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The ultraviolet spectra of six alkylchloramines are determined between 220 and 320 nm. The wavelengths of maximum absorption are 244 nm (? = 458 l mol?1 cm?1) for monochloramine, 252 nm (? = 372 l mol?1 cm?1) for methylchloramine, 251 nm (? = 378 l mol?1 cm?1) for ethylchloramine, 250 nm (? = 368 l mol?1 cm?1) for isopropylchloramine, 264 nm (? = 354 l mol?1 cm?1) for dimethylchloramine and 262 nm (? = 315 l mol?1 cm?1) for diethylchloramine. 相似文献
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D. M. J. Smeulders J. P. M. De La Rosette M. E. H. Van Dongen 《Transport in Porous Media》1992,9(1-2):25-37
The propagation of compressional waves in a porous medium is investigated in case the pore liquid contains a small volume fraction of gas. The effect of oscillating gas bubbles is taken into account by introducing a frequency-dependent fluid bulk modulus, which is incorporated in the Biot theory. Using a shock tube technique, new experimental data are obtained for a porous column subjected to a pressure step wave. An oscillatory behaviour is observed, consisting of two distinct frequency bands, which is predicted by the theoretical analysis. 相似文献
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Bosco Peron Leutcha Jean Paul Dzoyem Jean-Bosco Jouda Denis Kehdinga Sema Virginie Flaure Tsague Tankeu Gabin Thierry Mbahbou Bitchagno Billy Toussie Tchegnitegni Flaure Rosette Ehawa Essoung Bruno Ndjakou Lenta Simon Fogue Kouam Florence Delie Alain Meli Lannang Norbert Sewald 《Molecules (Basel, Switzerland)》2022,27(15)
Twenty-two compounds were isolated from the fruit of Albizia lebbeck including one unprecedented, rare amino acid-derived zwitterionic and one new flavone derivative. The isolation was performed on repeated column chromatography over silica gel and their structures were determined by 1D-, 2D-NMR and HR-ESI-MS spectra together with reported data in the literature. The chemophenetic significance is also discussed. Some isolated compounds were reported for the first time to be found in the species. Additionally, compound 2 showed antibacterial activity and compounds 1 and 2 revealed moderate cytotoxic activity against the Raw 264.7 cancer cell line with IC50 values of 37.19 µM and 29.36 µM, respectively. Furthermore, a proposed biosynthetic pathway of compound 1 is described. 相似文献
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Daria Mamaeva Chantal Ripoll Claire Bony Marisa Teigell Florence E Perrin Bernard Rothhut Ivan Bieche Rosette Lidereau Alain Privat Valérie Rigau Hélène Guillon Florence Vachiery-Lahaye Daniele Noel Luc Bauchet Jean-Philippe Hugnot 《BMC neuroscience》2011,12(1):1-12
Background
Evidence suggests that rheumatoid arthritis (RA) may enhance or reduce the progression of Alzheimer's disease (AD). The present study was performed to directly explore the effects of collagen-induced rheumatoid arthritis (CIA) on amyloid plaque formation, microglial activation, and microvascular pathology in the cortex and hippocampus of the double transgenic APP/PS1 mouse model for AD. Wild-type or APP/PS1 mice that received type II collagen (CII) in complete Freund's adjuvant (CFA) at 2 months of age revealed characteristics of RA, such as joint swelling, synovitis, and cartilage and bone degradation 4 months later. Joint pathology was accompanied by sustained induction of IL-1β and TNF-α in plasma over 4 weeks after administration of CII in CFA.Results
CIA reduced levels of soluble and insoluble amyloid beta (Aβ) peptides and amyloid plaque formation in the cortex and hippocampus of APP/PS1 mice, which correlated with increased blood brain barrier disruption, Iba-1-positive microglia, and CD45-positive microglia/macrophages. In contrast, CIA reduced vessel density and length with features of microvascular pathology, including vascular segments, thinner vessels, and atrophic string vessels.Conclusions
The present findings suggest that RA may exert beneficial effects against Aβ burden and harmful effects on microvascular pathology in AD. 相似文献
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