全文获取类型
收费全文 | 718篇 |
免费 | 19篇 |
国内免费 | 2篇 |
专业分类
化学 | 574篇 |
晶体学 | 3篇 |
力学 | 10篇 |
数学 | 87篇 |
物理学 | 65篇 |
出版年
2023年 | 3篇 |
2022年 | 10篇 |
2021年 | 10篇 |
2020年 | 12篇 |
2019年 | 13篇 |
2018年 | 3篇 |
2017年 | 9篇 |
2016年 | 6篇 |
2015年 | 18篇 |
2014年 | 16篇 |
2013年 | 32篇 |
2012年 | 42篇 |
2011年 | 41篇 |
2010年 | 18篇 |
2009年 | 28篇 |
2008年 | 37篇 |
2007年 | 54篇 |
2006年 | 33篇 |
2005年 | 50篇 |
2004年 | 30篇 |
2003年 | 36篇 |
2002年 | 36篇 |
2001年 | 11篇 |
2000年 | 9篇 |
1999年 | 7篇 |
1998年 | 7篇 |
1997年 | 5篇 |
1996年 | 15篇 |
1995年 | 9篇 |
1994年 | 4篇 |
1993年 | 9篇 |
1992年 | 6篇 |
1991年 | 4篇 |
1990年 | 5篇 |
1989年 | 8篇 |
1987年 | 4篇 |
1986年 | 3篇 |
1985年 | 5篇 |
1984年 | 6篇 |
1983年 | 7篇 |
1982年 | 7篇 |
1981年 | 6篇 |
1980年 | 6篇 |
1979年 | 13篇 |
1978年 | 3篇 |
1977年 | 3篇 |
1976年 | 5篇 |
1975年 | 4篇 |
1934年 | 3篇 |
1889年 | 2篇 |
排序方式: 共有739条查询结果,搜索用时 15 毫秒
1.
Kristin Fischer Silvio Prause Stefan Spange Frank Cichos Christian Von Borczyskowski 《Journal of Polymer Science.Polymer Physics》2003,41(11):1210-1218
Solvent‐dependent ultraviolet–visible (UV–vis) absorption and Stokes shifts including strong hydrogen‐bond‐donating (HBD) solvents such as 2,2,2‐trifluoroethanol and 1,1,1,3,3,3‐hexafluoro‐2‐propanol of two coumarine dyes (Co 151 and Co 153) were analyzed with multiple‐square analyses of linear solvation energy relationships and the Kamlet–Taft solvent parameter set to α (HBD capacity), β (hydrogen‐bond‐accepting capacity), and π* (dipolarity/polarizability). The UV–vis absorption and emission spectra of Co 151 and Co 153 were measured when adsorbed on various polysaccharides such as different cellulose batches, carboxymethylcelluloses with different degrees of substitution, and chitine. As a result of this evaluation, Co 153 is recommended as an alternative UV–vis probe for evaluating the dipolarity/polarizability of cellulose and cellulose derivates. Multiple adsorption of Co 153 on Linters cellulose took place indicating a wide‐surface polarity distribution, which makes the determination of a rigid polarity parameter questionable. Thus, fluorescence measurements of adsorbed Co 153 are suitable to detect inhomogenities on a surface but not for the determination of empirical polarity parameters. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 41: 1210–1218, 2003 相似文献
2.
The hexasubstituted benzenes 7 and 9b were synthesized starting from 3 and 8b, respectively. In the crystal, 9b adopts the fully alternated conformation with all arylmethyl groups oriented syn. 相似文献
3.
Thierry Wesley de Albuquerque Aguiar Jos Josenildo Batista Silvio Assis de Oliveira Ferreira Maíra de Vasconcelos Lima Sampaio Dewson Rocha Pereira Magda Rhayanny Assuno Ferreira Luiz Alberto Lira Soares Ana Maria Mendona de Albuquerque Melo Mnica Camelo Pessoa de Azevedo Albuquerque Andr de Lima Aires Hallysson Douglas Andrade de Araújo Luana Cassandra Breitenbach Barroso Coelho 《Molecules (Basel, Switzerland)》2022,27(15)
Biomphalaria glabrata snails constitute the main vector of schistosomiasis in Brazil, and Bauhinia monandra Kurz, the leaves of which contain BmoLL lectin with biocidal action, is a plant widely found on continents in which the disease is endemic. This work describes the composition of B. monandra preparations and the effect on embryos and adult snails, their reproduction parameters and hemocytes. We also describe the results of a comet assay after B. glabrata exposure to sublethal concentrations of the preparations. Additionally, the effects of the preparations on S. mansoni cercariae and environmental monitoring with Artemia salina are described. In the chemical evaluation, cinnamic, flavonoid and saponin derivatives were detected in the two preparations assessed, namely the saline extract and the fraction. Both preparations were toxic to embryos in the blastula, gastrula, trochophore, veliger and hippo stages (LC50 of 0.042 and 0.0478; 0.0417 and 0.0419; 0.0897 and 0.1582; 0.3734 and 0.0974; 0.397 and 0.0970 mg/mL, respectively) and to adult snails (LC50 of 6.6 and 0.87 mg/mL, respectively), which were reproductively affected with decreased egg deposition. In blood cell analysis, characteristic cells for apoptosis, micronucleus and binucleation were detected, while for comet analysis, different degrees of nuclear damage were detected. The fraction was able to cause total mortality of the cercariae and did not present environmental toxicity. Therefore, B. monandra preparations are promising in combating schistosomiasis since they can control both the intermediate host and eliminate the infectious agent, besides being safe to the environment. 相似文献
4.
11B and 27Al nuclear magnetic resonances (NMR) in glasses of the NABAL system Na2OB2O3Al2O3 have been studied as a function of composition. From the boron data, the fraction of four-coordinated BO4 units has been determined via computer analysis of the NMR spectra; the method is similar to that employed previously for binary and other ternary borate glasses. The 27Al NMR indicates no abrupt change in the average aluminum environment. Certain linear relationships have been found which yield detailed information on the competing processes of BO3, BO4 and AlO4 formation, and the formation of triclusters consisting of three tetrahedra having one oxygen in common. Furthermore, it is concluded that the oxygen available for the formation of various aluminum-containing species is a function of the soda concentration only and that the conversion to AlO4 is favored as compared with BO4. 相似文献
5.
Erika Cerutti Annelaure Damont Frédéric Dollé Simona Baroni Silvio Aime 《Magnetic resonance in chemistry : MRC》2013,51(2):116-122
DPA‐713 is the lead compound of a recently reported pyrazolo[1,5‐a]pyrimidineacetamide series, targeting the translocator protein (TSPO 18 kDa), and as such, this structure, as well as closely related derivatives, have been already successfully used as positron emission tomography radioligands. On the basis of the pharmacological core of this ligands series, a new magnetic resonance imaging probe, coded DPA‐C6‐(Gd)DOTAMA was designed and successfully synthesized in six steps and 13% overall yield from DPA‐713. The Gd‐DOTA monoamide cage (DOTA = 1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid) represents the magnetic resonance imaging reporter, which is spaced from the phenylpyrazolo[1,5‐a]pyrimidineacetamide moiety (DPA‐713 motif) by a six carbon‐atom chain. DPA‐C6‐(Gd)DOTAMA relaxometric characterization showed the typical behavior of a small‐sized molecule (relaxivity value: 6.02 mM?1 s?1 at 20 MHz). The good hydrophilicity of the metal chelate makes DPA‐C6‐(Gd)DOTAMA soluble in water, affecting thus its biodistribution with respect to the parent lipophilic DPA‐713 molecule. For this reason, it was deemed of interest to load the probe to a large carrier in order to increase its residence lifetime in blood. Whereas DPA‐C6‐(Gd)DOTAMA binds to serum albumin with a low affinity constant, it can be entrapped into liposomes (both in the membrane and in the inner aqueous cavity). The stability of the supramolecular adduct formed by the Gd‐complex and liposomes was assessed by a competition test with albumin. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
6.
Dutz H Helbing K Krimmer J Speckner T Zeitler G Ahrens J Altieri S Annand JR Anton G Arends HJ Beck R Bock A Bradtke C Braghieri A v Drachenfels W Frommberger F Godo M Goertz S Grabmayr P Hasegawa S Hansen K Harmsen J Heid E Hillert W Holvoet H Horikawa N Iwata T Van Hoorebeke L d'Hose N Jennewein P Kiel B Klein F Kondratiev R Lang M Lannoy B Leukel R Lisin V Menze D Meyer W Michel T Naumann J Panzeri A Pedroni P Pinelli T Preobrajenski I Radtke E Reicherz G Rohlof C Rostomyan T Sauer M 《Physical review letters》2003,91(19):192001
To verify the fundamental Gerasimov-Drell-Hearn (GDH) sum rule for the first time experimentally, we measured the helicity dependent total photoabsorption cross section with circularly polarized real photons and longitudinally polarized nucleons in the photon energy range 0.68-1.82 GeV with the tagged photon facility at ELSA. The experiment was carried out with a 4pi detection system, a circularly polarized tagged photon beam, and a frozen spin polarized proton target. The contribution to the GDH sum rule in this photon energy range is [49.9+/-2.4(stat)+/-2.2(syst)] microb. 相似文献
7.
Silvio P. Sorella 《Communications in Mathematical Physics》1993,157(2):231-243
A new way of solving the descent equations corresponding to the Wess-Zumino consistency conditions is presented. The method relies on the introduction of an operator which allows to decompose the exterior space-time derivatived as a BRS commutator. The case of the Yang-Mills theories is treated in detail.Supported in part by the Swiss National Science Foundation 相似文献
8.
K. Büchler K. H. Althoff G. Anton J. Arends W. Beulertz M. Breuer P. Detemple H. Dutz E. Kohlgarth D. Krmer W. Meyer G. Nldeke W. Schneider W. Thiel B. Zucht 《Nuclear Physics A》1994,570(3-4):580-598
The differential cross section of the reaction γp→π+n has been measured with the PHOENICS detector at ELSA in Bonn. For the first time this cross section has been determined simultaneously over a large range of photon energies (Eγ = 220−900 MeV) and pion angles (Θc.m.pi = 35°−135°) with a tagged photon facility. The experimental set-up allowed a considerable kinematic overdetermination of the investigated reaction. Accordingly, the background contributions have been suppressed to below 1%. The measured differential cross section is in good agreement with existing data. The comparison with different model calculations is presented. 相似文献
9.
10.
Angelo Scarciglia Enza Di Gregorio Silvio Aime Giuseppe Ferrauto 《Molecules (Basel, Switzerland)》2022,27(8)
8-Hydroxypyrene-1,3,6-trisulfonate (HPTS) is a small, hydrophilic fluorescent molecule. Since the pKa of the hydroxyl group is close to neutrality and quickly responds to pH changes, it is widely used as a pH-reporter in cell biology for measurements of intracellular pH. HPTS fluorescence (both excitation and emission spectra) at variable pH was measured in pure water in the presence of NaCl solution or in the presence of different buffers (PBS or hepes in the presence or not of NaCl) and in a solution containing BSA. pKa values have been obtained from the sigmoidal curves. Herein, we investigated the effect of mono-, di-, and trivalent cations (Na+, Ca2+, La3+, Gd3+) on fluorescence changes and proposed its use for the quantification of trivalent cations (e.g., gadolinium ions) present in solution as acqua-ions. Starting from the linear regression, the LoD value of 6.32 µM for the Gd3+ detection was calculated. The effects on the emission were also analyzed in the presence of a combination of Gd3+ at two different concentrations and the previously indicated mono and di-valent ions. The study demonstrated the feasibility of a qualitative method to investigate the intracellular Gd3+ release upon the administration of Gd-based contrast agents in murine macrophages. 相似文献