Two New Aporphine Alkaloids from Amoora cucullata and their Antibacterial Activity

Chemistry of Natural Compounds - Two new aporphine alkaloids, amocurines D and E (1 and 2), together with five known compounds (3–7), were isolated from the stems of Amoora cucullata. The...     

Potent cytotoxic rocaglamide derivatives from the fruits of Amoora cucullata

Two new rocaglamide derivatives, 1-O-formylrocagloic acid (1) and 3'-hydroxy rocagloic acid (2), together with five known compounds, rocaglaol (3), rocagloic acid (4), 3'-hydroxymethylrocaglate (5), 1-O-formylmethyl rocaglate (6), and methylrocaglate (7), were isolated from the fruits of Amoora cucullata. Their structures were elucidated by spectroscopic methods. Compounds 1-3, 6, and 7 exhibited potent cytotoxicity against KB, BC, and NCI-H187 cell lines, whereas 4 and 5 showed selective cytotoxicity against NCI-H187 cell line.     

A new triterpenoid ester from the fruits of Bruguiera parviflora

A new lupane caffeoyl ester (1), 3-(Z)-caffeoyllupeol, together with five known triterpenoids, lupeol caffeate (2), 3-(Z)-coumaroyllupeol (3), dioslupecin A (4), lupeol (5), and lupenone (6), were isolated from the fruits of Bruguiera parviflora. Their structures were elucidated by spectroscopic methods. Compound 1 exhibited antimalarial activity with an EC50 value of 8.6 microg/ml, but compound 2 was inactive.     

A New Flavone from Oroxylum indicum and its Antibacterial Activity

Chemistry of Natural Compounds - A new flavone, orlumin A (1), together with four known compounds (2–5), was isolated from the fruits of Oroxylum indicum. The structure was elucidated using a...