时间,同时多层成像技术受到了极大的关注.为了实现同时多层的选择性激发,现有的多层成像序列大多使用组合射频（RF）脉冲,该脉冲可包含多个独立的幅值相同相位不同的简单脉冲,由于其采用简单的线性叠加方法,该类脉冲射频功率随脉冲数量呈现平方增长,因而应用受限.针对这一问题,基于自旋动力学和优化控制原理,本文提出了一种针对同时多层MRI的选择性射频脉冲的数值优化方法,该方法充分运用射频脉冲的调控机制,获得优化脉冲,并配合层选梯度,可实现任意层厚、层间距、层数的同时高效选择性激发.最后,通过数字模体的同时多层模拟成像实验验证了优化脉冲的有效性.     

Tripartite Controlled Teleportation via a Seven-Qubit Entangled State

We demonstrate that a seven-qubit entangled state can be used to realize the deterministic tripartite controlled teleportation by performing Bell-state measurements, where Alice wants to teleport an arbitrary single-qubit state of qubit a to Bob, Charlie wants to teleport an arbitrary single-qubit state of qubit b to David and at the same time Edison wants to teleport an arbitrary single-qubit state of qubit c to Ford via the control of the supervisor Tom.     

小车运动二次加速现象的探究

在以气球喷气推动小车运动的物理实验设计教学的过程中,小车出现二次加速现象.经过研究.找到了产生二次加速现象的原因,此外又提出了"用2个相同气球充气后使其大小不同,将其用吸管连通"的实验,其实验结果和理论分析相符.     

高效液相色谱-串联质谱法检测配合饲料中11种蛋白同化激素含量

建立了快速分析配合饲料中睾酮、甲基睾酮、勃地龙、美雄酮、雄烯二酮、脱氢异雄酮、诺龙、丙酸诺龙、司坦唑醇、美伦孕酮、黄体酮11种蛋白同化激素的高效液相色谱-串联质谱(HPLC-MS/MS)法。样品采用乙腈提取,经PSA粉净化后上机测定。采用Phenomenex C₁₈(100 mm×2.1 mm,2.6μm)色谱柱,以0.01%甲酸溶液-乙腈作为流动相进行梯度洗脱,电喷雾离子源正离子模式检测,同位素内标法定量。结果表明,11种蛋白同化激素的线性范围为1～100 ng/mL,相关系数均为0.999,检出限为20μg/kg,定量下限为50μg/kg。50、250、500μg/kg加标水平下,鸡配合饲料中各蛋白同化激素的回收率为94.5%～111%,日内相对标准偏差(RSD)和日间RSD均不大于13%;猪配合饲料中各蛋白同化激素的回收率为90.1%～109%,日内RSD不大于9.0%,日间RSD不大于8.8%。实际样品中检出睾酮和勃地龙,含量分别为9.09～14.68 mg/kg和1.22～1.84 mg/kg。该方法可为饲料中蛋白同化激素的滥用监管提供技术支撑。