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1.
2.
Functional Binding Surface of a β‐Hairpin VEGF Receptor Targeting Peptide Determined by NMR Spectroscopy in Living Cells
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Dr. Donatella Diana Anna Russomanno Dr. Lucia De Rosa Dr. Rossella Di Stasi Dr. Domenica Capasso Dr. Sonia Di Gaetano Dr. Alessandra Romanelli Dr. Luigi Russo Dr. Luca D. D'Andrea Prof. Roberto Fattorusso 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(1):91-95
In this study, the functional interaction of HPLW peptide with VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) was determined by using fast 15N‐edited NMR spectroscopic experiments. To this aim, 15N uniformly labelled HPLW has been added to Porcine Aortic Endothelial Cells. The acquisition of isotope‐edited NMR spectroscopic experiments, including 15N relaxation measurements, allowed a precise characterization of the in‐cell HPLW epitope recognized by VEGFR2. 相似文献
3.
4.
F. S. de Aguiar L. B. Bernardes S. Goulart Rosa Jr. 《Journal of statistical physics》1991,64(3-4):673-682
Metastability in the ferromagneticp-state Potts model defined on the Cayley tree is discussed. It is shown that the sign of the boundary fieldH
s
determines the order of the transition as well as the stability of the low-temperature phase. Lowering the temperature withH
s
>0, a system withp<2 (p>2) will display a second (first)-order transition to a metastable (stable) phase. ForH
s
>0 a second (first)-order transition to a metastable (stable) phase occurs ifp>2 (p<2). In this case the system also has a residual entropy which is negative forp<2. 相似文献
5.
Rosa Erra-Balsells 《Journal of heterocyclic chemistry》1987,24(4):1117-1120
The electron impact mass spectrometric fragmentation pathways for several 2-methyl-, 3-methyl-, 2,3-dimethyl-, 2-aryl- and 3-phenylindole derivatives were investigated. An interesting relationship between the substitution pattern in the framework of the indole derivatives and the fragmentation patterns was observed. 相似文献
6.
7.
A. Di Maio A. Rocco P. Ferraro M. De Rosa P. De Natale S. De Nicola A. Finizio G. Pierattini G. Coppola M. Iodice V. Striano 《Optics and Lasers in Engineering》2007,45(3):385
In view of the growing interest for non-destructive tests of materials, geodynamical monitoring and in general remote sensing, there is a great effort to bring practical optical sensors from research labs to industrial and environmental applications. In this paper, we employ digital holographic technique as an efficient tool for evaluating the strain measurement capability of fiber Bragg gratings (FBG). A cantilever beam has been employed as a test structure under loading test. The strain measurements results obtained by fiber-based sensors have been compared to those obtained by using full-field digital holographic technique and point-wise strain gauge sensors glued on the same cantilever beam. A simple theoretical model is also presented to interpret and compare the experimental results coming from different techniques. 相似文献
8.
Dinesh Topwal U. Manju Sugata Ray S. Raj D. D. Sarma S. R. Krishnakumar M. Bertolo S. La Rosa G. Cautero 《Journal of Chemical Sciences》2006,118(1):87-92
Disordered Sr2FeMoO6 shows a drastic reduction in saturation magnetization compared to highly ordered samples, moreover magnetization as a function
of the temperature for different disordered samples shows qualitatively different behaviours. We investigate the origin of
such diversity by performing spatially resolved photoemission spectroscopy on various disordered samples. Our results establish
that extensive electronic inhomogeneity, arising most probably from an underlying chemical inhomogeneity in disordered samples, is
responsible for the observed magnetic inhomogeneity. It is further pointed out that these inhomogeneities are connected with
composition fluctuations of the type Sr2Fe1+x
Mo1-x
O6 with Fe-rich (x > 0) and Mo-rich (x < 0) regions.
Dedicated to Prof J Gopalakrishnan on his 62nd birthday. 相似文献
9.
A difference between the thermal behaviour of the isotropic and liquid-crystalline state of sonicated DNA in aqueous salt solution containing poly(ethyleneglycol)(PEG) has been demonstrated. On cooling, a different degree of renaturation of thermally denaturated DNA is observed between samples which form the isotropic state and more concentrated samples which on cooling form the cholesteric state. 相似文献
10.
We analyze the critical length for design purposes of six-dimensional spaces invariant under translations and reflections
containing the functions 1, cos t and sin t. These spaces also contain the first degree polynomials as well as trigonometric and/or hyperbolic functions. We identify
the spaces whose critical length for design purposes is greater than 2π and find its maximum 4π. By a change of variables,
two biparametric families of spaces arise. We call shape preservation region to the set of admissible parameters in order
that the space has shape preserving representations for curves. We describe the shape preserving regions for both families.
To our friend Mariano Gasca on occasion of his 60th birthday
Research partially supported by the Spanish Research Grant MTM2006-03388, by Gobierno de Aragón and Fondo Social Europeo. 相似文献