Enlightened sonochemistry

Sonochemistry and photochemistry are initiated by high-energy transient species, which may be prone to mutual interaction. Electronic excitation of solutes by energy transfer from high energy species generated in collapsing bubbles is already supported by experimental evidence. The rates of photochemical reactions can be affected by ultrasound-induced mixing of liquids caused by microstreaming near pulsating cavitation bubbles and shockwaves due to bubble collapse. This may not only improve light absorption but also modify the pathway of reaction by increasing the contact between reagents. Finally, one may speculate about a potentially new chemistry of photoexcited solutes under the extreme conditions inside cavitation microreactors. This work reviews research on the excitation of solutes by sonoluminescence, the combined effects of ultrasound and light on liquid systems and the effect of ultrasound on photocatalytic reactions.     

Matrix extensions and eigenvalue completions, the generic case

In this paper we provide new necessary and sufficient conditions for the so-called eigenvalue completion problem.

     

Symplectic Yang–Mills theory,Ricci tensor,and connections

A Yang–Mills theory in a purely symplectic framework is developed. The corresponding Euler–Lagrange equations are derived and first integrals are given. We relate the results to the work of Bourgeois and Cahen on preferred symplectic connections.     

Targeting cell surface receptors with ligand-conjugated nanocrystals

To explore the potential for use of ligand-conjugated nanocrystals to target cell surface receptors, ion channels, and transporters, we explored the ability of serotonin-labeled CdSe nanocrystals (SNACs) to interact with antidepressant-sensitive, human and Drosophila serotonin transporters (hSERT, dSERT) expressed in HeLa and HEK-293 cells. Unlike unconjugated nanocrystals, SNACs were found to dose-dependently inhibit transport of radiolabeled serotonin by hSERT and dSERT, with an estimated half-maximal activity (EC(50)) of 33 (dSERT) and 99 microM (hSERT). When serotonin was conjugated to the nanocrystal through a linker arm (LSNACs), the EC(50) for hSERT was determined to be 115 microM. Electrophysiology measurements indicated that LSNACs did not elicit currents from the serotonin-3 (5HT(3)) receptor but did produce currents when exposed to the transporter, which are similar to those elicited by antagonists. Moreover, fluorescent LSNACs were found to label SERT-transfected cells but did not label either nontransfected cells or transfected cells coincubated with the high-affinity SERT antagonist paroxetine. These findings support further consideration of ligand-conjugated nanocrystals as versatile probes of membrane proteins in living cells.     

THE SOLUTION PHOTODIMERIZATION OF URIDINE

Abstract— Quenching of the degradative photobleaching of FMN in anaerobic aqueous solution, and of the flavin-sensitized photo-oxidation of EDTA, alcohols, glycols, and glycerol, has been examined using flash techniques. The quenching can be produced by addition of KI, by successive flashes, and by increasing the flavin concentration (self-quenching). It is concluded that the lowest triplet is the photoreactive species in all systems, that the successive flash effect is due to triplet quenching by a reaction product, and that the concentration quenching may be due to either triplet-triplet annihilation or to reaction between a ground-state flavin and a flavin triplet.