Enantioselective total synthesis of polyoxygenated cyclohexanoids: (+)-streptol, ent-RKTS-33 and putative ‘(+)-parasitenone’. Identity of parasitenone with (+)-epoxydon

Short, simple and enantioselective syntheses of the natural product (+)-streptol, the non-peptide apoptosis inhibitor ent-RKTS-33 and the putative structure of ‘parasitenone’ have been accomplished from the readily available chiral building block. ‘Parasitenone’ has been shown to be identical with the known natural product epoxydon.     

A Simple TLC Method for Analysis of Fluconazole in Pharmaceutical Dosage Forms

JPC – Journal of Planar Chromatography – Modern TLC - Use of an internal standard is proposed in this thin-layer chromatographic determination of fluconazole in tablet and capsule...     

Beyond the standard model: Working group report

This report summarises the activities of the working group on ‘Physics beyond the Standard Model’. The results of investigations in incorporatingR-parity in grand unification, the possibility of a light charged Higgs boson in extension of MSSM and radiative generation of neutral vector boson self-couplings within the MSSM are described. Also given is an account of activities in neutrino physics, namely a proposal for a study of the atmospheric muon anomaly in deep underground mines, a field theoretic study of neutrino oscillations and a mechanism to generate appropriate masses of three active plus one sterile neutrino species.     

Extraction chromatographic separation of platinum(IV) from real samples and associated elements

 The extraction behavior of platinum(IV) was studied with N-n-octylaniline as a function of different parameters, such as pH, concentrations of weak acids, mineral acids, reagents and elution time. A selective method was developed for the extraction chromatographic studies of platinum(IV) and its separation from several metal ions with N-n-octylaniline (liquid anion exchanger) as a stationary phase on silica gel. The quantitative extraction of platinum(IV) was observed with 0.067 mol/L N-n-octylaniline and 0.015 mol/L ascorbic acid at pH 1.0. Metal ion was stripped from the column with water and determined spectrophotometrically with stannous chloride method. The proposed method is free from the interference of a large number of cations and anions. Platinum(IV) was separated from pharmaceutical preparations, alloys and synthetic mixtures. Mutual separation scheme was developed for platinum(IV), palladium(II) and gold(III). The log-log plot of N-n-octylaniline concentration versus the distribution ratio indicates that the probable extracted species is ［RR′NH+2 ］· Pt(C6H7O6)－3.     

A general two-term recurrence and its solution

We find a general explicit formula for all sequences satisfying a two-term recurrence of a certain kind. This generalizes familiar formulas for the Stirling and Lah numbers.     

On the spectral problem for anyons

We consider the spectral problem resulting from the Schrödinger equation for a quantum system ofn2 indistinguishable, spinless, hard-core particles on a domain in two dimensional Euclidian space. For particles obeying fractional statistics, and interacting via a repulsive hard core potential, we provide a rigorous framework for analysing the spectral problem with its multi-valued wave functions.Partially supported by the Mathematical Sciences Research Institute, Berkeley California, under NSF Grant # DMS 8505550Partially supported under NSF Grant no. DMR-9101542     

Tetrabutylammonium hydrogen sulfate mediated domino reaction: synthesis of novel benzopyran-annulated pyrano[2,3-c]pyrazoles

A tetrabutylammonium hydrogen sulfate (TBA-HS) mediated procedure for one pot synthesis of novel benzopyran-annulated pyrano[2,3-c]pyrazoles via domino/Knoevenagel-hetero-Diels-Alder reaction has been demonstrated.