STUDY ON THE ADSORPTION OF OXIDATION OF CROSSLINKED β—CYCLODEXTRIN AND ITS CXOMPOSITE ADSORBENT WITH DIALYTIC MEMBRANE

An urea adsorbent with an aldo structure was obtained by the oxidation of a crosslinked β-cyclodextrin polymer.The highest urea adsorption capacity reached 56.7mg/g in 0.05Maqueous phosphate buffer 37℃ and pH=7.4,and decrease to 4.8mg/g in in aqueous human serum albumin.The composite adsorbent was prepared by the oxidation of a crosslinked β-cyclodextrin and dialytic membrane.It was found that the composite adsorbent has a higher urea adsorption selectivity and capacity compared to that of the oxidation of a crosslinked β-cyclodextrin adsorbent when urea is in aqueous human serum albumin.