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Paramaporn Chiewpattanakul Rudy Covis Régis Vanderesse Benjamas Thanomsub Emmanuelle Marie Alain Durand 《Colloid and polymer science》2010,288(9):959-967
Dextran-covered nanoparticles were produced by two different processes: emulsion/solvent evaporation and nanoprecipitation
for the encapsulation of monomyristin. The inner core was formed by poly(lactic acid) or by a hydrophobically modified dextran
(carrying n-decyl chains). According to the core materials and/or to the process, the average size of nanoparticles as well as the extent
of aggregate formation was modulated. It was shown that the presence of monomyristin induced significant modifications on
the characteristics of the resulting suspension (size and aggregate formation). Varying the matrix polymer as well as the
amount of monomyristin in the feed allowed obtaining nanoparticles with convenient size. The use of hydrophobically modified
dextran as the matrix material appeared promising. 相似文献
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