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Methods for the incorporation of non-natural amino acids into proteins have advanced significantly over recent years and in this tutorial review we aim to give a general overview of the area. These techniques offer the possibility of modulating the structures and functions of proteins and thus permit the generation of novel designed systems for both biocatalytic and mechanistic studies. Four complementary approaches are discussed in detail along with examples of their application. The advantages and disadvantages of each technique are also discussed. 相似文献
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I. W. Sanderson 《The Journal of the Operational Research Society》1978,29(8):731-739
This paper offers an example of a practical production planning system as used routinely by BP Chemicals Ltd. It is based on the interactive control of a linear programming model embedded in a system for data collection and report production. The model solves a "product mix" type of problem with a multi-criteria objective function. 相似文献
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The particle size distribution of component materials can be important parameter governing the proper function of many industrial products. At present, accurate determination of particle size by currently available methods is difficult for both theoretical and practical reasons. In this paper, some elementary notions regarding particle sizing are reviewed as is the relative performance of commercially available particle sizing instrumentation which could be used for particle size analysis of dry powders. Our results indicate that various particle size instruments yield significantly (even vastly) different particle size distributions for the same material. Without great care on the part of the investigator, the results obtained from any given instrument may not accurately describe the powder in question and thus may cause incorrect technical recommendations. The use of Fraunhofer diffraction instruments on samples containing irregularly shaped small ( < 10 μm) particles of low refractive index requires considerable caution. 相似文献
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S. Roman A.K. Basak J.B.A. England J.M. Nelson N.E. Sanderson F.D. Santos A.M. Eiró 《Nuclear Physics A》1977,289(2):269-274
The tensor analysing power of the 27Al(d, 3He)26Mg reaction has been measured at Ed = 12.4 MeV. The results are reproduced by predictions of the DWBA including D-state components in the 3He wave function. The magnitude of the tensor analysing power provides information on the asymptotic D-state to S-state ratio in the 3He wave function. The value obtained for 3He is in agreement with the corresponding value for 3H. 相似文献