Tunisian traceability system

The concept of metrology first appeared in Tunisia towards 1909. At the end of the 1990s, bodies for evaluating conformity of measurement at different levels have been instituted to meet calibration and testing needs of the national industry. These bodies were divided into three categories: Class A where we find mainly the Central Laboratory for Analysis and Testing LCAE and the National Defence Laboratory DEFNAT; these two laboratories are in charge of the technological upgrading of the other bodies of Class B which, in turn, would transfer their knowledge to the industries, the latter constituting Class C. Nowadays, the accreditation of Tunisian laboratories at the international level by recognized reference foreign bodies and participation in the European proficiency network enabled the national laboratories of Tunisia to establish the degree of equivalence between their measurement results and those of other foreign laboratories.     

A novel carbon/chitosan paste electrode for electrochemical detection of normetanephrine in the urine

Normetanephrine is a marker for pheochromocytoma, a rare catecholamine-secreting and neuroendocrine tumor, that arises from sympathetic and parasympathetic paraganglia. In this work, a novel carbon/chitosan electrode paste was used for sensitive voltammetric determination of normetanephrine and dopamine in the presence of ascorbic acid and uric acid. The modified electrode has shown an increase in the effective area of up to 68%, well-separated oxidation peaks, and an excellent electrocatalytic activity. The electrochemical response characteristics were investigated by cyclic and differential pulse voltammetry. Interestingly, high sensitivity and selectivity in the linear range of normetanephrine, dopamine, ascorbic acid, and uric acid concentrations were observed. The present method was applied in the urine sample and satisfactory results were obtained showing that this electrode is very suitable in pharmaceutical and clinical preparations.     

Evaluation of endothelial cell adhesion onto different protein/gold electrodes by EIS

To study cell attachment to biomaterials, several proteins such as fibronectin, collagen IV, heparin, immunoglobulin G, and albumin have been deposited onto polystyrene adsorbed on a self-assembled monolayer (silane or thiol) on glass or gold, respectively. The different steps of this multilayer assembly have been characterized by electrochemical impedance spectroscopy (EIS). These data are compared to those of adhesion rate, viability percentage, and cytoskeleton labeling for a better understanding of the cell adhesion process to each protein. All the proteins are endothelial cell adhering biomolecules but not with the same features. A linear relationship has been established between adhesion rate and resistance of the endothelial cell/protein interface for all negatively charged proteins.     

Numerical analysis of a linearised fluid-structure interaction problem

Summary. This paper describes the numerical analysis of a time dependent linearised fluid structure interaction problems involving a very viscous fluid and an elastic shell in small displacements. For simplicity, all changes of geometry are neglected. A single variational formulation is proposed for the whole problem and generic discretisation strategies are introduced independently on the fluid and on the structure. More precisely, the space approximation of the fluid problem is realized by standard mixed finite elements, the shell is approximated by DKT finite elements, and time derivatives are approximated either by midpoint rules or by backward difference formula. Using fundamental energy estimates on the continuous problem written in a proper functional space, on its discrete equivalent, and on an associated error evolution equation, we can prove that the proposed variational problem is well posed, and that its approximation in space and time converges with optimal order to the continuous solution. Received May 14, 1999 / Revised version revised October 14, 1999 / Published online July 12, 2000     

Paramagnetic pyrrole-based semiconductor molecular material

The electrochemical oxidation of hexa-N-pyrrolylbenzene in organic media leads, via intramolecular coupling of the pyrrole residues, to the deposition of a molecular semiconductor film on an electrode surface. In situ electron spin resonance–electrochemical experiments reveal that the semiconductor is endowed with both properties of conducting polymers (i.e., reversible oxidation) and polyaromatic molecular materials (i.e., highly paramagnetic). The material, which is easy to process as soft homogeneous thin film, shows a tunable 0 to 1 spin concentration per molecule at room temperature by controlling the electrochemical potential. Contribution to the Fall Meeting of the European Materials Research Society, Symposium D: 9th International Symposium on the Electrochemical–Chemical Reactivity of Metastable Materials, Warsaw, 17th–21st September, 2007. An erratum to this article can be found at     

Polyrotaxanes based on polyethers and β‐cyclodextrin

A polyrotaxane in which β‐cyclodextrins (β‐CDs) are threaded onto a polyether chain was prepared by polycondensation of a β‐CD/bisphenol A (BPA) inclusion complex with aromatic dihalides. Two dihalides, with and without a side chain, were used. This polycondensation results in a polyrotaxane (or pseudopolyrotaxane for polymers without stoppers) with a 1:1 threading ratio when the side chain is present and 2:3 when there is none. The long side chain prevents dethreading of the macrocycles. The best yield and a good threading ratio were obtained when the polycondensation was performed by liquid?solid phase transfer catalysis without solvent (L/S PTC) using 2,5‐bi(iodomethyl)‐4‐methoxy‐(1‐octyloxy)benzene as dihalide. The ¹H NMR and FTIR spectra show that the products consist of β‐CD and polyether. The 2D NOESY NMR spectrum shows that the polyether chains are included in the β‐CD cavity. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 47: 4391–4399, 2009     

Merging Grubbs second-generation catalyst with photocatalysis enables Z-selective metathesis of olefins: scope,limitations, and mechanism

Olefin cross-metathesis is a cornerstone reaction in organic synthesis where stereoselectivity is typically governed by the structure of the catalyst. In this work, we show that merging Grubbs second generation catalyst, a classical E-selective catalyst, with a readily available photocatalyst, enables the exclusive formation of the contra-thermodynamic Z-isomer. The scope and limitations of this unprecedented approach are discussed based on both computational and experimental mechanistic data.

Light is magic! The combination of Grubbs second generation catalyst, a well-known catalyst for E-selective olefin metathesis, with a photosensitizer enables efficient access to the contra-thermodynamic Z-isomers.     

Referential Opacity and Epistemic Logic

Referential opacity is the failure of substitutivity of identity (SI, for short) and in Quine’s view of existential generalization (EG, for short) as well. Quine thinks that its “solution” in epistemic and doxastic contexts, which relies on the notion of exportation, leads to undesirable results. But epistemic logicians such as Jaakko Hintikka and Wolfgang Lenzen provide another solution based on a different diagnosis: opacity is not, as in Quine’s view, due to the absence of reference, it is rather due to the plurality of references; therefore, one must stabilize the reference to restore SI and EG. However, Hintikka’s semantics remains classical in its treatment of existence, which makes EG non-applicable to possible objects, while in Lenzen’s system, EG is applicable by means of a particular quantifier. But this requires adding the predicate of existence to account for real objects. In this paper, I will show the advantages and disadvantages of both solutions and will end by providing an alternative approach to the problem of non-existent objects, which stays into the frame of possible worlds semantics, but introduces some more restrictions, eliminates the problematic predicate of existence, and applies a neutral quantifier to possible non-existent objects.     

Thermal and thermomechanical behavior of Moroccan Boufeggous variety date seeds

Journal of Thermal Analysis and Calorimetry - In this work, the physicochemical and thermomechanical characteristics of date seeds were examined during their pyrolysis under inert atmosphere from...