全文获取类型
收费全文 | 128篇 |
免费 | 4篇 |
专业分类
化学 | 32篇 |
力学 | 17篇 |
数学 | 74篇 |
物理学 | 9篇 |
出版年
2022年 | 3篇 |
2021年 | 3篇 |
2020年 | 1篇 |
2019年 | 2篇 |
2018年 | 1篇 |
2017年 | 2篇 |
2016年 | 12篇 |
2015年 | 9篇 |
2014年 | 7篇 |
2013年 | 11篇 |
2012年 | 2篇 |
2011年 | 11篇 |
2010年 | 5篇 |
2009年 | 6篇 |
2008年 | 9篇 |
2007年 | 6篇 |
2006年 | 1篇 |
2005年 | 5篇 |
2004年 | 2篇 |
2003年 | 2篇 |
2002年 | 3篇 |
1998年 | 1篇 |
1997年 | 3篇 |
1996年 | 6篇 |
1994年 | 1篇 |
1992年 | 1篇 |
1991年 | 3篇 |
1989年 | 1篇 |
1987年 | 1篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 2篇 |
1910年 | 1篇 |
排序方式: 共有132条查询结果,搜索用时 281 毫秒
1.
Patrizio Frosini 《Geometriae Dedicata》2004,108(1):105-110
In this paper we prove that for every real-valued Morse function φ on a smooth closed manifold ℳ and every neighborhood U of its critical points a suitable Riemannian metric μ
U
exists such that φ is linear outside
U 相似文献
2.
Maurizio Viale Giovanni Lentini Rosaria Gangemi Patrizio Castagnola Gualtiero Milani Silvia Ravera Nadia Bertola Antonio Carrieri Maria Maddalena Cavalluzzi 《Molecules (Basel, Switzerland)》2022,27(22)
In a previous paper, we demonstrated the synergistic action of the anti-ischemic lubeluzole (Lube S) on the cytotoxic activity of doxorubicin (Dox) and paclitaxel in human ovarian cancer A2780 and lung cancer A549 cells. In the present paper, we extended in vitro the study to the multi-drug-resistant A2780/DX3 cell line to verify the hypothesis that the Dox and Lube S drug association may potentiate the antitumor activity of this anticancer compound also in the context of drug resistance. We also evaluated some possible mechanisms underlying this activity. We analyzed the antiproliferative activity in different cancer cell lines. Furthermore, apoptosis, Dox accumulation, MDR1 downregulation, ROS, and NO production in A2780/DX3 cells were also evaluated. Our results confirm that Lube S improves Dox antiproliferative and apoptotic activities through different mechanisms of action, all of which may contribute to the final antitumor effect. Moderate stereoselectivity was found, with Lube S significantly more effective than its enantiomer (Lube R) and the corresponding racemate (Lube S/R). Docking simulation studies on the ABCB1 Cryo-EM structure supported the hypothesis that Lube S forms a stable MDR1-Dox-Lube S complex, which hampers the protein transmembrane domain flipping and blocks the efflux of Dox from resistant A2780/DX3 cells. In conclusion, our in vitro studies reinforce our previous hypothesis for repositioning the anti-ischemic Lube S as a potentiating agent in anticancer chemotherapy. 相似文献
3.
4.
Patrizio Angelini Fabrizio Frati Michael Kaufmann 《Discrete and Computational Geometry》2011,45(1):88-140
We show that every c-planar clustered graph has a straight-line c-planar drawing in which each cluster is represented by an axis-parallel rectangle, thus solving a problem posed by Eades,
Feng, Lin, and Nagamochi (Algorithmica 44(1):1–32, 2006). 相似文献
5.
The Vapnik–Chervonenkis‐dimension is an index of the capacity of a learning machine. It has been computed in several cases, but always in a Euclidean context. This paper extends the notion to classifiers acting in the more general environment of a manifold. General properties are proved, and some examples of simple classifiers on elementary manifolds are given. A large part of the research is directed toward a still open problem on product manifolds. Copyright © 2007 John Wiley & Sons, Ltd. 相似文献
6.
We investigate a family of isotropic volumetric-isochorically decoupled strain energies based on the Hencky-logarithmic (true, natural) strain tensor log U. The main result of this note is that for n = 2 the considered energies are rank-one convex for suitable values of two material parameters. We also conjecture that there are values of the material parameters such that the corresponding energies are polyconvex. (© 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim) 相似文献
7.
We propose an extension of the cyclic hardening plasticity model formulated by Armstrong and Frederick which includes micropolar effects. Our micropolar extension establishes coercivity of the model which is otherwise not present. We study then existence of solutions to the quasistatic, rate-independent Armstrong–Frederick model with Cosserat effects which is, however, still of non-monotone, non-associated type. In order to do this, we need to relax the pointwise definition of the flow rule into a suitable weak energy-type inequality. It is shown that the limit in the Yosida approximation process satisfies this new solution concept. The limit functions have a better regularity than previously known in the literature, where the original Armstrong–Frederick model has been studied. 相似文献
8.
Patrizio Neff 《Mathematical Methods in the Applied Sciences》2005,28(9):1031-1060
We prove the local existence and uniqueness to a geometrically exact, observer‐invariant membrane‐plate model introduced by the author. The model consists of an elliptic partial differential system of equations describing the equilibrium response of the membrane which is non‐linearly coupled with a viscoelastic evolution equation for exact rotations, taking on the role of an orthonormal triad of directors. This coupling introduces a viscoelastic transverse shear resistance. Refined elliptic regularity results together with a new extended Korn's first inequality for plates and shells allow to proceed by a fixed point argument in appropriately chosen Sobolev‐spaces in order to prove existence and uniqueness. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
9.
Krzysztof Chełmiński Patrizio Neff Sebastian Owczarek 《Journal of Mathematical Analysis and Applications》2015
The purpose of this article is to prove the Hölder continuity up to the boundary of the displacement vector and the microrotation matrix for the quasistatic, rate-independent Armstrong–Frederick cyclic hardening plasticity model with Cosserat effects. This model is of non-monotone and non-associated type. In the case of two space dimensions we use the hole-filling technique of Widman and Morrey's Dirichlet growth theorem. 相似文献
10.
The aims of this note is to present a new model based on a new representation of the curvature energy in the indeterminate couple stress model and to discuss some related choices from the literature. (© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim) 相似文献