排序方式: 共有44条查询结果,搜索用时 343 毫秒
1.
2.
Russian Journal of Organic Chemistry - The reaction of β-keto esters or acetylacetone with alkyl azides in the system K2CO3/DMSO proved to be a convenient method of synthesis of tri- and... 相似文献
3.
Nazariy T. Pokhodylo Roman D. Savka Olga Ya. Shyyka Mykola D. Obushak 《Journal of heterocyclic chemistry》2020,57(7):2969-2976
The one-pot CuAAC synthesis of (1H-1,2,3-triazol-1-yl)methyl-1,3,4-oxadiazole and (1H-1,2,3-triazol-1-yl)methyl-1,2,4-oxadiazole derivatives via three-component reaction of consequent nucleophilic substitution of chlorine, with azide, and its further “click” reaction, with alkynes, in the presence of CuI was studied. The utility of newly synthesized 2-(azidomethyl)-1,3,4/1,2,4-oxadiazoles and chloromethyl-1,3,4/1,2,4-oxadiazole derivatives was explored, and their limitations were determined. Novel 5-([4-aryl-1H-1,2,3-triazol-1-yl]methyl)-3-(aryl)-1,2,4-oxadiazoles, 2-([4-aryl-1H-1,2,3-triazol-1-yl]methyl)-5-(aryl)-1,3,4-oxadiazoles were obtained in good yields. 相似文献
4.
5.
A new cascade reaction of azides with malononitrile dimer yielding polyfunctional [1,2,3]triazolo[4,5-b]pyridine was found. It was established that during the reaction of aryl azides with malononitrile dimer, under base catalysis, the formed intermediate triazole underwent spontaneous cyclization leading to the pyridine ring annulation. The obtained products have provided a new entry to [1,2,3]triazolo[4,5-b]pyridine. 相似文献
6.
N. T. Pokhodylo V. S. Matiychuk M. D. Obushak 《Chemistry of Heterocyclic Compounds》2010,46(2):140-145
A method was developed for the synthesis of 1-oxo-1H-isothiochromenes from 2-benzofuran-1(3H)-one (phthalide). 3-Bromo-6-chloro-
and 3,6-dibromo-2-benzofuran-1(3H)-ones were prepared by the bromination of 6-chloro- and 6-bromo-2-benzofuran-1(3H)-ones
and were converted by hydrolysis into 5-chloro- or 5-bromo-2-formylbenzoic acids. The condensation of these acids with rhodanine
followed by recyclization gave 7-chloro- and 7-bromo-1-oxo-1H-isothiochromene-3-carboxylic acids. 相似文献
7.
N. T. Pokhodylo V. S. Matiichuk N. D. Obushak 《Russian Journal of Organic Chemistry》2010,46(4):556-560
Diazotization of 1-(aminophenyl)-1H-tetrazoles and subsequent treatment of the diazonium salts with sodium azide gave 1-(azidophenyl)-1H-tetrazoles which were brought into cyclization with ethyl acetoacetate and cyanoacetanilide to obtain 1,2,3-triazole derivatives. Under these conditions, the tetrazole ring may undergo cleavage with formation of cyanamide group. 相似文献
8.
Reaction of 3-aryl-2-bromopropanoic acids esters, products of the Meerwein arylation, with sodium azide afforded alkyl 2-azido-3-arylpropanoates. The latter react with ethyl acetoacetate and phenylacetylene to form 1,2,3-triazole derivatives. A one-pot method for the synthesis of 3-aryl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)-propanoic acid esters via a tricomponent reaction of alkyl 2-bromo-3-arylpropanoates, sodium azide, and phenylacetylene in the presence of CuI was developed. 相似文献
9.
Yu. I. Slyvka N. T. Pokhodylo E. A. Goreshnik M. G. Mys’kiv 《Journal of Structural Chemistry》2014,55(2):368-369
By the AgClO4 interaction with 1-allyl-5-(2-Pyridyl)-1H-tetrazolee (1aPyt) in a methanol solution, an [Ag2(1aPyt)2](ClO4)2 π-complex is obtained, which is studied using single crystal X-ray diffraction. 相似文献
10.