全文获取类型
收费全文 | 770篇 |
免费 | 24篇 |
国内免费 | 2篇 |
专业分类
化学 | 523篇 |
晶体学 | 7篇 |
力学 | 45篇 |
数学 | 22篇 |
物理学 | 199篇 |
出版年
2023年 | 7篇 |
2022年 | 9篇 |
2021年 | 15篇 |
2020年 | 15篇 |
2019年 | 17篇 |
2018年 | 11篇 |
2017年 | 13篇 |
2016年 | 20篇 |
2015年 | 16篇 |
2014年 | 20篇 |
2013年 | 40篇 |
2012年 | 41篇 |
2011年 | 39篇 |
2010年 | 15篇 |
2009年 | 26篇 |
2008年 | 40篇 |
2007年 | 37篇 |
2006年 | 42篇 |
2005年 | 34篇 |
2004年 | 24篇 |
2003年 | 17篇 |
2002年 | 25篇 |
2001年 | 22篇 |
2000年 | 18篇 |
1999年 | 5篇 |
1998年 | 7篇 |
1996年 | 10篇 |
1995年 | 6篇 |
1994年 | 10篇 |
1993年 | 8篇 |
1992年 | 11篇 |
1991年 | 9篇 |
1990年 | 7篇 |
1989年 | 7篇 |
1988年 | 8篇 |
1987年 | 11篇 |
1986年 | 9篇 |
1985年 | 5篇 |
1984年 | 10篇 |
1983年 | 7篇 |
1982年 | 8篇 |
1981年 | 5篇 |
1980年 | 9篇 |
1979年 | 10篇 |
1978年 | 11篇 |
1977年 | 6篇 |
1976年 | 7篇 |
1975年 | 9篇 |
1972年 | 5篇 |
1967年 | 5篇 |
排序方式: 共有796条查询结果,搜索用时 0 毫秒
1.
Dr. Christopher R. Opie Dr. Hidetoshi Noda Prof. Dr. Masakatsu Shibasaki Dr. Naoya Kumagai 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(18):4648-4653
The B3NO2 six-membered heterocycle (1,3-dioxa-5-aza-2,4,6-triborinane=DATB), comprising three different non-carbon period 2 elements, has been recently demonstrated to be a powerful catalyst for dehydrative condensation of carboxylic acids and amines. The tedious synthesis of DATB, however, has significantly diminished its utility as a catalyst, and thus the inherent chemical properties of the ring system have remained virtually unexplored. Here, a general and facile synthetic strategy that harnesses a pyrimidine-containing scaffold for the reliable installation of boron atoms is disclosed, giving rise to a series of Pym-DATBs from inexpensive materials in a modular fashion. The identification of a soluble Pym-DATB derivative allowed for the investigation of the dynamic nature of the B3NO2 ring system, revealing differential ring-closing and -opening behaviors depending on the medium. Readily accessible Pym-DATBs proved their utility as efficient catalysts for dehydrative amidation with broad substrate scope and functional-group tolerance, offering a general and practical catalytic alternative to reagent-driven amidation. 相似文献
2.
Akira Yanagisawa Prof. Dr. Takahiro Suzuki Takanori Koide Shogo Okitsu Takayoshi Arai Prof. Dr. 《化学:亚洲杂志》2008,3(10):1793-1800
A Barbier‐type regioselective propargylation of aldehydes and ketones with (3‐bromobut‐1‐ynyl)trimethylsilane has been achieved using reactive barium as a low‐valent metal in THF. Especially in the case of ketones, the corresponding homopropargylic alcohols form almost exclusively. In the reaction of α,β‐unsaturated carbonyl compounds, only 1,2‐adducts have been observed. This method is also applicable to propargylation of imines, and the corresponding homopropargylic amines are obtained regiospecifically in good yields with diastereomeric ratios of up to 87:13. 相似文献
3.
4.
Both S-(-)- and R-(+)-enantiomers of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH), a main oxidative metabolite of the achiral antiepileptic drug phenytoin, could be determined simply, sensitively and accurately using reversed phase high-performance liquid chromatography by using a methanol-monopotassium phosphate eluent containing beta-cyclodextrin. Using this assay procedure, it was determined that an S-(-)-enantiomer was formed predominantly by the oxidation of phenytoin in isolated rat hepatocytes. 相似文献
5.
Summary Thermopiezoelastic materials have recently attracted considerable attention because of their potential use in intelligent
or smart structural systems. The governing equations of a thermopiezoelastic medium are more complex due to the intrinsic
coupling effects that take place among mechanical, electrical and thermal fields. In this analysis, we deal with the problem
of a crack in a semi-infinite, transversely isotropic, thermopiezoelastic material by means of potential functions and Fourier
transforms under steady heat-flux loading conditions. The problem is reduced to a singular integral equation that is solved.
The thermal stress intensity factor for a crack situated in a cadmium selenide material is calculated.
Received 20 March 2001; accepted for publication 18 October 2001 相似文献
6.
Tetsuya Noda 《European Polymer Journal》2007,43(6):2321-2330
Continuous ATRP of MMA was carried out in a flow tubular reactor with varying flow rate, temperature, and [monomer]/[initiator] ratios. Changing the flow rate directly relates to the reaction time. This process produces polymer continuously with the conversion increasing with decreasing flow rate. The molecular weight (relating to the flow rate) increases linearly with conversion which is also observed when the [monomer]/[initiator] ratio was changed. The effect of altering the reaction temperature was studied and the apparent activation energy of the propagation reaction of MMA in this system was calculated to be ∼56.9 kJ mol−1, close to the values reported previously. Preparation of diblock copolymers is also reported with varying comonomers and the conversion, and SEC results suggested that this continuous system is an excellent and facile way to have a continuous ATRP process. 相似文献
7.
N Fujii T Watanabe A Otaka K Bessho I Yamamoto T Noda H Yajima 《Chemical & pharmaceutical bulletin》1987,35(12):4769-4776
8.
9.
Caffeine concentration in human sweat was estimated by measuring separately the amounts of water and caffeine. After washing a finger with tap water for 15 s and waiting 2 min for drying, 70 microL aqueous ethanol solution in a small vial (0.6 mL) was used to sample for several minutes. Then 3 microL of the aliquot was used for GC/MS analysis of caffeine. As a first-order relationship between the sweat amount secreted on the left and right hands was obtained (correlation factor 0.848), the amount of sweat secretion during sampling on one hand was estimated by the value obtained on the other hand. This new indirect evaluation was used for the estimation of the amount of sweat secreted during sampling. Typical variations of caffeine concentration in sweat were demonstrated. Thirty minutes after the intake of caffeine, it was secreted in sweat, and the secretion had continued for more than 4 h. 相似文献
10.
An orally applicable pulsatile drug delivery system in dry-coated tablet form was prepared using diltiazem hydrochloride as the model drug, and a polyvinyl chloride-hydrogenated castor oil-polyethyleneglycol mixture as the outer shell of the tablet. In vitro drug release from the prepared tablet exhibited a typical pulsatile pattern with a 7 h lag phase (non-drug release period). This dosage form was orally administered to three beagle dogs under non-fasting and fasting conditions, and the plasma concentration level of diltiazem was determined according to time after administration. The result of the in vivo study in non-fasting dogs suggested that the drug could be released in the gastrointestinal tract as in the in vitro test. However, under the fasting condition, a large difference in the plasma concentration profile was found, suggesting that the disintegration time of the tablet tended to be influenced by the feeding condition of subject. 相似文献