排序方式: 共有12条查询结果,搜索用时 593 毫秒
1.
Background
Growth hormone (GH) plays an incompletely understood role in the development of the central nervous system (CNS). In this study, we use transgenic mice expressing a growth hormone antagonist (GHA) to explore the role of GH in regulating postnatal brain, spinal cord and body growth into adulthood. The GHA transgene encodes a protein that inhibits the binding of GH to its receptor, specifically antagonizing the trophic effects of endogenous GH. 相似文献2.
J. Ph. Poley 《Applied Scientific Research》1955,4(1):173-176
Summary A number of diagrams is presented for deducing the value of the complex dielectric constant in an exact and straightforward
way. 相似文献
3.
A Mukherjee M Dasgupta DJ Hinde CR Morton AC Berriman RD Butt JO Newton H Timmers 《Pramana》2001,57(1):195-198
Fusion cross-sections for the 7Li + 12C reaction have been measured at energies above the Coulomb barrier by the direct detection of evaporation residues. The heavy
evaporation residues with energies below 3 MeV could not be separated out from the α-particles in the spectrum and hence their
contribution was estimated using statistical model calculations. The present work indicates that suppression of fusion cross-sections
due to the breakup of 7Li may not be significant for 7Li + 12C reaction at energies around the barrier. 相似文献
4.
Background
The 5-HT3 receptor is a member of a neurotransmitter-gated ion channel family which includes nicotinic acetylcholine, GABAA, and glycine receptors. While antibodies specific for the 5-HT3A receptor subunit are plentiful, and have revealed a wealth of structural and functional information, few antisera exist for the detection of 5-HT3B receptor subunits. Here we describe the generation and characterisation of a rabbit polyclonal antiserum that specifically recognises 5-HT3B receptor subunits 相似文献5.
The reactivity of the 2,2′-, 2,4′-, 4,4′-dibenzyldiisocyanate (2,2′-, 2,4′-, 4,4′-DBDI) with n-butanol in benzene has been studied. The concentrations of all species were monitored by using high performance liquid chromatography (HPLC). The reactivity of 4,4′-DBDI is similar to that of 4,4′-diphenylmethanediisocyanate (4,4′-MDI). Very strong intramolecular catalytic effects were noticed in the case of 2,2′-DBDI, probably due to the variable molecular geometry. These effects are responsible for the whole reaction pattern. The 2,4′-DBDI NCO ortho and para groups reactivities are different and comparable to that of 2,4-toluylenediisocyanate (2,4-TDI). 相似文献
6.
Boreyko JB Baker CH Poley CR Chen CH 《Langmuir : the ACS journal of surfaces and colloids》2011,27(12):7502-7509
Many natural superhydrophobic structures have hierarchical two-tier roughness which is empirically known to promote robust superhydrophobicity. We report the wetting and dewetting properties of two-tier roughness as a function of the wettability of the working fluid, where the surface tension of water/ethanol drops is tuned by the mixing ratio, and compare the results to one-tier roughness. When the ethanol concentration of deposited drops is gradually increased on one-tier control samples, the impalement of the microtier-only surface occurs at a lower ethanol concentration compared to the nanotier-only surface. The corresponding two-tier surface exhibits a two-stage wetting transition, first for the impalement of the microscale texture and then for the nanoscale one. The impaled drops are subsequently subjected to vibration-induced dewetting. Drops impaling one-tier surfaces could not be dewetted; neither could drops impaling both tiers of the two-tier roughness. However, on the two-tier surface, drops impaling only the microscale roughness exhibited a full dewetting transition upon vibration. Our work suggests that two-tier roughness is essential for preventing catastrophic, irreversible wetting of superhydrophobic surfaces. 相似文献
7.
Summary The results of a series of microwave measurements on C6H5Cl and C6H5Br between −20 and +60°C are recorded. In this region the main dispersion can fairly well be described with a single relaxation
time depending on the temperature. The height of the potential barrier, deduced from this dependence, appears to be of the
same order of magnitude as the total dipoledipole interaction energy. Furthermore the second dispersion is also found to be
strongly temperature-dependent. 相似文献
8.
Lawrence CR Tafoya C William Shuttleworth Yuchio Yanagawa Kunihiko Obata Michael C Wilson 《BMC neuroscience》2008,9(1):105
Background
The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, comprised of SNAP-25, syntaxin 1A, and VAMP-2, has been shown to be responsible for action potential (AP)-dependent, calcium-triggered release of several neurotransmitters. However, this basic fusogenic protein complex may be further specialized to suit the requirements for different neurotransmitter systems, as exemplified by neurons and neuroendocrine cells. In this study, we investigate the effects of SNAP-25 ablation on spontaneous neuronal activity and the expression of functionally distinct isoforms of this t-SNARE in GABAergic and glutamatergic neurons of the adult brain. 相似文献9.
10.