全文获取类型
收费全文 | 362篇 |
免费 | 9篇 |
国内免费 | 1篇 |
专业分类
化学 | 243篇 |
晶体学 | 12篇 |
力学 | 6篇 |
数学 | 11篇 |
物理学 | 100篇 |
出版年
2023年 | 5篇 |
2022年 | 10篇 |
2021年 | 10篇 |
2020年 | 11篇 |
2019年 | 10篇 |
2018年 | 4篇 |
2017年 | 10篇 |
2016年 | 21篇 |
2015年 | 5篇 |
2014年 | 15篇 |
2013年 | 38篇 |
2012年 | 24篇 |
2011年 | 31篇 |
2010年 | 15篇 |
2009年 | 12篇 |
2008年 | 24篇 |
2007年 | 34篇 |
2006年 | 16篇 |
2005年 | 10篇 |
2004年 | 3篇 |
2003年 | 3篇 |
2002年 | 9篇 |
2001年 | 2篇 |
2000年 | 2篇 |
1995年 | 1篇 |
1993年 | 2篇 |
1992年 | 1篇 |
1991年 | 2篇 |
1989年 | 1篇 |
1988年 | 2篇 |
1987年 | 4篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 5篇 |
1981年 | 2篇 |
1979年 | 1篇 |
1978年 | 6篇 |
1977年 | 3篇 |
1976年 | 3篇 |
1975年 | 1篇 |
1974年 | 3篇 |
1971年 | 2篇 |
1970年 | 1篇 |
1938年 | 1篇 |
1926年 | 1篇 |
排序方式: 共有372条查询结果,搜索用时 31 毫秒
1.
2.
The effect of solar features on geospheric conditions leading to geomagnetic storms (GMSs) with planetary index,A
P ≥ 20 and the range of horizontal component of the Earth’s magnetic fieldH such that 250γ <H < 400γ has been investigated using interplanetary magnetic field (IMF), solar wind plasma (SWP) and solar geophysical data
(SGD) during the period 1978–99. Statistically, it is observed that maximum number of GMSs have occurred during the maximum
solar activity years of 21st and 22nd solar cycles. A peculiar result has been observed during the years 1982, 1994 when sunspot
numbers (SSNs) decrease very rapidly while numbers of GMSs increase. No distinct association between yearly occurrence of
disturbed days and SSNs is observed. Maximum number of disturbed days have occurred during spring and rainy seasons showing
a seasonal variation of disturbed days. No significant correlation between magnitude (intensity) of GMSs and importance ofH
α
, X-ray solar flares has been observed. Maximum number of GMSs is associated with solar flares of lower importance, i.e.,
SF during the period 1978-93.H
α
, X-ray solar flares occurred within lower helio-latitudes, i.e., (0–30)°N to (0–30)°S are associated with GMSs. NoH
α
, X-ray solar flares have occurred beyond 40°N or 40°S in association with GMSs. In helio-latitude range (10–40)°N to (10–40)°S,
the 89.5% concentration of active prominences and disappearing filaments (APDFs) are associated with GMSs. Maximum number
of GMSs are associated with solar flares. Coronal mass ejections (CMEs) are related with eruptive prominences, solar flares,
type IV radio burst and they occur at low helio-latitude. It is observed that CMEs related GMS events are not always associated
with high speed solar wind streams (HSSWSs). In many individual events, the travel time between the explosion on the Sun and
maximum activity lies between 58 and 118 h causing GMSs at the Earth. 相似文献
3.
High quality factor of dynamic structures at micro and nano scale is exploited in various applications of micro electro-mechanical
systems (MEMS) and nano electro-mechanical system. The quality factor of such devices can be very high in vacuum. However,
when vacuum is not desirable or not possible, the tiny structures must vibrate in air or some other gas at pressure levels
that may vary from atmospheric to low vacuum. The interaction of the surrounding fluid with the vibrating structure leads
to dissipation, thus bringing down the quality factor. Depending on the ambient fluid pressure or the gap between the vibrating
and the fixed structure, the fluid motion can range from continuum flow to molecular flow giving a wide range of dissipation.
The relevant fluid flow characteristics are determined by the Knudsen number which is the ratio of the mean free path of the
gas molecule to the characteristic flow length of the device. This number is very small for continuum flow and reasonably
big for molecular flow. In this paper, we study the effect of fluid pressure on the quality factor by carrying out experiments
on a MEMS device that consists of a double gimbaled torsional resonator. Such devices are commonly used in optical cross-connects
and switches. We only vary fluid pressure to make the Knudsen number go through the entire range of continuum flow, slip flow,
transition flow, and molecular flow. We experimentally determine the quality factor of the torsional resonator at different
air pressures ranging from 760 Torr to 0.001 Torr. The variation of this pressure over six orders of magnitude ensures required
rarefaction to range over all flow conditions. Finally, we get the variation of quality factor with pressure. The result indicates
that the quality factor, Q, follows a power law, Q ∝P
–r
, with different values of the exponent r in different flow regimes. In the second part of the paper, we propose the use of effective viscosity for considering velocity
slip conditions in solving Navier–Stokes equation numerically. This concept is validated with analytical results for a simple
case and then compared with the experimental results presented in this paper. The study shows that the effective viscosity
concept can be used effectively even for the molecular regime if the air-gap to length ratio is sufficiently small (h
0/L<0.01). As this ratio increases, the range of validity decreases. 相似文献
4.
Ramendra Pratap 《Tetrahedron letters》2007,48(15):2755-2759
A concise synthesis of highly functionalized 5,6-dihydrobenzo[h]quinoline-3-carbonitriles is delineated through base induced ring transformation of 4-sec-amino-2-oxo-5,6-dihydro-2H-benzo[h]chromene-3-carbonitriles with S-methylisothiourea sulfate and 1-carboxamidinepyrazole hydrochloride, separately, in DMF. Under analogous reaction conditions the ring transformation of 4-sec-amino-2-oxo-5,6-dihydro-2H-benzo[h]chromene-3-carbonitriles by formamidine acetate provided 4-sec-amino-benzo[h]quinoline-3-carbonitriles in moderate yields, while with benzamidine hydrochloride, the reaction followed the same mechanism to yield 2-phenyl-4-sec-amino-5,6-dihydrobenzo[h]quinoline-3-carbonitriles. 相似文献
5.
A facile and short synthesis of 2-oxo-4-sec-amino-2,3,5,6-tetrahydrobenzo[f]isoquinoline-1-carbonitriles has been delineated through base catalyzed ring transformation of 5,6-dihydro-2-oxo-4-sec-amino-2H-benzo[h]chromene-3-carbonitrile by cyanoacetamide in excellent yields. 相似文献
6.
A concise, stereodefined synthesis of compactin lactone is described. Samarium(II) iodide mediated intramolecular Reformatsky reaction is the key step in the synthesis. 相似文献
7.
Abstract Aloe vera leaf contains some bioactive compounds that have a strong binding affinity toward estrogen receptor as compared to standard drug tamoxifen. In this study, we have found that the IC50 of Aloe vera leaf extract against breast cancer cell line (MCF-7) is 23?µg/mL which is much lower than the IC50 (332?µg/mL) of Aloe vera leaf extract against non-cancerous cell line (NIH-3T3). We have also calculated the total concentration of phenolic acid (385.662?µg/mL), flavonoids (160.402?µg/mL) and alkaloids (276.754?µg/mL) in Aloe vera leaf extract. The free radical scavenging activity of Aloe vera leaf extract is 67% to 89% (at 50 to 300?µg/ml). Our virtual molecular docking study suggests that bioactive compounds like Aloe-emodin (?8.8?Kcal/mol), 7-hydroxy-2,5 dimethylchromone (?7.5?Kcal/mol), Beta-sitosterol (?7.3?Kcal/mol) etc. have a greater binding affinity toward estrogen alpha receptor as compared to standard drug Tamoxifen (?6.4?Kcal/mol). 相似文献
8.
Ramendra Pratap 《Tetrahedron letters》2005,46(30):5025-5027
The one-pot substituent-directed regioselective synthesis of 1,7-diaryl-2-methyl-4H,5H-pyrano[3,4-c]pyran-4,5-diones 3 as the major and 3,4-diaryl-2-methyl-6-methylsulfanylbenzonitriles 4 as the minor products has been delineated through ring transformation of suitably functionalized 2H-pyran-2-ones 1 with aryl acetones 2. Under similar reaction conditions, 6-aryl-4-sec-amino-2H-pyran-2-ones 5 led, regioselectively, to 3,4-diaryl-2-methyl-6-sec-aminobenzonitriles 6. 相似文献
9.
Ramendra Pratap 《Tetrahedron letters》2007,48(36):6318-6320
An easy and efficient synthesis of phenanthrene derivatives through base catalyzed ring transformation of 4-sec-amino-2-oxo-5,6-dihydro-2H-benzo[h]chromene-3-carbonitriles with acetyltrimethylsilane is described in good yields. The advantage of this reaction is the direct transformation of 2-oxobenzo[h]chromene into phenanthrene via C-C insertion from acetyltrimethylsilane. 相似文献
10.
Sudipta Jena Asit Ray Omprakash Mohanta Prabhat Kumar Das Ambika Sahoo Sanghamitra Nayak Pratap Chandra Panda 《Molecules (Basel, Switzerland)》2022,27(23)
Neocinnamomum caudatum (Lauraceae) plant is used in the traditional system of medicine and is considered a potential source of edible fruits, spices, flavoring agents and biodiesel. The leaves, bark and roots of the species are used by local communities for the treatment of inflammatory responses, such as allergies, sinusitis and urinary tract infections. However, there is no scientific evidence to support the molecular mechanism through which this plant exerts its anti-inflammatory effect. The aim of the current research was to characterize the chemical constituents of bark (NCB) and leaf (NCL) essential oil of N. caudatum and to elucidate its anti-inflammatory action in lipopolysaccharide (LPS)-treated RAW 264.7 cells. Essential oils extracted by hydrodistillation were further subjected to gas chromatography mass spectrometry (GC-MS) analysis. The major constituents in bark essential oil identified as β-pinene (13.11%), α-cadinol (11.18%) and α-pinene (10.99%), whereas leaf essential oil was found to be rich in β-pinene (45.21%), myrcene (9.97%) and α-pinene (9.27%). Treatment with NCB and NCL at a concentration of 25 µg/mL exerted significant anti-inflammatory activity by significantly reducing LPS-triggered nitric oxide (NO) production to 45.86% and 61.64%, respectively, compared to the LPS-treated group. In the LPS-treated group, the production of proinflammatory cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-6 and IL-1β, decreased after treatment with essential oil, alleviating the mRNA levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2. The essential oil also inhibited the production of intracellular ROS and attenuated the depletion of mitochondrial membrane potential in a concentration-dependent manner. Pretreatment with NCB also reduced nuclear factor kappa-B (NF-κB)/p65 translocation and elevated the levels of endogenous antioxidant enzymes in LPS-induced macrophages. The present findings, for the first time, demonstrate the anti-inflammatory potential of both bark and leaf essential oils of N. caudatum. The bark essential oil exhibited a significantly more important anti-inflammatory effect than the leaf essential oil and could be used as a potential therapeutic agent for the treatment of inflammatory diseases. 相似文献